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9 Cards in this Set
- Front
- Back
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ranolazine and trimetazidine
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Partial fatty acid oxidation inhibitors (pFOX) shifts energy substrate preference of the heart from fatty acids to glucose
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Ivabradine
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Inhibits SA pacemaker current If
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Abciximab
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Used in unstable angina, is platelet glycoprotein IIb/IIIa inhibitor
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Mechanism of action for nitrates
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Denitration within smooth muscle cells releases NO which causes an increase in cGMP which causes smooth muscle relaxation by dephosphorylation of myosin light chain phosphate
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Nitrates in the treatment of cyanide poisoning
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Nitrates convert ferrous iron to ferric form making methemoglobin. Steps
1.) amyl nitates 2.) IV sodium nitrate 3.) IV sodium thiosulfate Thiocynate is made and excreted |
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Diltiazem and verapamil
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Calcium channel blockers that block conduction in AV node and can be used for AV node arrhythmias
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Diastolic fiber length and diastolic myocardial fiber tension in the heart are reduced by?
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Isosorbide dinitrate
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What causes methemoglobinemia?
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Nitrites
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Ranolazine appears to act through?
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Decreased cardiac force
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