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41 Cards in this Set
- Front
- Back
Primaquine
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4. Malaria profylaxis 5. Used for extraerythrocytic forms Plasmodium vivax or P. ovale Ciporfloxacin 6. Quinolone derivative
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Sulfonamides
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7. PABA structural analogs 8. Inhibit Folic acid synthesis
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Tertacyclines, anuria & the exception
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9. Should not be used in anuric pt due to production of (-) Nitrogen balance & inc.d BUN levels. 10. Doxycycline is the exception
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Ceftriazone
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11. 3rd generation cephalosporin 12. DOC for bacterial meningitis in kids (ie
HiB) 13. One dose txt of gonorrhea
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Hepatic coma DOC
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14. Neomycin (aminoglycoside) it supresses the normal flora = dec.g NH4 production = dec.g free nitrogen levels in the bloodstream.
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Clavulanic acid
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15. Irreversible (-)r of â lactamases, but ot of transpeptidase = use w/ a â lactamase sensitive penicillin
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Piperacillin
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16. Txt Pseudomonas aeruginosa & Klebsiella 17. Broad spectrum antibiotic
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Streptomycin (aminoglycoside)
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18. Txt Mycobacterium tuberculosis
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Isoniazid
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19. Most commonly used drug for TB. 20. Usually combined w/ Rifampin and/or Ethambutol 21. Pre Txt w/ Pyridoxine (Vit B6) can prevent peripheral neuritis
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Pyrantel Pamoate
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22. Txt of Hookworm disease23. Depolarizing NMJ (-)r
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Buy AT 30, CELL at 50
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24. A = Aminoglycosides 25. T = Tetracyclines 26. C = Chloramphenicol 27. E = Erythromycin (macrolide) 28. L = Clindamycin 29. L = Lincomycin
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Cefoxitin
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30. Txt intraabdominal infections (ie
w/ Bacteroides fragilis) 31. Traditional txt has been Clindamycin & Gentamycin
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Chloramphenicol
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32. Broad spectrum antibiotic 33. Bone marrow depression (common) Aplastic anemia (rare) 34. Gray baby syndrome (chloramphenicol cannot be conjugated) 35. DOC Typhoid Fever (symptomatic Salmonella infection) 36. DOC HiB meningitis in kids especially resistant strain to ampicillin
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Nifurtimox
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37. Txt trypanosomiasis
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Metronidazole 3
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8. Txt Leishmaniasis & Amebiasis 39. Good for anaerobic bacteria = Bacteroides fragilis 40. DOC Trichomoniasis 41. DOC Giardia lamblia
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Txt P. carinii
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42. TMP-SMX & Pentamidine
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Tetracycline
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43. Txt of Brucellosis & Cholera 44. Txt Rocky Mountain Spotted Fever 45. Txt spirochete infections = Lyme disease (Borrelia burgdorferi)
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TMP-SMX
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46. (-) dihydrofolate reductase activity
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Benzathine Penicillin G
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47. Long duration of action = given once every 3-4 weeks for Txt of Syphilis
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Praziquantel
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48. Txt Schistosomiasis (trematode [fluke] infections)
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Melarsoprol
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49. Txt Trypanosomiasis that has neurological symptoms
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Stibogluconate
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50. Txt Leishmaniasis
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Fluconazole
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51. Txt fungal encephalitis
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Amphotericin B
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52. Polyene antifingal
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Ketoconazole MOA
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53. (-) fungal ergosterol synthesis = disrupts membrane
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Griseofulvin MOA
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54. Accumulates in keratinized layers of the skin = used in dermatomycoses infections
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Mefloquine
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55. Anti malarial 56. Txt Chloroquine resistant strains = P. falciparum
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Chloroquine
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57. Txt for Malaria when inside RBC
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Nifurtimox
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58. DOC Chagas disease due to Trypanosoma cruzi
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Erythromycin
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59. Used in pts allergic to penicillins
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Nystatin
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60. Topical txt of superficial mycotic infections = Candidiasis
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Acyclovir
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61. Guanine analog 62. Txt Herpes infections
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Imipenem
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63. Used w/ Cilastatin 64. Can cause seizures
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Cefoperazone side effects
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65. Bleeding due to vit K level alterations 66. Contraindicated in pts w/ bleeding disorders
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Vancomycin
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67. Used for MRSS (methicillin resistant Staph. Aureus) 68. Red neck: due to histamine release causes facial flushing
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Meropenem
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69. used w/ Cilastatin 70. Does not cause seizures (cf w/ Imipenem)
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Nafcillin
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71. Only penicillin that does not need dose adjustment in renal impairment
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Peripheral neuropathy
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72. Seen w/ use of: 73. Metronidazole Isoniazid Vincristine ddI AZT Allopurinol
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Sulfonamides & newborns
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74. Kernicterus can occur
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O.N.E. for gonorrhea
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75. Fluoroquinolones used in a one dose deal for gonorrhea: 76. O = Ofloxacin 77. N = Norfloxacin78. E = Enoxacin
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Ribavirin
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79. Txt RSV (Respiratory Syncytial Virus)
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