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4 Cards in this Set
- Front
- Back
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Beta-lactamase inhibitor
-drugs |
-clavulanic acid
-sulbactam -tazobactam |
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Beta-lactamase inhibitor
-mechanism of action |
-little antimicrobial activity of their own
-bind with chromosomally mediated penicillinases and plasmid mediated penicillinases |
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Clavulonic acid
-spectrum |
-extended amoxicillin spectrum
-resembles second generation cephalosporins -improved activity against Enterobacteriaceae, Staph., anaerobics |
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Clavulonic acid/Amoxicillin
-adverse effects |
-GI upset
-hepatic lipidosis in cats due to inappetance (stop administering in cats when no longer eating) -don't use in non-ruminant herbivores |
