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22 Cards in this Set
- Front
- Back
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malaria
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plasmodium vivax, p.malariae, p.ovale, p.falciparum
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tissue schizonticides
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primaquine:
s/e GIT, anemia (G6PD) doc: radical cure for p.vivax/ovale |
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blood chizonticides
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chloroquine/quinen,mefloquine, pryimethamine
inhibit dihydrofolate reductase DOC: toxoplasmosis given in combo with sulfonamides |
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chloroquine
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-enters and destroys RBC'Smost widely used drug
-mech: inhibits polymerase doc: extra int. amebiasis(liver abscess)/ prophylaxis (p.falciparum) C/I: psoriasis, porphyria |
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quinine
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doc: cerebral malaria, resistant cases
s/e: cinchonism |
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mefloquine
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given to patients resistant to chloroquine
half life:17 days doc: chloroquine resistant cases ci: do not use with quinine and beta blockers |
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amoebiasis
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diloxanide furoate, paramomycin
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systemic amebicides
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emetine, dehydroemetine, chloroquine
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mixed amebicides
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metronidazole
s/e: GIT metallic taste |
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giardiasis
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oral quinacrine; mc in usa
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tape work:
prior laxative admin needed |
prior laxative admin needed
niclosamide trematodes praziquantel |
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nematodes
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mebendazole albendazole
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26 yr old student traveling in india with right upper quadrant discomfort and is diagnosed with amebic liver abscess. the drug of choice is
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metronidazole
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32 year old woman is diagnosed with P.vivax
choloquin not effective because |
the hepatic resivoir of Pvivax is not killed by chlororquine
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nausea cramps, child with giardiasis in day care?
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primaquine- p.vivax
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which of the following drug treatment is recommended for severe multi drug resistance falciparum malaria
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methicillin (multi drug resistance means all the 1st line drug is given and therefore they need to give 2nd line drug)
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32 yr old african america with urge to urinate has burning pain upon urination. urine has ecoli. hx of fatigue, jaundice and was given primaquine at that time- why?
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p.vivax- malaria
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4 year old child who spends 6 days a week in day care has nausea/flatulence, ab cramp and bad smelling stool with giardia lamblia. what is the treatment?
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quinacrine
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chorquine would not be effective in producing radical cure in patient because
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hepatic reservoir of p.vivax is not killed by chloroquine
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clinical use of quinine
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parentral treatment for cerebral malaria, oral treatment for chloroquine resistant falciparum malaria and management with other drugs for acute p.falciparum resistant malarial attacks
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faster drug absorption by
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lung
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most important factor influencing drug absortpion rate following IM injection?
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injection site blood flow
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