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11 Cards in this Set
- Front
- Back
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Rate limiting step of synthesis of acetycholine?
Can be inhibited by? |
Transport of choline into nerve terminal. Inhibited by hemicholinium
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Termination of acetylcholine?
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Metabolism to acetate and choline by enzyme acetylcholinesterase
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Drug used to block release of acetylcholine?
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Botulinum Toxin, which is large and can be used for selective local effects
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Primary transmitter for sympathetic nerves to eccrine sweat glands
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Acetylcholine
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Rate limiting step in synthesis of dopamine and norepinephrine? Can be inhibited by?
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Tyrosine is hydoxylated by tyrosine hydroxylase to DOPA. Inhibited by metyrosine
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Termination of action of dopamine and acetylcholine?
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Diffusion and reuptake, especially by NET and DAT
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Measurement of what helps determine total body production of catecholamines?
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metanephrine, normetanephrine, 3-metoxy-4-hydroxymandelic acid (VMA)
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Norepinephrine and dopamine are metabolized by?
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MAO and COMT
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What type of receptor are muscarinic receptors? Where are they found?
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G protein coupled receptors located on autonomic effector cells
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Reduction in sensitivity of the sensory baroreceptor nerve endings will cause a ______ in sympathetic discharge?
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increase
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What symptom is consistent with diagnosis of botulinum poisoning?
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Cycloplegia
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