Pharm Cardio

Front 1

Recommended treatment options for stable (nonsustained) ventricular tachycardia?

Back 1

IV Amiodarone or IV Lidocaine

Front 2

1st line agents for treatment of HTN in diabetics

Back 2

ACEis

Front 3

Provide renal protection in diabetics

Back 3

ACEis

Front 4

May increase SCr related to decreases in GFR

Back 4

ACEis

Front 5

Contraindicated in patients with second- degree and third- degree heart block, wide complex ventricular tachycardia.

Back 5

CCB

BB

Front 6

Use with digoxin or phenytoin may lead to bradycardia

Back 6

CCB

Front 7

Vitamin D and Ca compounds decrease effectiveness

Back 7

CCB

Front 8

Antihypertensive effect may be decreased by use of NSAIDs

Back 8

CCB

Front 9

Clinical uses of CCBs

Back 9

HTN
Angina
Arrhythmias (verapamil and diltiazem) --> Convert rhythm, control rate

Esophageal spasm
Vasospastic angina (Prinzmetal’s)

Front 10

Avoid abrupt withdrawal, always taper off, can result in rebound angina and tachycardia.

Back 10

BB

Front 11

Use cautiously when there is renal impairment, history of arrhythmias, pregnancy, lactation, and in geriatric patients.

Back 11

CCB

Front 12

5 therapeutic effects of ACEIs

Back 12

1. Lower BP in HTN

2. Decrease afterload in heart failure

3. Decrease development of overt heart failure

4. Increase patient survival after a myocardial infarction (MI)

5. Decrease diabetic nephropathy progression (captopril only)

Front 13

ACEI Contraindications

Back 13

Renal artery
Acute renal failure
Pregnancy
African Americans with HTN

Front 14

First-line treatment for HTN among diabetics and those with heart failure

Back 14

ACEIs

If cough develops - ARBs

Front 15

Most effective in special populations
> Diabetic nephropathy

> Heart failure: systolic dysfunction

> Cardiac protection after MI or stroke

1st line for HTN in diabetics and/or CHF
CHF

MI

Proteinuria
Diabetic nephropathy

Back 15

ARBs

Front 16

Reduce vasoconstriction which leads to a decrease in afterload and preload

Back 16

ARBs

Front 17

CONTRAINDICATED IN PREGNANCY

Back 17

ACEI

ARB

Front 18

HTN treatment during pregnancy

Back 18

A2-Agonist - Methyldopa

Front 19

Inhibit peripheral vasomotor tone, reducing vasoconstriction and decreasing systemic vascular resistance

First dose effect:

Always give at Night (Orthastatic Hypotension)

Back 19

A1-Receptor Blockers

Front 20

First dose effect seen in what drugs

Back 20

a1-Receptor Blockers

ACEIs

Front 21

Excretion: In feces ( 80%) and urine

Back 21

ARBs

Front 22

Clinical use:

HTN

Benign prostatic hyperplasia (BPH)

Back 22

a1-receptor antagonists

Front 23

Orthostatic Hypotension side effect

Back 23

a1-Receptor Antagonists

Front 24

Direct renin inhibitor, resulting in blockade of the conversion of angiotensinogen to angiotensin 1. Angiotensin I suppresion decreases formation of angiotensin II

Back 24

Aliskiren

Front 25

Effective in reducing proteinuria and BP in diabetic nephropathy pts.

Back 25

Aliskiren (renin inhibitor)

Front 26

ACEI or angiotensin II receptor blockers(ARBs), and a Diuretic used in conjunction, is first line therapy for what?

Back 26

Heart Failure

Front 27

Acute MI first line therapy?

Back 27

BB - Non ISA

ACE/ARB otherwise

Front 28

DONT USE WHAT IN:

COPD
Gout
2nd or 3rd heart block

Pregnancy

Back 28

COPD – Don’t use beta blockers
Gout – Avoid diuretics
2nd or 3rd heart block – Avoid BB and CCB  Pregnancy - Avoid ACEI/ARBs

Front 29

Goals of hypertensive crisis

Back 29

Decrease by 25% within 1 hour

Decrease BP to 160/100 -110 mmHg over next 2-6 hrs

Decrease BP to 130/85 mmHG over next 24-48 hrs

Front 30

Selective Dopamine-1 receptor agonist
> Decreased peripheral vascular
> Increase renal blood, natriuresis, and diuresis

Back 30

Fenoldopam

Front 31

2nd generation DHP CCB
> Coronary and cerebral arterial vasodilation

> Decrease SVR
> No negative inotropic effects

Back 31

Nicardipine

Front 32

3rd generation DHP CCB

> Selective Arteriolar Dilation

> Decrease vascular resistance

> Decrease Afterload
> Increase stroke volume

> Increase cardiac output

> No venous dilation
> No effect on heart rate

Back 32

Clevidipine

Front 33

Which diuretic class is used to clinically treat edema secondary to hyperaldosteronism?

Back 33

Potassium-sparing diuretics

Front 34

Metabolic Acidosis is a side effect reported for which drug class?

Back 34

Potassium-sparing diuretics

Front 35

What is a notable side effect of Triamterene?

Back 35

Blue peepee

Front 36

What is the typical therapy administration of K-sparing diuretics?

Back 36

Adjuct therapy with thiazides and loop diuretics

Front 37

Diuretic classes clinically used to treat Glaucoma?

Back 37

Carbonic Anhydrase Inhibitors - Open-angle Glaucoma (Acetazolamide)

Osmotic Diuretic (Mannitol)

Front 38

Which diuretic is used during acute renal failure?

Back 38

Mannitol

Front 39

Which diuretic can be used in patients with gout, diabetes, and/or low creatinine clearance?

Back 39

Thiazide-like Diuretics

(Clorthalidone/Indapamide/Metolazone)

Front 40

Which diuretic is used as a first line therapy for HTN?

Back 40

Thiazides

Front 41

Management of stable symptomatic heart failure caused by ischemia, HTN, or cardiomyopathy

Back 41

BB

Front 42

Used for prevention of MI and decreased mortality in patient with a recent MI

Back 42

BB

Front 43

Migraine prophylaxis

Back 43

BB