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30 Cards in this Set
- Front
- Back
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Quinidine
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Class 1A antiarrythmic
*M, a-blk |
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Procainamide
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Class 1A antiarrythmic
*M blk, more cardiosuppresant |
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Lidocaine
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Class 1B antiarrythmic
*post-MI, open heart surgery, digitalis toxicity |
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Phenytoin
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Class 1B antiarrythmic
*post-MI, open heart surgery, digitlis toxicity |
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Flecainide
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Class 1C antiarrythmic
*limited use bec inc sudden death in post-MI & VT |
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Encainide
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Class 1C antiarrythmic
*limited use bec inc sudden death in post-MI & VT |
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Propanolol
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Class II Antiarrythmic: b-blkr
*prophylaxis post-MI, SVT |
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Acebutolol
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Class II Antiarrythmic: b-blkr
*prophylaxis post-MI, SVT |
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Esmolol
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Class II Antiarrythmic: b-blkr
*prophylaxis post-MI, SVT |
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Bretylium
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Class III Antiarrythmic: K-blkr
*life-threatening vent arrhythmias |
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Amiodarone
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Class III Antiarrythmic: K-blkr
*life-threatening vent arrhythmias |
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Verapamil
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Class IV Antiarrhythmic: Ca-blkr
*SVT |
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Dilitiazem
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Class IV Antiarrhythmic: Ca-blkr
*SVT |
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Adenosine
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Antiarrhytmic
*PVST, AV nodal arrhythmia |
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Magnesium
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Antiarrhythmic
*Torsades |
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Sotalol
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Antiarrythmic
*2 enantiomers: dec K current, b-blker; for life-threatening ventricular arrhythmias |
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dec Vmax, blk fast Na chan
blk K chan inc APD, ERP |
Class IA antiarrhythmics
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dec Vmac, blk fast Na chan
inc threshold, dec excitability dec APD = inc diast, recovery |
Class IB antiarrhythmics
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lrg dec Vmax
blk fast Na chan, esp purkinje |
Class IC antiarrhythmics
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dec SA, AV nodal activity
dec slope 4 prev b1 activation |
Class II: B-blockers
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inc APD, ERP esp purkinje, vents
dec delayed K rectifier = slows 3 (repol) |
Class III: K chan blockers
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dec SA, AV nodal activity
dec slope 4 |
Class IV: Ca chan blockers
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Na chan opens: depolarization
Phase? |
Phase 0
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Na chan inactivated
Transient K out, Cl in = overshoot Phase? |
Phase 1
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Slow Ca influx
Plateau Phase? |
Phase 2
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Delayed K rectifier
Inactivation of time-dep Ca chan Repolarization Phase? |
Phase 3
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Return to resting membrane potential
Dependent on Na-K ATPase Phase? |
Phase 4
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Inability to respond to stimulus
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Effective Refractory Period (ERP)
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Strong stimulus can elicit response
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Relative Refractory Period (RRP)
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PANS & SANS receptors in the heart
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PANS: M2, slows/dec slope 4
SANS: B1, speeds/inc slope 4 |
