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41 Cards in this Set

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Primaquine
4. Malaria profylaxis 5. Used for extraerythrocytic forms Plasmodium vivax or P. ovale Ciporfloxacin 6. Quinolone derivative
Sulfonamides
7. PABA structural analogs 8. Inhibit Folic acid synthesis
Tertacyclines, anuria & the exception
9. Should not be used in anuric pt due to production of (-) Nitrogen balance & inc.d BUN levels. 10. Doxycycline is the exception
Ceftriazone
11. 3rd generation cephalosporin 12. DOC for bacterial meningitis in kids (ie… HiB) 13. One dose txt of gonorrhea
Hepatic coma DOC
14. Neomycin (aminoglycoside) – it supresses the normal flora = dec.g NH4 production = dec.g free nitrogen levels in the bloodstream.
Clavulanic acid
15. Irreversible (-)r of â lactamases, but ot of transpeptidase = use w/ a â lactamase sensitive penicillin
Piperacillin
16. Txt Pseudomonas aeruginosa & Klebsiella 17. Broad spectrum antibiotic
Streptomycin (aminoglycoside)
18. Txt Mycobacterium tuberculosis
Isoniazid
19. Most commonly used drug for TB. 20. Usually combined w/ Rifampin and/or Ethambutol 21. Pre Txt w/ Pyridoxine (Vit B6) can prevent peripheral neuritis‘
Pyrantel Pamoate
22. Txt of Hookworm disease23. Depolarizing NMJ (-)r
Buy “AT” 30, “CELL” at 50
24. A = Aminoglycosides 25. T = Tetracyclines 26. C = Chloramphenicol 27. E = Erythromycin (macrolide) 28. L = Clindamycin 29. L = Lincomycin
Cefoxitin
30. Txt intraabdominal infections (ie… w/ Bacteroides fragilis) 31. Traditional txt has been Clindamycin & Gentamycin
Chloramphenicol
32. Broad spectrum antibiotic 33. Bone marrow depression (common) – Aplastic anemia (rare) 34. Gray baby syndrome (chloramphenicol cannot be conjugated) 35. DOC Typhoid Fever (symptomatic Salmonella infection) 36. DOC HiB meningitis in kids – especially resistant strain to ampicillin
Nifurtimox
37. Txt trypanosomiasis
Metronidazole 3
8. Txt Leishmaniasis & Amebiasis 39. Good for anaerobic bacteria = Bacteroides fragilis 40. DOC Trichomoniasis 41. DOC Giardia lamblia
Txt P. carinii
42. TMP-SMX & Pentamidine
Tetracycline
43. Txt of Brucellosis & Cholera 44. Txt Rocky Mountain Spotted Fever 45. Txt spirochete infections = Lyme disease (Borrelia burgdorferi)
TMP-SMX
46. (-) dihydrofolate reductase activity
Benzathine Penicillin G
47. Long duration of action = given once every 3-4 weeks for Txt of Syphilis
Praziquantel
48. Txt Schistosomiasis (trematode [fluke] infections)
Melarsoprol
49. Txt Trypanosomiasis that has neurological symptoms
Stibogluconate
50. Txt Leishmaniasis
Fluconazole
51. Txt fungal encephalitis
Amphotericin B
52. Polyene antifingal
Ketoconazole MOA
53. (-) fungal ergosterol synthesis = disrupts membrane
Griseofulvin MOA
54. Accumulates in keratinized layers of the skin = used in dermatomycoses infections
Mefloquine
55. Anti malarial 56. Txt Chloroquine resistant strains = P. falciparum
Chloroquine
57. Txt for Malaria when inside RBC
Nifurtimox
58. DOC Chagas disease due to Trypanosoma cruzi
Erythromycin
59. Used in pts allergic to penicillins
Nystatin
60. Topical txt of superficial mycotic infections = Candidiasis
Acyclovir
61. Guanine analog 62. Txt Herpes infections
Imipenem
63. Used w/ Cilastatin 64. Can cause seizures
Cefoperazone side effects
65. Bleeding due to vit K level alterations 66. Contraindicated in pts w/ bleeding disorders
Vancomycin
67. Used for MRSS (methicillin resistant Staph. Aureus) 68. “Red neck”: due to histamine release causes facial flushing
Meropenem
69. used w/ Cilastatin 70. Does not cause seizures (cf w/ Imipenem)
Nafcillin
71. Only penicillin that does not need dose adjustment in renal impairment
Peripheral neuropathy
72. Seen w/ use of: 73. Metronidazole – Isoniazid – Vincristine – ddI – AZT – Allopurinol
Sulfonamides & newborns
74. Kernicterus can occur
“O.N.E.” for gonorrhea
75. Fluoroquinolones used in a one dose deal for gonorrhea: 76. O = Ofloxacin 77. N = Norfloxacin78. E = Enoxacin
Ribavirin
79. Txt RSV (Respiratory Syncytial Virus)