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15 Cards in this Set
- Front
- Back
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Anticoagulant classes
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anti-thrombin III enhancers
K inhibitors Thrombin inhibitors Xa inhibitors |
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anti-thrombin III enhancers uses
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prophylaxis, treat thrombotic event
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anti-thrombin III enhancers AE
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HIT
osteoporosis |
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anti-thrombin III enhancers
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Heparin
LMWHs Dalte, Enoxa, Tinxaparin |
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Vitamin K inhibitor
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Warfarin
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Vitamin K inhibitor effects
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inhib activation of K-dependent clotting factors
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Vitamin K inhibitor AE
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extensive D-D interactions
Metabolized via CYP450 no green leafies Pregnancy (X) |
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Thrombin (IIa) inhibitor
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Argatroban
Dabigatran Bivalirudin Desiruden Lepirudin |
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Thrombin (IIa) inhibitor effect
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inhibits bound or free thrombin, effects V,VIII,XIII,C,Fibrin
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Factor Xa Inhibitors
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For clot prevention post-op
Fondaparinux Rivaroxiban |
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Factor Xa Inhibitors MOA
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anti-thrombin III
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Factor Xa Inhibitors AE
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Thrombocytopenia
Liver enzyme increase |
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TPA
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Thrombolytics to treat embolic stroke
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TPA drugs
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Alteplase
Reteplase Streptokinase Tenecteplase Urokinase |
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TPA MOA
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increases conversion of plasminogen to plasmin which initiates fibrinolysis
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