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142 Cards in this Set

  • Front
  • Back
CAP outpatient
p.o. macrolide

(azithromycin or clarithromycin_
CAP outpatient w/ structural lung disease
(COPD< astham, smokers)
p.o. fluoroquinolones

-levofloxacin
-moxiflozacin

-also targets strep. pneumo
Pneumonia (inpatient)

CAP not responding to outpatient Tx. w/ macrolide or CAP admitted directly)
I.v. ceftriaxone or i.v. cefotaxime
+
I.v. azithromycin

OR
moxifloxacin or levofloxacin (i.v.)
inpatient pneumonia w/ PCN allergy
i.v. moxifloxacin or lovefloxacin
HA-pneumonia

VA-pneumonia
i.v. piperacillin- tazobactam

OR
I.v. cefepime

PLUS
i.v. vacnomycin
Step. pneumo
pneumonia
i.v. penicillin G

send home on amoxicillin
Pen G resistant Strep. pneumo
(low level PCN res.)
i.v. cefotaxime

OR

i.v. ceftriaxone
MDR Strep. pneumo
i.v. vancomycin
OR
i.v. moxifloxacin
OR
high dose i.v. levofloxacin
Legionella pneumoniae
i.v. azithromycin
OR
i.v. levofloxacin
OR
i.v. moxifloxacin
PCP pneumonia
trimethoprim-sulfamethoxazole
(larger than normal dose)
aspiration pneumonia
i.v. or p.o clindamycin
outpatient URI w/ PCN allergy
p.o. macrolide
(azithromycin)
B-hemolytic Strep. - inpatient
(pharyngitis, tonsilitis)
i.v. Pen G
B-hemolytic Strep- outpatient
(Pharyngitis, tonilitis)
p.o. amoxicillin
B-hemolytic Strep
PCN allergy
inpatient
(textbooks)
p.o. clindamycin
B-hemolytic Strep
PCN allergy
inpatient
(real world)
p.o. FQ

-levofloxacin

-moxifloxacin
prophylaxis for B-hemolytic Strep.
i.m. procaine pen G

OR

i.m. benzathine
any SSTI caused by a letter strep
inpatient
i.v. pen G
SSTI caused by a letter strep
oupatient
p.o. amoxicillin
infected diabetic foot ulcer
i.v. piperacillin-tazobactam
Primary or Secondary Syphillis
i.m. benzathine penicillin
Neurosyphillis
i.v. Penicillin G
Gonorrhea
i.m. Ceftriaxone
(painful)
CA-meningitis
unknown agent
between 1 mo. and 50years
iv. ceftriaxone OR iv. cefotaxime

PLUS

i.v. vancomycin
CA-meningitis
unknown agent
younger than 1 mo. OR older than 50 yrs.
i.v. ceftriaxone OR i.v. cefotazime

PLUS i.v. vancomycin

PLUS i.v. ampicillin (covers Listeria)
CA-meningitis
bug is H. flu/ Strep .pneumo/ Neisseria
iv. cefotaxime

OR

i.v. ceftriaxone
febrile neutropenia
i.v. peperacillin- tazo

OR
i.v. cefepime

PLUS
i.v. vancomycin
Cellulitis MSSA
Inpatient
i.v. oxacillin or i.v. nafcillin ($$$)

OR

i.v. cefazolin
Cellulitis MSSA
outpatient
p.o. dicloxacillin

OR
p.o. cephalexin

OR
p.o. amoxicillin + clauvanate
Cellulitis MSSA outpatient
PCN allergy
p.o. clindamycin

OR
p.o. doxycycline
Cellulitis MRSA
outpatient
p.o. clindamycin

OR
p.o. trim-sulfa

OR
p.o. doxycycline
MRSA
(hospital)
i.v. vancomycin
MRSA hospital
can't take the vanc.
i.v. daptomycin

OR
i.v./p.o. linesolid

OR
i.v. ceftaroline
MRSA pneumonia
i.v. vancomycin

OR
i.v. linezolid

OR
i.v. ceftaroline
osteomyelitis
(children)
p.o. clindamycin
MRSA osteomyelitis
i.v. vancomycin
Otitis Media
p.o. amoxicillin

OR
p.o. amoxicillin + clauvanate

OR
p.o. cefdinir
Pseudomonas
i.v. piperacillin- tazobactam

OR
i.v. cefepime

OR
i.v. ceftazidime
serious Gram (-) infections
(empiric)
antipseudomonal beta-lactam
(piperacillin OR ticarcillin)

+

aminoglycoside
(STAG-N)
severe Gram (-) infections
pt. PCN allergy
aztreonam
surgical prophylaxix
(non-abdominal)
i.v. cefazolin
gut decontamination
prior to elective GI surgery
p.o. neomycin
(not absorbed from GI)
periop. prophylaxis for GI surgery
i.v. cefoxitin

OR
I.v. cefotetan
penetrating GI trauma
i.v. piperacillin-tazo
lung abscess
i.v. piperacillin-tazo
appendicitis
i.v. piperacillin-tazo
post-op GI surgery
i.v. piperacillin-tazo
inpatient PID
i.v. cefotetan
OR
i.v. cefoxitin

PLUS
i.v. doxycycline
outpatient PID
single i.m. ceftriaxone
+
p.o. metronidazole
+
p.o. doxycycline
Chlamydia
p.o. doxycycline

OR

p.o. macrolide
(azithromycin OR erythromycin OR clarithromycin)
Mycoplasma
p.o. doxycycline

OR

p.o. macrolide
(azithromycin OR erythromycin OR clarithromycin)
Rickettsia
p.o. doxycycline
C. difficile
2 rounds p.o. metronidazole

THEN

p.o. vancomycin

THEN

P.O. FIDIXIMYCIN
VRE
i.v. OR p.o. linezolid

OR

i.v. daptomycin
Gram (+) bacteremia
i.v. vancomycin
enterococcus
i.v. ampicillin

if res. = i.v. vancomycin

if vanc. res. = i.v. or p.o. linezolid OR daptomycin
MDR (vanc res.) enterococcus
i.v. or p.o. linezolid

OR

i.v. daptomycin
anaerobic infections w/ PCN allergy
i.v. metronidazole
Borrelia burgdoferi
p.o. doxycycline
uncomplicated UTI
(OP)
trim-sulfa
complicated UTI
(OP)
p.o. cipro

OR

p.o. levofloxacin
UTI pregnant female
p.o. nitrofurantoin
Nocardia
trim-sulfa
Nocardia (sulfonamida allergy)
minocycline OR doxycycline

OR
ceftriaxone

OR imipenem
diarrhea
-Salmonella
-Shigella
-E. coli
-Campylobacter
p.o. ciprofloxacin
pyelonephritis
i.v. ceftriaxone

OR

I.v. cefoxatime

send home on
p.o. cefpodoxime
Complicated UTI inpatient
(nursing home)
i.v. ceftriaxone
OR
i.v. cefoxatime

send home on
p.o. cefpodoxime
Protease Inhibitors
Ritonavir + Lopinavir

Atazanavir
Atazanavir
Protease Inhibitor
Ritonavir
Protease Inhibitor
Integrase inhibitor
Raltegravir
NNRTI
Nevirapine

Efavirenz
Efavirenz
NNRTI
NRTI
Lopinavir
Abacavir
Tenofovir
Emtrictabine
Zidovidine
Efavirnez v. Emrticatabine
Efavirnez = NNRTI

Emtricatabine= NRTI
Fusion Inhibitors
Maravioc

Enfuvirtide
Enfuvirtide
Fusion inhibitor

gp41

last resort
Red Man Syndrome
vancomycin

give diphenhydramine
Seizurecillin
imipenem
turns everything orange
rifampin
Pyrodoxone res. peripheral neuropathy
Isoniazid
teeth problems
tetracyclines

doxycycline
minocycline
DOC herpes keratitis
trifluridine
DOC CMV retinitis
Gancyclovir retinal implants
dont take with milk or cations
tetracyclines
Cipro S/E
tendon rupture

Q-T prolongation (slow K+ current)

phototoxicity
slows K+ current
cipro

Q-T prolongation
DOC Giardia
***Metranidazole***

Nitazoxanide
DOC Entomoeba
***Metranidazole***

follow-up= paromycin
Chloroquine
p.o. once a week

all sensitive strains, NOT hypnozoites
Primaquine
only drug to kill hypnozoites

hemolytic anemia in G-6-P
methemhemoglobinemia
not for G-6-P malaria patients
Primaquine
Methemhemoglobinemia in G-6-P
Primaquine
Mefloquine
only drug to kill MDR P. falciparum

makes you crazy

prophylaxis?
anti-malaria
crazies
Mefloquine
DOC P. ovale
cholropquine + primaquine
DOC P. vivax
chloroquin + primaquine
effective against MDR malaaris
Mefloquine- rarely used

DOC
doxycycline + clindamycin
for severe P. falciparum when NPO
Quinidine

(cardiac toxicity)
Quinidine
for severe P. falciparum when NPO

cardiac toxicity
DOC chloroquine resistant malaria
atovaquone- proguanil
DOC toxo- immunocompetant
pyrimethamine- sulfazidine
DOC Toxo- AIDS
trimethoprom- sulfa
DOC Threadworrm
Ivermectin
DOC Pinworms
Albendazole (mixed infections)

Mebendazole (+round/ tapeworms)

Pyrantel pamoate
DOC mixed worm infections
albendazole
DOC Schistomes
Praziquantel
DOC Cestodes
albendazole
DOC Trematodes
(Schistomes/ Flukes)

Praziquantel
anti-helmetic

reversible alopecia
Albendazole
DOC Scabies
5% permethrin
DOC Lice
1% Permethrin
Ivermectin
P.o. scabies

Threadworm
p.o. scabies
Ivermectin
DOC HIV Cryptococcus
amphoteracin B
Amphoteracin B
S/E
-nephrotoxic

-shake and bake (fever + chills)

-hypochromic anemia
shake and bake syndrome
Amphroteracin B
Amphoteracin B after Azoles
NO!

azoles remove acting site of AmphoB
DOC Asperilligus
***Voriconazole***

Amphoteracin B

Posaconazole

(not fluconazole)
Asperilligus and Fluconazole
NOPE
Posaconazole
-all fungi covered

-must have fat in GI (poor F)

-only p.o.
DOC Asperilligus or Candida not responding to Tx
Caspofungin

"salvage therapy"

$$$
DOC Cryptococcal meningitis
Amphoteracin B

Flucytosine (for CNS)

Fluconazole (for life)
Amphoteracin B
Administration
i.v. or topical
Flucytosine
Administration
p.o.
MET (tines)
tolnaftate (topical)

giseofulvin (p.o.)
Oral candida
nystatin (oral suspension)

clotrimazole (oral troches)
DOC Ringworm
Griseofulvin (topical)

also:
Ketonazole
Terbinafine
fluconazole
Athletes foot
topical TERBINAFINE
Onchomycosis
topical TERBINAFINE
salvage antifungal
Capsofuscine (i.v)

Aspirgillus
Candida
PCP
DOC Aspirgillus
Voriconazole

(AmphoB will also work)
Where griseofulvin builds up where
keratin cells
AmphoB
S/e
-shake and bake

-renal toxic

-hypochromatic anemia
DOC ringtowm
griseofulvin
DOC Cryptococcus
flucytosine (5-FT)

+

amphoteracin
linezolid
S/E
Serotonin syndrome

optic neuropathy (blindness)

bone marrow suppression
photosensitive
doxycycline

(tetracycline)
renal or ototoxicity
vancomycin
azithromycine
S/E
n/v

painful iv

use topically for acne
M. avium DOC
Ethambutol

Macrolide
(azithromycin)
Pinworms
Albendazole

Pyrantel-panzoate