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17 Cards in this Set
- Front
- Back
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This agent has greater affinity for muscarinic receptors and used for postoperative and neurogenic ileus and urinary retention
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Bethanechol
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Only direct acting agent that is very lipid soluble and used in glaucoma
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Pilocarpine
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Indirect-Acting ACh Agonist, alcohol, short DOA and used in diagnosis of myasthenia gravis
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Edrophonium
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Treatment of atropine overdose and glaucoma (because lipid soluable). Enters the CNS rapidly and has a stimulant effect, which may lead to convulsions
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Physostigmine
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Treatment of myasthenia gravis
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Pyridostigmine
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Associated with an increased incidence of cataracts in patients treated for glaucoma
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Long acting cholinesterase inhibitors
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Organophosphate anthelmintic agent with long DOA
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Metrifonate
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The most toxic organophosphate
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Parathion
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Treatment of choice for organophosphate overdose
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Atropine
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This agent regenerates active cholinesterase and is a chemical antagonist used to treat organophosphate exposure
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Pralidoxime
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MOA of Prototypical drug atropine
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Nonselective Muscarinic Antagonists
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Antimuscarinic used to treat manifestations of Parkinson's disease and EPS
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Benztropine, trihexyphenidyl
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Another pneumonic for anticholinergic toxicity
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"dry as a bone, red as a beet, mad as a hatter, hot as a hare, blind as a bat"
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Reversal of blockade by neuromuscular blockers
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Cholinesterase inhibitors
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Only member of depolarizing neuromuscular blocker, causes fasciculation during induction and muscle pain after use; has short duration of action
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Succinylcholine
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Chemical antagonists that bind to the inhibitor of Ach Estrace and displace the enzyme (if aging has not occurred)
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Cholinesterase regenerators, pralidoxime
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Used to treat patients exposed to insecticides such as parathion
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Pralidoxime, atropine
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