Pharm Abx Moa And Mor

Front 1

What are the four major MOA of ABX?

Back 1

1. Inhibitors of Bacterial cell wall synthesis
2. Inhibitors of bacterial protein synthesis
3. Inhibitors of Nucleic acid synthesis
4. Inhibitors of Folic Acid synthesis

Front 2

What are the Inhibitors of Bacterial cell wall synthesis?(5)

Are they cidal or static?

Back 2

1. PCNs
2. Cephalosporins
3. Vancomycin
4. Imiprenim/Meroprenum
5. Aztreonam

1. Cidal

Front 3

What are the inhibitors of Bacterial Protein synthesis?(6)

Are they cidal or static?

Back 3

1. Aminoglycosides
2. Tetracyclins
3. Macrolides
4. Chloramphenicol
5. Linezolid
6. Steptogrammins

1. Static

Front 4

What are the inhibitors of nucleic acid synthesis?(2)

Back 4

1. Flouroquinilones
2. Rifampin

1. Static

Front 5

What are the inhibitors of Folic Acid synthesis?(3)

Cidal or Static?

Back 5

1. Sulfonamides
2. Trimethoprim
3. Pyromethamine

1. Static

Front 6

What are the bacterial MOR of PCN and Cephalosporins?(3)

Back 6

1. Beta Lactamase
2. Change in PBP structure
3. Change in Porins

Front 7

What are the bacterial MOR of Aminglycosides?

Back 7

1. Enzymes/Proteins that bind to the drug to inactivate it

Front 8

What are the bacterial MOR of Macrolides?

Back 8

1. Change the 50S binding site using methyltransferases

Front 9

What are the bacterial MOR of Tetracyclines?

Back 9

1. Insert Efflux pumps

Front 10

What are the bacterial MOR of Sulfonamides?

Back 10

1. Increase the amount of substrate (PABA)

Front 11

What are the bacterial MOR of Flouroquinalones?

Back 11

1. Insert efflux pumps

Front 12

What are the bacterial MOR of Chloramphenicol?

Back 12

1. Acetyltransferases that inactivate the drug