Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
197 Cards in this Set
- Front
- Back
|
H1 Antagonist (1st generation)
|
Side Effects: sedation (permeable to BBB - hits H4-R); orthostatic hypotension (adrenergic block); dry mouth, impaired vision & accommodation; antiparkinsonism (cholinergic block); serotonin block; Uses: motion sickness/Meniere's disease (cholinergic block); local anesthesia (voltage gated Na channel block at high doses; alternative if lidocaine allergy); allergies (urticaria, rhinitis); cough suppression; somnifacients; ineffective for asthma
|
|
|
H1 Antagonist (2nd generation)
|
Side Effects: no sedation (non-permeable to BBB); orthostatic hypotension (adrenergic block); dry mouth, impaired vision & accommodation; antiparkinsonism (cholinergic block); serotonin block; Uses: less effective for motion sickness (cholingeric block); local anesthesia (voltage gated Na channel block at high doses; alternative if lidocaine allergy); allergies (urticaria, rhinitis); cough suppression; somnifacients; ineffective for asthma
|
|
|
Chlorpheniramine
|
"H1 Antagonist (1st generation)
|
|
|
Diphenhydramine
|
H1 Antagonist (1st generation)
|
|
|
Pyrilamine
|
H1 Antagonist (1st generation)
|
|
|
Cyclizine
|
H1 Antagonist (1st generation)
|
|
|
Promethazine
|
H1 Antagonist (1st generation); orthostatic hypotension
|
|
|
Cyproheptadine
|
H1 Antagonist (1st generation); 5HT Antagonist - use for postgastrectomy dump syndrome (prevent diarrhea)
|
|
|
Fexofenadine
|
H1 Antagonist (2nd generation)
|
|
|
Loratadine
|
H1 Antagonist (2nd generation)
|
|
|
Cetirizine
|
H1 Antagonist (2nd generation)
|
|
|
Acrivastine
|
H1 Antagonist (2nd generation)
|
|
|
Buspirone
|
5HT Agonist; anxiolytic
|
|
|
Sumatriptan (triptans)
|
5HT Agonist; 5HT1d/1b agonists; treat migraines (vasoconstriction and reduce blood flow in brain) - repeat use not as effective
|
|
|
Odansetron
|
5HT Antagonist; 5HT3 block - treat acute chemotherapy induced nausea and vomiting; not good for motion sickness; efficacy enhanced with dexamethasone/NK1 antagonist; headaches, dizziness, constipation
|
|
|
Ritaserine
|
5HT Antagonist; 5HT2 block - reduce thromboxane formation, alter bleeding time
|
|
|
Ketanserin
|
5HT Antagonist; 5HT1c, 5HT2 block - treat hypertension (receptors in bood vessels)
|
|
|
Dinoprostone (Prostin E2, Prepidil, Cervidil)
|
PGE2 Analog; labor facilitation (local administration, oxytocic use); 2nd trimester abortion; prevention of NSAID induced peptic ulcer
|
|
|
Misoprostol
|
PGE1 Analog; used in combination with RU-486 & an antiprogestin (mifepristone) - day after pill for early abortion; prevention of NSAID induced peptic ulcer; orally active; cytoprotective (gastric) - increase bicarbonate & mucus secretion, decrease HCl secretion (at high concentrations); uterine cramps, menstrual disorders, GI
|
|
|
Alprostadil
|
PGE1 Analog; PGI2 Analog; maintains patency of ductus arteriosus; treat erectile dysfunction (2nd line); prevention of NSAID induced peptic ulcer
|
|
|
Carboprost tromethamine
|
PGF2a Analog; 2nd trimester abortion; controls unresponsive postpartum hemorrhage
|
|
|
Latanoprost
|
PGF2a Analog; treat glaucoma; topically active
|
|
|
Bimatoprost
|
PGF2a Analog; treat glaucoma
|
|
|
Travoprost
|
PGF2a Analog; treat glaucoma
|
|
|
Epoprostenol (Flolan)
|
PGI2 Analog; treat primary pulmonary hypertension
|
|
|
Iloprost
|
PGI2 Analog; treat primary pulmonary hypertension
|
|
|
Trepostinil
|
PGI2 Analog; treat primary pulmonary hypertension
|
|
|
Indomethacin
|
NSAID-COX1
|
|
|
Sulindac
|
NSAID-COX1
|
|
|
Ibuprofen
|
NSAID-COX1/2
|
|
|
Nabumetone
|
NSAID-COX2
|
|
|
Aspirin
|
NSAID-COX (irreversible)
|
|
|
Celecoxib (Celebrex)
|
NSAID-COX2; less potent than Refecoxib (Vioxx); treat arthitis
|
|
|
Rofecoxib (Vioxx)
|
NSAID-COX2; increased incidence MI-withdrawn from market
|
|
|
Naproxen
|
NSAID-COX1/2; treat arthritis
|
|
|
Dexamethasone
|
Glucocorticoid-PLA2 inhibition; antiemetic (mechanism unknown)
|
|
|
Monteleukast (Singulair)
|
LTD4 Antagonist; treat asthma, bronchoconstriction
|
|
|
Zafirleukast (Accolate)
|
LTD4 Antagonist; treat asthma, bronchoconstriction
|
|
|
Zileuton (Zyflo)
|
5-Lipoxygenase Inhibitor; prevention of exercise induced asthma (fast acting)
|
|
|
Dazoxiben
|
TXA2 Synthase Inhibitor; treat acute and chronic coronary artery disease
|
|
|
Hydrazaline
|
Renal Vasodilation
|
|
|
Minoxidil
|
Renal Vasodilation
|
|
|
ACE Inhibitor
|
Side Effects: dry cough (linked to elevation of bradykinin/substance P which are broken down by ACE); angioedema; fetus toxicity in pregnant women (renal development) Uses: Antioxidant function, reduce aldosterone secretion, block angiotensin I->angiotensin II; minimize vascular disease in diabetics
|
|
|
Captopril
|
ACE Inhibitor
|
|
|
Enalapril
|
ACE Inhibitor
|
|
|
Ramipril
|
ACE Inhibitor
|
|
|
Losartan
|
AT1 Blocker
|
|
|
Aliskiren
|
Renin Inhibitor; treat hypertension, CHF
|
|
|
Calcium Channel Blocker
|
Mechanism: blocks L-Type Ca channel; decrease SA node rate, increase AV node refractory period; dilate arterioles; Side Effects: no orthostatic hypotension; dizziness; headaches; peripheral edema (ankle); bradycardia (verapamil, diltiazem); mild diuretic effect; Contraindications: beta blockers (especially with verapamil and diltiazem); Uses: supraventricular arrhythmia; Raynaud's; prevent premature labor; epilepsy (cerebral vasodilation); esophageal motor disorders
|
|
|
Verapamil
|
Calcium Channel Blocker - Phenylalkylamine (more selective for cardiac than vascular tissue); treat atrial arrhythmias, vascular headache prophylaxis, blocks p170 glycoprotein; extension metabolism in liver (low bioavailability if hepatic insufficiency)
|
|
|
Nifedipine
|
Calcium Channel Blocker-Dihydropyridine; oral and sublingual; causes rapid fall in blood pressure
|
|
|
Nicardipine
|
Calcium Channel Blocker-Dihydropyridine; treat subarachnoid hemorrhage (if blood pressure elevated)
|
|
|
Amlodipine (Norvasc)
|
Calcium Channel Blocker-Dihydropyridine ("kinder and gentler")
|
|
|
Felodipine
|
Calcium Channel Blocker-Dihydropyridine
|
|
|
Isradipine
|
Calcium Channel Blocker-Dihydropyridine
|
|
|
Nimodipine
|
Calcium Channel Blocker-Dihydropyridine; treat subarachnoid hemorrhage (if blood pressure not elevated)
|
|
|
Diltiazem
|
Calcium Channel Blocker-Benzothiazipine
|
|
|
Bepridil
|
Calcium Channel Blocker (last resort); sodium channel blocking activity; pro-lithium activity
|
|
|
Nitrates
|
Side Effects: orthostatic hypotension, tachycardia, headache, tolerance
|
|
|
Amyl Nitrite
|
Nitrates; inhalational; no longer used; "poppers"
|
|
|
Nitroglycerin
|
Nitrates
|
|
|
Glygeryl Trinitrate
|
Nitrates
|
|
|
Isosorbide Dinitrate
|
Nitrates
|
|
|
Isosorbide Mononitrate
|
Nitrates; active metabolite of Isosorbide Dinitrate; 100% bioavailability
|
|
|
Erythrityl Tetranitrate
|
Nitrates
|
|
|
Methylxanthines
|
Mechanism: adenosine antagonism; inhibition phosphodiesterases; histone deacetylation
|
|
|
Theophylline
|
Methylxanthine; poor solubility; complex with ethylenediamine to form aminophylline; treat COPD, asthma; low therapeutic index-must be able to measure plasma levels; rapid oral absorption; elimination by liver metabolism (cimetidine inhibits CYP450 and can increase theophylline levels)
|
|
|
Caffeine
|
Methylxanthine
|
|
|
Theobromine
|
Methylxanthine
|
|
|
Ergot Alkaloids
|
Mechanism: agonism, partial agonism, and antagonism at serotinergic, adrenergic, and dopaminergic receptors; amides more active at serotonin receptors, amino acids have alpha-adrenergic and dopaminergic actions; Side Effects: overdose-gangrene and vasospasm not reversible by alpha or serotonin antagonists; GI; hallucinations (LSD); intense vasoconstriction; Uses: migraine; post-partum uterine bleeding (increase in frequency and contractile force of uterine smooth muscle at low doses; prolonged contraction at high doses); Contraindications: hypertension, vascular disease, pregnancy
|
|
|
Ergonovine (ergometrine)
|
Ergot Alkaloids-Amine; treat post-partum uterine bleeding (greatest selectivity for uterine smooth muscle; oxytocin 1st line)
|
|
|
Methyl ergonovine
|
Ergot Alkaloids-Amine
|
|
|
Methysergide
|
Ergot Alkaloids-Amine
|
|
|
Ergotamine
|
Ergot Alkaloids-Amino Acid; diagnostic test for migraine
|
|
|
Dihydroergotamine
|
Ergot Alkaloids-Amino Acid
|
|
|
Bromocriptine
|
Ergot Alkaloids-Amino Acid; inhibits prolactin release (dopamine agonist); treat pituitary tumor
|
|
|
Cabergoline
|
Ergot Alkaloids; dopamine agonist
|
|
|
Pergolide
|
Ergot Alkaloids; dopamine agonist
|
|
|
Sildenafil (Viagra)
|
PDE Inhibitor
|
|
|
Tadalafil (Cialis)
|
PDE Inhibitor
|
|
|
Vardenafil (Levitra)
|
PDE Inhibitor
|
|
|
Beta Blocker
|
Contraindications: Prinzmetal angina; asthma; COPD; Raynaud's; peripheral artery disease; sinus bradycardia; AV block; diabetes
|
|
|
Acebutolol
|
Beta Blocker; B1; partial agonist
|
|
|
Atenolol (Tenormin)
|
Beta Blocker; B1; nightmares
|
|
|
Betaxolol
|
Beta Blocker; B1
|
|
|
Bisoprolol
|
Beta Blocker; B1
|
|
|
Esmolol (Reviblock)
|
Beta Blocker; B1; rapidly metabolized (found in crash carts)
|
|
|
Propanolol
|
Beta Blocker; anesthetic action; nightmares
|
|
|
Diuretic - Carbonic Anhydrase Inhibitor
|
Uses: Glaucoma (open angle); altitude sickness prophylaxis; short term diuretic; catamenial epilepsy; correct metabolic alkalosis; alkalinize urine - increase solubility of uric acid and cysteine, increase aspirin excretion, increase phosphate excretion; Side Effects: hypercloremic metabolic acidosis; renal stone formation; renal potassium wasting; hepatic encephalopathy; Contraindications: potassium depletion; hepatic encephalopathy
|
|
|
Acetazolamide (Diamox)
|
Diuretic - Carbonic Anhydrase Inhibitor
|
|
|
Dichlorphenamide
|
Diuretic - Carbonic Anhydrase Inhibitor
|
|
|
Methazolamide
|
Diuretic - Carbonic Anhydrase Inhibitor
|
|
|
Glycerin
|
Diuretic - Osmotic; oral
|
|
|
Isosorbide
|
Diuretic - Osmotic; oral
|
|
|
Mannitol
|
Diuretic - Osmotic; IV
|
|
|
Urea
|
Diuretic - Osmotic; IV
|
|
|
Diuretic - Loop (High Ceiling)
|
Sulfonamides except for ethacrynic acid; secretion inhibited by NSAID, probenecide; decreases both concentrating and diluting ability of kidney; Mechanism: blocks Na+/K+/2Cl- (greater Cl- than Na+ loss); Uses: acute hyperglycemia, hyperkalemia, acute renal failure, anion overdose, hypertension, CHF, cirrhosis of liver, nephritic syndrome, chronic heart failure, acute renal failure; Side Effects: Ca, Mg loss; venodilation; decreased pulmonary wedge pressure; isosthenuria; increased prostaglandin & renin release; blockade tubuloglomerular feedback; hypokalemic metabolic alkalosis; hyperuricemia; interstitial nephritis (if sensitive to sulfonamides); hyperglycemia
|
|
|
Furosemide (Lasix)
|
Diuretic - Loop (High Ceiling); ototoxicity
|
|
|
Ethacrynic Acid (Edecrin)
|
Diuretic - Loop (High Ceiling); prodrug; give if sulfa allergy
|
|
|
Bumetanide (Bumex)
|
Diuretic - Loop (High Ceiling); less dependent on tubular organic acid secretion (more lipophilic); more potent than furosemide
|
|
|
Torsemide (Demadex)
|
Diuretic - Loop (High Ceiling)
|
|
|
Azosemide
|
Diuretic - Loop (High Ceiling)
|
|
|
Muzolimine
|
Diuretic - Loop (High Ceiling)
|
|
|
Piretanide
|
Diuretic - Loop (High Ceiling)
|
|
|
Tripamide
|
Diuretic - Loop (High Ceiling)
|
|
|
Brain Natriuretic Peptide
|
produced in ventricular myocytes; marker for CHF; inhibits renin release; fosters loss of salt and water
|
|
|
Diuretic - Thiazide
|
Mechanism: block Na+/Cl- symporter in distal convoluted tubule; Uses: edema in heart, liver and renal disease; decrease blood pressure, potentiates antihypertensive drugs; calcium nephrolithiasis and osteoporosis (increases Ca2+ reabsorption, causes hypocalciuria); nephrogenic diabetes insipidus; Side Effects: reduce GFR; hypokalemia, hypochloremia, dilutional hyponatremia, decreased glucose tolerance (diabetogenic effect with higher doses), hyperuricemia, hypercalcemia, hypokalemia (digitalis toxicity, quinidine induced torsades de pointes); Contraindications: CHF (decreased GFR)
|
|
|
Bendroflumethiazide
|
Diuretic - Thiazide
|
|
|
Chlorothiazide
|
Diuretic - Thiazide; low potency
|
|
|
Hydrochlorothiazide
|
Diuretic - Thiazide; prolonged duration of action; side effects above 25mg
|
|
|
Hydroflumethiazide
|
Diuretic - Thiazide
|
|
|
Methyclothiazide
|
Diuretic - Thiazide
|
|
|
Polythiazide
|
Diuretic - Thiazide
|
|
|
Trichlormethiazide
|
Diuretic - Thiazide
|
|
|
Indapamide (Lozol)
|
Diuretic - Thiazide-like
|
|
|
Chlorthalidone (Hygroton)
|
Diuretic - Thiazide-like
|
|
|
Metolazone
|
Diuretic - Thiazide-like
|
|
|
Quinethazone
|
Diuretic - Thiazide-like
|
|
|
Diuretic - Potassium Sparing
|
Mechanism: block ENaC in collecting tubule (bind alpha subunit); Side Effects: hyperkalemia, acidosis
|
|
|
Amiloride
|
Diuretic - Potassium Sparing; treat edema & hypertension together with thiazides; treat Liddle's syndrome; treat lithium induced nephrogenic diabetes insipidus; Gitelman's syndrome
|
|
|
Triamterine
|
Diuretic - Potassium Sparing; interaction with NSAIDS
|
|
|
Mineralocorticoid Receptor Antagonist
|
Uses: edema and hypertension with thiazides, primary aldosteronism, secondary aldosteronism, diuretic of choice for edema in hepatic cirrhosis, reduce morbidity and mortality in class II and class IV heart failure
|
|
|
Eplerenone
|
Mineralocorticoid Receptor Antagonist; weaker but more selective (no androgen antagonist activity)
|
|
|
Spironolactone
|
Mineralocorticoid Receptor Antagonist; androgen antagonist activity; hyperkalemia; gynecomastia (anti-androgenic effects); gastritis; peptic ulcer disease; drowsiness; lethargy
|
|
|
Conivaptan
|
Vasopressin receptor antagonist
|
|
|
NaHCO3
|
Antacid - systemic, irreversible; alkalosis
|
|
|
CaCO3
|
Antacid - nonsystemic, reversible
|
|
|
Mg(OH)2
|
Antacid - nonsystemic, reversible; renal insufficiency and diarrhea
|
|
|
Al(OH)3
|
Antacid - nonsystemic, reversible; constipation
|
|
|
Pirenzepine
|
M1 Antagonist
|
|
|
Telenzepine
|
M1 Antagonist
|
|
|
Pipenzolate
|
Muscarinic Antagonist
|
|
|
Propantheline
|
Muscarinic Antagonist
|
|
|
Antihistamine - H2 Antagonist
|
Uses: reduce acid secretion; Side Effects: GI (diarrhea, constipation); headache; breast enlargement; confusion in elderly patients; fatigue; muscle pain; inhibits P450 (mostly Cimetidine)
|
|
|
Cimetidine
|
Antihistamine - H2 Antagonist; least potent
|
|
|
Ranitidine
|
Antihistamine - H2 Antagonist; inhibits P450 less potently than Cimetidine (more potent than Cimetidine so no significant interactions with P450)
|
|
|
Famotidine
|
Antihistamine - H2 Antagonist; most potent
|
|
|
Nizatidine
|
Antihistamine - H2 Antagonist; highest bioavailability (90%)
|
|
|
H+/K+ ATPase Inhibitor - substituted benzimidazoles
|
Uses: antimicrobial activity (H. pylori); Side Effects: GI; increase gastrin secretion; increased susceptibility to infections; modified absorption of drugs
|
|
|
Omeprazole
|
H+/K+ ATPase Inhibitor - substituted benzimidazoles
|
|
|
Lansoprezole
|
H+/K+ ATPase Inhibitor - substituted benzimidazoles
|
|
|
Sucralfate
|
Gastric Protective Agent; indigestion, constipation
|
|
|
Bismuth
|
Gastric Protective Agent; antimicrobial activity; antidiarrheal
|
|
|
Metoclopramide
|
Dopamine Antagonist; Cholinomimetic properties - use to increase gastric emptying in reflux esophagitis and emergency surgery; 5HT4 agonist; 5HT3 antagonist; treat nausea and vomiting due to chemotherapy
|
|
|
Castor Oil
|
Laxative - Stimulant; increases cAMP; effect in small intestine
|
|
|
Diphenylmethane
|
Laxative - Stimulant; effect in large intestine
|
|
|
Bisacodyl
|
Laxative - Stimulant; effect in colon
|
|
|
Phenolphthalein
|
Laxative - Stimulant
|
|
|
Anthraquinones (senna, cascara, aloes)
|
Laxative - Stimulant; effect in colon; stimulates enteric nerves in increase motility
|
|
|
Sulfate and phosphate salts of Mg, Na, K
|
Laxative - Osmotic; Contraindication - Mg salts in renal insufficiency; dilute solutions more rapid onset
|
|
|
Psyllium
|
Laxative - Bulk ; treat IBS-C
|
|
|
Bran
|
Laxative - Bulk
|
|
|
Cellulose
|
Laxative - Bulk
|
|
|
Glycerin
|
Laxative - Lubricant
|
|
|
Mineral Oil
|
Laxative - Lubricant
|
|
|
Dioctyl sodium sulfosuccinate (Docusate)
|
Laxative - Surface acting
|
|
|
Lactulose
|
Laxative; reduce blood ammonia in chronic portal hypertension and hepatic encephalopathy
|
|
|
Polyethylene glycol
|
Laxative
|
|
|
Diphenoxylate
|
Opioid - Meperidine analogue; combined with atropine to prevent abuse (Lomotil); antidiarrheal; habit forming; adverse effects with barbiturates, alcohol, MAO-I
|
|
|
Loperamide (Imodium)
|
Opioid - Piperidine analogue; doesn't cross BBB (less abuse, interactions with barbiturates, alcohol); treat IBS-D
|
|
|
Kaolin
|
Antidiarrheal; often used with opiates
|
|
|
Ursodiol
|
Bile Acid; treat cholesterol gallstones
|
|
|
Lubiprostone
|
PGE Analog; activates type 2 Cl- channel (ClC-2); treat IBS-C
|
|
|
Dicyclomine
|
Muscarinic Antagonist; antispasmodic; treat IBS-D
|
|
|
Hyoscyamine
|
Muscarinic Antagonist; antispasmodic; treat IBS-D
|
|
|
Alosetran
|
5HT Antagonist; 5-HT3; treat IBS-D; decreases pain, bloating, nausea; causes severe constipation, ischemic colitis
|
|
|
Tegaserod
|
5HT Agonist; 5-HT4; treat IBS-C; cardiovascular complications-withdrawn
|
|
|
5-ASA
|
5-ASA formulation; topical effects; bound to sulfasalazine to prevent absorption in small intestine; cleaved in terminal ileum; Side Effects:nausea, GI, headaches, arthralgias, myalgias, bone marrow suppression, allergy to sulfasalazine
|
|
|
Pentasa
|
5-ASA formulation; time release in small intestine
|
|
|
Asacol
|
5-ASA formulation; pH sensitive release (pH 7) in distal ileum, colon
|
|
|
Lialda
|
5-ASA formulation; pH sensitive release in colon
|
|
|
Methylprednisone
|
Glucocorticoid; antiemetic (mechanism unknown)
|
|
|
Budesonide
|
Glucocorticoid; prednisone analog
|
|
|
Azathioprine
|
achieve and maintain remission in inflammatory bowel disease; better bioavailability; liver toxicity, bone marrow suppression; reduce dose if on allopurinol (which interferes with metabolism)
|
|
|
6-mercaptopurine
|
achieve and maintain remission in inflammatory bowel disease; liver toxicity, bone marrow suppression; reduce dose if on allopurinol (which interferes with metabolism)
|
|
|
Methotrexate
|
Antimetabolite; inhibits dihydrofolate reductase; prevents synthesis of purines and thymidine; oral, intramuscular, subcutaneous; treat inflammatory bowel disease (not antiproliferative at these doses; interfere with IL-1); bone marrow suppression, megaloblastic anemia, alopecia; folate supplementation to decrease side effects
|
|
|
TNF-a Antibody
|
Uses: inflammatory bowel disease (1/3 lose efficacy) Side Effects: infections, serum sickness type illness, liver failure, demyelinating disorders, CHF
|
|
|
Infliximab
|
TNF-a Antibody; IV
|
|
|
Adalimumab
|
TNF-a Antibody; subq injection
|
|
|
Certolizumab
|
TNF-a Antibody; subq injection
|
|
|
Natalizumab
|
Anti-Integrin Antibody; alpha 4 subunit of integrin; treat intractable Crohn's disease; Contraindications: other immunosuppressive therapies
|
|
|
Aprepitant
|
Neurokinin Antagonist; treat nausea/vomiting with chemotherapy
|
|
|
Droperidol
|
Dopamine Antagonist - D2 block; treat nausea/vomiting
|
|
|
Meclozine
|
H1 Antagonist; lacks drowsiness; treat nausea/vomiting
|
|
|
Nabilone
|
Cannabinoid; treat nausea/vomiting after chemotherapy
|
|
|
Dronabinol
|
Cannabinoid; treat nausea/vomiting after chemotherapy
|
|
|
Guanadrel
|
Peripheral Inhibitor
|
|
|
Guanethidine
|
Peripheral Inhibitor
|
|
|
Reserpine
|
Peripheral Inhibitor
|
|
|
Clonidine
|
Central Alpha-2 Agonist
|
|
|
Guanabenz
|
Central Alpha-2 Agonist
|
|
|
Guanfacine
|
Central Alpha-2 Agonist
|
|
|
Methyldopa
|
Central Alpha-2 Agonist; treat preeclampsia; no orthostatic hypotension
|
|
|
Doxazosin
|
Alpha-1 Blocker
|
|
|
Prazosin
|
Alpha-1 Blocker; decreases PVR; minimal tachycardia (baroreceptor reflex); orthostatic hypotension, sexual dysfunction; use with B-blockeres in pheochromocytoma
|
|
|
Terazosin
|
Alpha-1 Blocker
|
|
|
Sodium Nitroprusside
|
treat acute hypertensive emergencies
|
