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22 Cards in this Set
- Front
- Back
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4th generation cephalosporins
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Cefepime [the only FDA approved 4G cephalosporin, cef-UH-peem]
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Atypical pneumonia DOC
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Macrolides (1st: Doxycycline, 2nd: FQ)
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Chloramphenicol MOA
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50S protein synthesis inhibitor
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DOC & 2nd line for meningococcal meningitis
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Pen G DOC, Ceftriaxone (3G Cephalo)
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Daptomycin MOA
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Depolarizes G+ cell membrance, bacteriocidal, concentration dependent
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Daptomycin is not good for what type of infections?
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Pneumonia [binds surfactant], Meningitis [does not cross BBB], G- [only works on G+]
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Describe DTP Vaccine
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Formalin inactivated, booster required every 10 years, Pertussis portion is usually acellular (DTaP) for safety
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Hib Tx and Prophylaxis
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HiB Tx is ceftriaxone, HiB prophylaxis is Rifampin; vaccination is good too
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List the Macrolides & MOA
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Azithromycin, Clarithromycin, Erythromycin; bind 50S
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Macrolide MOA
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50S inhibitors
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Macrolide stem
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-thromycin
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PCP Tx & prophylaxis
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TMP-SMX for prophylaxis, Pyrimethamine & Sulfadiazine for Tx
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TB Treatment
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INH, rifampin, pyrazinamide, & ethambutol [pure-a-zin-amide & etham-butol]
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Vancomycin Resistant Enterococcus Tx
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Linezolid or Streogramins (quinupristin/dalfopristin)
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What is the treatment for impetigo?
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Topical mupirocin or systemic first-generation cephalosporin.
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Which cephalosporins are good for meningitis?
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Only 3G cephalosporins are good for meningitis
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Fluoroquinolone CIs
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Pregnant, breast feeding, or children under 18
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List Beta-lactamase inhibitors
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Clavulanic Acid, Subactam & Tazobactam
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Tetracycline CIs
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Pregnant, breast-feeding, children under 8, renally impaired (except Doxycycline)
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Aztreonam spectrum
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Aerobic Gram Negatives [ineffective against G+ and anaerobes]
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Daptomycin spectrum
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Gram Positive only, ineffective in pneumonia (inactived by surfactant) and does not cross BBB
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Listeria Tx 1st & 2nd
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1st amp, 2nd TMP-SMX
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