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8 Cards in this Set
- Front
- Back
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What is the MOA of cephalosporins?
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1. Inhibits the transpeptidase reaction
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Name two 1st generation cephalosporins and their spectrum?(2)(3)
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1. Cefazolin
2. Cephalexin 1. PEcK 2. Surgical prophylaxis 3. No CNS |
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Name five 2nd generation cepalosporins and their spectrum?
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1. Cefotetam(Disulfuram-like)
2. Cefomendole(disulfuram-like) 3. Loracarbf 4. Cefuroxime 5. Cefomendole (disulfuram) 1. Increased Gram (-) Coverage 2. No CNS, except Cefuroxime 3. HNPEcK |
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Name five 3rd generation cephalosporins? And their spectrum and what they don't work on?
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1. Ceftriaxone(Bile)
2. Cefotaxime 3. Cefdinir 4. Cefixime 5. Cefparazone(Bile) 1. Wide Spectrum 2. All CNS except Cefparazone 3. HN PEcKS 4. Gram (+), (-) cocci and some rods 5. LAME does not work ( Listeria, Atypical, MERSA, Enterococci) |
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What are the 4th generation cephalosporins? Spectrum?
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1. Cefepime
1. Wider spectrum 2. B-lactamase resistant 3. Enters CNS 4. B. LAME |
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What are the five Abx with disulfuram like effects?
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1. Cefoparazone
2. Cefotetan 3. Cefomandole 4. Cetronidazole 5. Chloropropramide |
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What are the side effects of cephalosporins?
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1. Positive Coomb's test
2. Hypoprothrombinemia |
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Name the 2 main causes of meningitis in children? in adults?
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1. Group B strep
2. Strep Agalactiae 1. H. influenza 2. N. meningitidis 3. Strep. pneumonia |
