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142 Cards in this Set
- Front
- Back
CAP outpatient
|
p.o. macrolide
(azithromycin or clarithromycin_ |
|
CAP outpatient w/ structural lung disease
(COPD< astham, smokers) |
p.o. fluoroquinolones
-levofloxacin -moxiflozacin -also targets strep. pneumo |
|
Pneumonia (inpatient)
CAP not responding to outpatient Tx. w/ macrolide or CAP admitted directly) |
I.v. ceftriaxone or i.v. cefotaxime
+ I.v. azithromycin OR moxifloxacin or levofloxacin (i.v.) |
|
inpatient pneumonia w/ PCN allergy
|
i.v. moxifloxacin or lovefloxacin
|
|
HA-pneumonia
VA-pneumonia |
i.v. piperacillin- tazobactam
OR I.v. cefepime PLUS i.v. vacnomycin |
|
Step. pneumo
pneumonia |
i.v. penicillin G
send home on amoxicillin |
|
Pen G resistant Strep. pneumo
(low level PCN res.) |
i.v. cefotaxime
OR i.v. ceftriaxone |
|
MDR Strep. pneumo
|
i.v. vancomycin
OR i.v. moxifloxacin OR high dose i.v. levofloxacin |
|
Legionella pneumoniae
|
i.v. azithromycin
OR i.v. levofloxacin OR i.v. moxifloxacin |
|
PCP pneumonia
|
trimethoprim-sulfamethoxazole
(larger than normal dose) |
|
aspiration pneumonia
|
i.v. or p.o clindamycin
|
|
outpatient URI w/ PCN allergy
|
p.o. macrolide
(azithromycin) |
|
B-hemolytic Strep. - inpatient
(pharyngitis, tonsilitis) |
i.v. Pen G
|
|
B-hemolytic Strep- outpatient
(Pharyngitis, tonilitis) |
p.o. amoxicillin
|
|
B-hemolytic Strep
PCN allergy inpatient (textbooks) |
p.o. clindamycin
|
|
B-hemolytic Strep
PCN allergy inpatient (real world) |
p.o. FQ
-levofloxacin -moxifloxacin |
|
prophylaxis for B-hemolytic Strep.
|
i.m. procaine pen G
OR i.m. benzathine |
|
any SSTI caused by a letter strep
inpatient |
i.v. pen G
|
|
SSTI caused by a letter strep
oupatient |
p.o. amoxicillin
|
|
infected diabetic foot ulcer
|
i.v. piperacillin-tazobactam
|
|
Primary or Secondary Syphillis
|
i.m. benzathine penicillin
|
|
Neurosyphillis
|
i.v. Penicillin G
|
|
Gonorrhea
|
i.m. Ceftriaxone
(painful) |
|
CA-meningitis
unknown agent between 1 mo. and 50years |
iv. ceftriaxone OR iv. cefotaxime
PLUS i.v. vancomycin |
|
CA-meningitis
unknown agent younger than 1 mo. OR older than 50 yrs. |
i.v. ceftriaxone OR i.v. cefotazime
PLUS i.v. vancomycin PLUS i.v. ampicillin (covers Listeria) |
|
CA-meningitis
bug is H. flu/ Strep .pneumo/ Neisseria |
iv. cefotaxime
OR i.v. ceftriaxone |
|
febrile neutropenia
|
i.v. peperacillin- tazo
OR i.v. cefepime PLUS i.v. vancomycin |
|
Cellulitis MSSA
Inpatient |
i.v. oxacillin or i.v. nafcillin ($$$)
OR i.v. cefazolin |
|
Cellulitis MSSA
outpatient |
p.o. dicloxacillin
OR p.o. cephalexin OR p.o. amoxicillin + clauvanate |
|
Cellulitis MSSA outpatient
PCN allergy |
p.o. clindamycin
OR p.o. doxycycline |
|
Cellulitis MRSA
outpatient |
p.o. clindamycin
OR p.o. trim-sulfa OR p.o. doxycycline |
|
MRSA
(hospital) |
i.v. vancomycin
|
|
MRSA hospital
can't take the vanc. |
i.v. daptomycin
OR i.v./p.o. linesolid OR i.v. ceftaroline |
|
MRSA pneumonia
|
i.v. vancomycin
OR i.v. linezolid OR i.v. ceftaroline |
|
osteomyelitis
(children) |
p.o. clindamycin
|
|
MRSA osteomyelitis
|
i.v. vancomycin
|
|
Otitis Media
|
p.o. amoxicillin
OR p.o. amoxicillin + clauvanate OR p.o. cefdinir |
|
Pseudomonas
|
i.v. piperacillin- tazobactam
OR i.v. cefepime OR i.v. ceftazidime |
|
serious Gram (-) infections
(empiric) |
antipseudomonal beta-lactam
(piperacillin OR ticarcillin) + aminoglycoside (STAG-N) |
|
severe Gram (-) infections
pt. PCN allergy |
aztreonam
|
|
surgical prophylaxix
(non-abdominal) |
i.v. cefazolin
|
|
gut decontamination
prior to elective GI surgery |
p.o. neomycin
(not absorbed from GI) |
|
periop. prophylaxis for GI surgery
|
i.v. cefoxitin
OR I.v. cefotetan |
|
penetrating GI trauma
|
i.v. piperacillin-tazo
|
|
lung abscess
|
i.v. piperacillin-tazo
|
|
appendicitis
|
i.v. piperacillin-tazo
|
|
post-op GI surgery
|
i.v. piperacillin-tazo
|
|
inpatient PID
|
i.v. cefotetan
OR i.v. cefoxitin PLUS i.v. doxycycline |
|
outpatient PID
|
single i.m. ceftriaxone
+ p.o. metronidazole + p.o. doxycycline |
|
Chlamydia
|
p.o. doxycycline
OR p.o. macrolide (azithromycin OR erythromycin OR clarithromycin) |
|
Mycoplasma
|
p.o. doxycycline
OR p.o. macrolide (azithromycin OR erythromycin OR clarithromycin) |
|
Rickettsia
|
p.o. doxycycline
|
|
C. difficile
|
2 rounds p.o. metronidazole
THEN p.o. vancomycin THEN P.O. FIDIXIMYCIN |
|
VRE
|
i.v. OR p.o. linezolid
OR i.v. daptomycin |
|
Gram (+) bacteremia
|
i.v. vancomycin
|
|
enterococcus
|
i.v. ampicillin
if res. = i.v. vancomycin if vanc. res. = i.v. or p.o. linezolid OR daptomycin |
|
MDR (vanc res.) enterococcus
|
i.v. or p.o. linezolid
OR i.v. daptomycin |
|
anaerobic infections w/ PCN allergy
|
i.v. metronidazole
|
|
Borrelia burgdoferi
|
p.o. doxycycline
|
|
uncomplicated UTI
(OP) |
trim-sulfa
|
|
complicated UTI
(OP) |
p.o. cipro
OR p.o. levofloxacin |
|
UTI pregnant female
|
p.o. nitrofurantoin
|
|
Nocardia
|
trim-sulfa
|
|
Nocardia (sulfonamida allergy)
|
minocycline OR doxycycline
OR ceftriaxone OR imipenem |
|
diarrhea
-Salmonella -Shigella -E. coli -Campylobacter |
p.o. ciprofloxacin
|
|
pyelonephritis
|
i.v. ceftriaxone
OR I.v. cefoxatime send home on p.o. cefpodoxime |
|
Complicated UTI inpatient
(nursing home) |
i.v. ceftriaxone
OR i.v. cefoxatime send home on p.o. cefpodoxime |
|
Protease Inhibitors
|
Ritonavir + Lopinavir
Atazanavir |
|
Atazanavir
|
Protease Inhibitor
|
|
Ritonavir
|
Protease Inhibitor
|
|
Integrase inhibitor
|
Raltegravir
|
|
NNRTI
|
Nevirapine
Efavirenz |
|
Efavirenz
|
NNRTI
|
|
NRTI
|
Lopinavir
Abacavir Tenofovir Emtrictabine Zidovidine |
|
Efavirnez v. Emrticatabine
|
Efavirnez = NNRTI
Emtricatabine= NRTI |
|
Fusion Inhibitors
|
Maravioc
Enfuvirtide |
|
Enfuvirtide
|
Fusion inhibitor
gp41 last resort |
|
Red Man Syndrome
|
vancomycin
give diphenhydramine |
|
Seizurecillin
|
imipenem
|
|
turns everything orange
|
rifampin
|
|
Pyrodoxone res. peripheral neuropathy
|
Isoniazid
|
|
teeth problems
|
tetracyclines
doxycycline minocycline |
|
DOC herpes keratitis
|
trifluridine
|
|
DOC CMV retinitis
|
Gancyclovir retinal implants
|
|
dont take with milk or cations
|
tetracyclines
|
|
Cipro S/E
|
tendon rupture
Q-T prolongation (slow K+ current) phototoxicity |
|
slows K+ current
|
cipro
Q-T prolongation |
|
DOC Giardia
|
***Metranidazole***
Nitazoxanide |
|
DOC Entomoeba
|
***Metranidazole***
follow-up= paromycin |
|
Chloroquine
|
p.o. once a week
all sensitive strains, NOT hypnozoites |
|
Primaquine
|
only drug to kill hypnozoites
hemolytic anemia in G-6-P methemhemoglobinemia |
|
not for G-6-P malaria patients
|
Primaquine
|
|
Methemhemoglobinemia in G-6-P
|
Primaquine
|
|
Mefloquine
|
only drug to kill MDR P. falciparum
makes you crazy prophylaxis? |
|
anti-malaria
crazies |
Mefloquine
|
|
DOC P. ovale
|
cholropquine + primaquine
|
|
DOC P. vivax
|
chloroquin + primaquine
|
|
effective against MDR malaaris
|
Mefloquine- rarely used
DOC doxycycline + clindamycin |
|
for severe P. falciparum when NPO
|
Quinidine
(cardiac toxicity) |
|
Quinidine
|
for severe P. falciparum when NPO
cardiac toxicity |
|
DOC chloroquine resistant malaria
|
atovaquone- proguanil
|
|
DOC toxo- immunocompetant
|
pyrimethamine- sulfazidine
|
|
DOC Toxo- AIDS
|
trimethoprom- sulfa
|
|
DOC Threadworrm
|
Ivermectin
|
|
DOC Pinworms
|
Albendazole (mixed infections)
Mebendazole (+round/ tapeworms) Pyrantel pamoate |
|
DOC mixed worm infections
|
albendazole
|
|
DOC Schistomes
|
Praziquantel
|
|
DOC Cestodes
|
albendazole
|
|
DOC Trematodes
|
(Schistomes/ Flukes)
Praziquantel |
|
anti-helmetic
reversible alopecia |
Albendazole
|
|
DOC Scabies
|
5% permethrin
|
|
DOC Lice
|
1% Permethrin
|
|
Ivermectin
|
P.o. scabies
Threadworm |
|
p.o. scabies
|
Ivermectin
|
|
DOC HIV Cryptococcus
|
amphoteracin B
|
|
Amphoteracin B
S/E |
-nephrotoxic
-shake and bake (fever + chills) -hypochromic anemia |
|
shake and bake syndrome
|
Amphroteracin B
|
|
Amphoteracin B after Azoles
|
NO!
azoles remove acting site of AmphoB |
|
DOC Asperilligus
|
***Voriconazole***
Amphoteracin B Posaconazole (not fluconazole) |
|
Asperilligus and Fluconazole
|
NOPE
|
|
Posaconazole
|
-all fungi covered
-must have fat in GI (poor F) -only p.o. |
|
DOC Asperilligus or Candida not responding to Tx
|
Caspofungin
"salvage therapy" $$$ |
|
DOC Cryptococcal meningitis
|
Amphoteracin B
Flucytosine (for CNS) Fluconazole (for life) |
|
Amphoteracin B
Administration |
i.v. or topical
|
|
Flucytosine
Administration |
p.o.
|
|
MET (tines)
|
tolnaftate (topical)
giseofulvin (p.o.) |
|
Oral candida
|
nystatin (oral suspension)
clotrimazole (oral troches) |
|
DOC Ringworm
|
Griseofulvin (topical)
also: Ketonazole Terbinafine fluconazole |
|
Athletes foot
|
topical TERBINAFINE
|
|
Onchomycosis
|
topical TERBINAFINE
|
|
salvage antifungal
|
Capsofuscine (i.v)
Aspirgillus Candida PCP |
|
DOC Aspirgillus
|
Voriconazole
(AmphoB will also work) |
|
Where griseofulvin builds up where
|
keratin cells
|
|
AmphoB
S/e |
-shake and bake
-renal toxic -hypochromatic anemia |
|
DOC ringtowm
|
griseofulvin
|
|
DOC Cryptococcus
|
flucytosine (5-FT)
+ amphoteracin |
|
linezolid
S/E |
Serotonin syndrome
optic neuropathy (blindness) bone marrow suppression |
|
photosensitive
|
doxycycline
(tetracycline) |
|
renal or ototoxicity
|
vancomycin
|
|
azithromycine
S/E |
n/v
painful iv use topically for acne |
|
M. avium DOC
|
Ethambutol
Macrolide (azithromycin) |
|
Pinworms
|
Albendazole
Pyrantel-panzoate |