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21 Cards in this Set
- Front
- Back
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How long does it take for antidepressant/antipsychotic to start working?
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up to a month before effects can be noticed
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For what conditions are antipsychotic meds contraindicated?
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-Liver damage
-CAD/CV disease -bone marrow depression -severe hypo/HTN -coma |
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Where does schizophrenia result from?
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dysfunction of dopaminergic, serotonergic, and neurotransmission systems in the brain
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How does pntipsychotics exert their effects?
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by decreasing dopamine activity and re-regulate abnormal neurotransmission systems
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What is the prototype drug of antipsychotics?
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Thorazine (phenothiazines)
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What is the prototype nonphenothiazine?
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Clozapine
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What does risperidone do?
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-block dopamine/serotonin
-can cause tardive dyskensia (lack of movement) |
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What is Abilify used for?
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-for schizophrenia and bipolar disorder
-Very expensive |
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Invega is given how often?
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Once a month
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Goals of antipsychotic treatment?
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-Alleviate symptoms (no cure)
-inc. ability to cope/socialize -promote fx of ADL's |
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What is haldol used for?
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-excess movement
-help with tourettes and huntingtons chorea (large, involuntary movements) |
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What are some extrapyramidal symptoms? (excess movement)
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-Akathesia (cant sit still)
-parkinsonism (shakes and tremors) -Dyskinesias (involuntary movement) -Tardive Dyskinesia (bizarre movements) |
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When do you administer phenothiazine antipsychotics?
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1-2 hrs before bed ~ peaks 2H after given
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Most common mental illness?
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-Depression
-5-10% of adults |
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How does antidpressant drugs work?
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By inhibiting the reuptake of norepi by the presynaptic terminal
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Where is the problem found with antidepression?
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synaptic receptors have changed, not the neurotransmitters
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Groups of antidepressant drugs?
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-TCA (tricyclic acid)
-MAO's (monoamnine oxidase) -SSRI's (selective serotonin reuptake inhibitor) |
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Contraindications for using antidepressants?
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-acute schizophrenia
-mixed mania and depression -suicidal tendencies -severe renal, hepatic, or CV disease -narrow angle glaucoma (inc. IOP) |
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What is used to help with smoking cessation and anorexia?
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Wellbutrin
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What drug has priapism as one of its side effects?
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Trazadone (for sedation more than depression)
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What is lithium used for?
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-for bi polar disorder
-may have a metallic taste in mouth |
