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5 Cards in this Set
- Front
- Back
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antitubercular agents
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Isoniazid, Rifampin, Ethambutol, Pyrazinamide, Streptomycin
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Isoniazid
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antitubercular - hepatotoxicity (greater with age), fast-acetylators require daily dosing, peripheral neuritis, INH reaction with pyridoxin (depletes it) leads to mental disturbances
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Rifampin
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induces hepatic drug metabolism (dose adjust after 7-10 days), stains fluids red
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Ethambutol
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optic neuritis, hyperuricemia (gout)
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Pyrazinamide
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hepatotoxicity (2-3% serious), hyperuricemia (gout)
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