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69 Cards in this Set
- Front
- Back
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Antidote/treatment for Toxic dose of Acetaminophen:
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N-acetylcysteine
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Antidote/treatment for Toxic dose of Salicylates:
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Alkalinize urine
Dialysis |
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Antidote/treatment for Toxic dose of Anticholinesterases (Organophosphates):
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-Atropine
-Pralidoxime |
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Antidote for Antimuscarinic, Anticholinergic overdose:
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Physostigmine salicylate
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Antidote for B-blocker toxicity:
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Glucagon
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5 steps in treating DIGITALIS toxicity:
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1. Stop dig
2. Lidocaine 3. Anti-dig Fab fragments 4. Mg2+ 5. Normalize K+ SLAMN |
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Antidote for Iron toxicity:
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Deferoxamine
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4 Antidotes for Lead toxicity:
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Calcium-EDTA
Dimercaprol Succimer Penicillamine |
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2 Antidotes for Arsenic, Mercury or Gold poisoning:
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Dimercaprol
Succimer |
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Antidote for Copper, Arsenic, or Gold poisoning:
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Penicillamine
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3 Antidotes for Cyanide poisoning:
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-Nitrites
-Hydroxocobalamin -Thiosulfate |
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Antidote for Methemoglobin toxicity:
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Methylene blue
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Antidote for Carbon monoxide toxicity:
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-100% O2
-Hyperbaric O2 |
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Antidote for Methanol or Ethylene glycol (antifreeze) toxicity:
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-Fomepizole
-Ethanol -Dialysis |
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Antidote for Opioid overdose:
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Naloxone or Naltrexone
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Antidote for Benzodiazepine overdose:
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Flumazenil
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Antidote for TCA overdose:
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Sodium Bicarb NaHCO3
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Antidote for Heparin overdose:
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Protamine sulfate
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Antidote for Warfarin overdose:
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Vitamin K
FFP |
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Antidote for tPA/Streptokinase overdose:
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Aminocaproic acid
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Where is there high risk for lead poisoning?
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Houses with chipped paint
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7 Signs/Symptoms of Lead poisoning:
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-Lead Lines on gingivae/bones
-Encephalopathy -RBC Basophilic stippling -Anemia - sideroblastic -Abdominal Colic -Drops - wrist/foot |
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What is the 1st line treatment for lead poisoning?
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Dimercaprol and Ca-EDTA
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What is the treatment for KIDS with lead poisoning?
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Succimer - it sucks to be a kid who eats lead
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What enzyme metabolizes Ethylene glycol, Methanol, AND Ethanol?
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Alcohol dehydrogenase
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What is the metabolite of Ethylene glycol and what are 2 results of its overproduction?
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Oxalic acid
-Acidosis -Nephrotoxicity |
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What is the metabolite of Methanol and what are 2 results of its overproduction?
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Formaldehyde/Formic Acid
-SEVERE Acidosis -Retinal damage |
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hat is the metabolite of Ethanol and what are 4 results of its overproduction?
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Acetaldehyde
-Nausea/vomiting -Headache -Hypotension |
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What normally helps to reduce the toxicity due to Acetaldehyde?
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Aldehyde dehydrogenase normally converts Acetaldehyde to Acetic acid
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What drug inhibits Aldehyde dehydrogenase?
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Disulfiram
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Atropine-like CV side effects
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Tricyclics TCAs
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Cardiac toxicity (2)
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-Doxorubicin (Adriamycin)
-Daunorubicin |
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Coronary vasospasm
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Cocaine
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Cutaneous flushing (4)
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CAN VANCO? yes...
CCB's Adenosine Niacin Vancomycin |
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Torsades des pointes (3)
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Class III - Sotalol/Amiodarone
Class IA - Quinidine Cisapride |
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Agranulocytosis - 3
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Clozapine
Carbamazepine Colchicine |
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Aplastic anemia - 3
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NSAIDs
Benzene Chloramphenicol |
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Gray baby syndrome
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Chloramphenicol
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Hemolysis in G6PD deficient people - 6
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-Sulfonamides (SMX)
-Isoniazid INH -Nitrofurantoin -Primaquine -Ibuprofen -Aspirin |
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Thrombotic complications
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OCPS - estrogen/progesterone
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Cough
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ACE inhibitors - but not ARBs like losartan
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Pulmonary fibrosis - 3
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Bleomycin
Amiodarone Busulfan |
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Acute Cholestatic Hepatitis
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Macrolides
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Focal to Massive Hepatic necrosis - 4
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HAVA
Halothane Acetaminophen Valproic acid Amanita phalloides |
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Hepatitis
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INH (isoniazid)
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Pseudomembranous colitis
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Clindamycin
Ampicillin |
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Adrenocortical insufficiency
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Glucocorticoid removal (HPA suppression - adrenal atrophy)
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Gynecomastia acronym
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Some drugs create awesome knockers
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Gynecomastia
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-Spironolactone
-Digitalis -Cimetidine -Alcohol (chronic use) -Ketoconazole |
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Hot flashes
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Tamoxifen
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Gingival hyperplasia
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Phenytoin
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Osteoporosis - 2
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Corticosteroids
Heparin |
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Photosensitivity
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SAT for a photo
-Sulfonamides -Amiodarone -Tetracycline |
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SLE-like syndrome
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Not HIPP to have lupus
-Hydralazine -INH -Procainamide -Phenytoin |
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Tendonitis, Tendon rupture, Cartilage damage in kids:
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Fluoroquinolones - Ciproflox
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Fanconi's syndrome (renal)
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Expired tetracycline
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Interstitial nephritis
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Methicillin
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Hemorrhagic cystitis - 2
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Cyclophosphamide
Ifosfamide |
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Cinchonism
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Quinidine/Quinine
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Diabetes insipidus - 2
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Lithium
Demeclocycline |
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Seizures - 3
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Buproprion
Imipenem/Cilastatin |
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Tardive dyskinesia
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Antipsychotics
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Disulfiram-like Reaction - 4
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Metronidazole
Some Cephalosporins Procarbazine Sulfonylureas |
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Nephrotoxicity AND Neurotoxicity
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Polymyxins
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Nephrotoxicity AND Ototoxicity 3
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Aminoglycosides
Loop diuretics Cisplatin |
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Acronym for P450 INDUCERS
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Queen Barb takes Phenphen and Refuses Grease-Saturated Carbs
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What are the P450 inducers?
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Quinidine
Barbiturates Phenytoin Rifampin Griseofulvin St. John's wort Carbamazepine |
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Acronym for the P450 INHIBITORS:
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Inhibitors Stop Cyber Kids from Eating Grapefruit
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What are the P450 Inhibitors?
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Isoniazid
Sulfonamides Cimetidine Ketoconazole Erythromycin Grapefruit juice |
