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5 Cards in this Set
- Front
- Back
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1. HMG CoA Reductase Inhibitors “Statins”
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a. Block formation of cholesterol in liver (Decrease LDL, Increase HDL)
b. Can be Hepatotoxic – Check Liver enzymes annually c. Can cause Cataracts – annual eye exam recommended d. Interact with CYP450 enzymes – do not take with grapefruit juice e. Take with evening meal or h.s. for best results f. S.e. rabdomylosis ( g. Pregnancy Category X |
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2. Nicotinic Acid
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a. High Dose Vitamin B3
b. S.e. flushing |
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3. Fibrates
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a. Take 30 minutes before meals
b. S.e. gall stones |
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4. Cholesterol Absorption Inhibitors
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a. Inhibit absorption of cholesterol in bile and food
b. Contraindicated in renal dysfunction c. Pregnancy Category X |
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5. Bile Sequestering Drugs
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a. Not absorbed
b. Prevents re-absorption of bile salts from intestine causing liver to manufacture more bile salts from cholesterol c. Decreases absorption of fat soluble vitamins and medications d. S.e. constipation |
