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10 Cards in this Set
- Front
- Back
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lovastatin
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statin - HMG-CoA reductase inhibiton
familial combined hyperlipoprotienemia, familial hypercholesterolemia, familial ligand-defective apoB -GI effects -myopathy -liver dysfunction -rhabdomyolysis |
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simvastatin
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statin - HMG-CoA reductase inhibition
familial combined hyperlipoproteinemia, familial hypercholesterolemia, familial ligand-defective apoB -GI effects -myopathy -liver dysfunction -rhabdomyolysis |
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pravastatin
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statin - HMG-CoA reductase inhibiton
familial combined hyperlipoproteinemia, familial hypercholesterolemia, familial ligand-defective apoB -GI effects -myopathy -liver dysfunction -rhabdomyolysis |
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atorvastatin
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statin - HMG-CoA reductase inhibition
familial combined hyperlipoproteinemia, familial hypercholesterolemia, familial ligand-defective apoB -GI effects -myopathy -liver dysfunction -rhabdomyolysis |
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cholestyramine
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resin - bind bile acids
familial hypercholesterolemia -GI effects -constipation -decreased drug and fat soluble vitamin absorptions |
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colestipol
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resin - bind bile acids
familial hypercholesterolemia -GI effects -constipation -decreased drug and fat soluble vitamin absorptions |
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niacin (nicotinic acid or vitamin B3)
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inhibit VLDL synthesis and secretion by liver
all hypercholesterol and triglyceridemias -cutaneous flush -GI effects -hepatotoxicity -hyperglycimia -hyperuricemia |
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gemfibrozil
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fibrate - activation of PPAR receptor
primary chylomicronemia, familial hypertriglyceridemia, familial combined hyperlipoproteinemia, familial dysbetalipoproteinemia -GI effects, rash |
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fenofibrate
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fibrate - activation of PPAR receptor
primary chylomicronemia, familial hypertriglyceridemia, familial combined hyperlipoproteinemia, familal dysbetalipoproteinemia -GI effects -rash |
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ezetimibe
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inhibit absorption of dietary cholesterol
familal combined hyperlipoproteinemia, familal hypercholesterolemia, familial ligand-defective apoB -well tolerated as monotherapy, can be combined with statin |
