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37 Cards in this Set
- Front
- Back
the "normal" range
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where 95% of people w/o illnees in question fall
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normal range determined by:
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applying statistical methods to results from a representative sample of the population
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normal range as it relates to drug concentration
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therapeutic range
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normal range AKA
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reference range
reference interval |
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critical value
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lab result that is far outside the normal range, implying morbidity
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factors that affect the normal range (5)
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specimin analyzed
population studied demographics assay used and form of analyte nutritional status |
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assay
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examination and determination as to characteristics; analysis to determine presence or quality of a drug
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analyte
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a substance that is undergoing examination
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quantitative
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results where normal values are reported in ranges
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semi-quantitative
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results reported with varying degrees of positivism
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qualitative
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results with a positive or negative outcome
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what are the 5 rationale for ordering a lab test?
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discover occult disease
confirm suspected diagnosis after signs/symptoms appear determine the stage or activity level of a disease detect recurrence of disease measure the effectiveness of therapy & guide its course |
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discretionary test
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have some reason to do further testing
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screening test
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screen because of a certain age or risk factor (everyone in that category gets the test)
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5 questions to ask yourself when interpreting test results
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does the measured entity exist naturally in the body?
how might the entity get into the tissue or fluid tested? is the entity preferentially stored in any body compartment? does the entity have a normal function in the body? does the entity reflect pathophys in question directly or indirectly? |
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lab errors may be a result of (5)
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improper handling or timing of specimen collection
faulty reagents inaccurate transcription technical performance probs interfering substances |
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lab errors should be suspected when: (4)
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unusual intrapatient trend develops
error's magnitude is great result is not in agreement with a confirmatory test result result is inconsistent with clinical info |
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sensitivity
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deals with the chances that an individual with a particular disease state will have a positive result for the test being measured
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specificity
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deals with the chance that an individual without a particular disease state will have a negative test result from the test being measured
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when to suspect drug-lab test interference (5)
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test results do not correlate with patients s/s
results of diff tests conflict results from same test vary greatly over a short time results from same test change in wrong direction single result is extremely high |
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invasive procedure
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more expensive
more recovery time more difinitive |
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non-invasive procedure
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quick
less expensive less accurate |
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x-rays
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electromag radiation of extremely short wavelengths that is absorbed by denser body parts
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CXR
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x-ray of the chest
most common non-invasive test |
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gastrointestinal study
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invasive
uses radiographic contrast media to visualize the GI |
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IVP
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intravenous pyelogram
invasive kidneys, ureters, bladder radiopaque dye |
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mammography
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non invasive
x-ray of breast used for early detection of breast cancer |
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MRI
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magnetic resonance imaging
based on absorption & transmission of high-frequency ratio waves by water in tissued placed in a strong magnetic field |
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CT
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computerized tomography
non invasive x-ray scans at diff angles provide 3D pic |
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ultrasound
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sonography
non invasive high freq sound waves to determine position or size of soft tissue |
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nuclear medicine studies
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the use of radioactive materials to help diagnose & treat certain diseases
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examples of nuclear medicine studies
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brain scans
bone scans thyroid uptake scan lung & cardiac imaging |
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EKG
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electrocardiography
measurment of the electrical activity in the heart as it pumps blood |
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EEG
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electroencephalography
electical activity of the brain assessment of seizure disorders or states of impared consciousness |
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angiogram
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cardiac catheterization & angiography
invasive tube inserted into blood vessel and passed into heart where constrast medium is released |
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exercise stress test
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non invasive
evaluate clinical & cardiovascular responses to exercise |
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pharmacologic stress test
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invasive
pharmacologic agents produce stress by causing vasodilative response or incr myocardial O2 demand |