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5 Cards in this Set
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- Back
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TCA
amitriptyline HCl (elavil) Desipramin HCl (norpramin) Imipramine (tofranil) nortriptyline HCl (aventyl) protriptyline HCl (vivactil) maprotiline (ludiomil) |
AE: anticholinergic effects (dry mouth, blurred vision, C
sedation, slowing, poor concentration tachycardia, OHON, (assess for MI) N/V **narrow therapeutic index** admin HS 2-6 weeks b4 effect 1-3 weeks b4/after MAO inhibitor avoid etoh avoid HTN meds |
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MAOI
isocarboxazid (Marplan) phenelzine sulfate (Nardil) tranylcypromine sulfate (Parnate) |
use: depression, phobia, anxiety
AE: ^HR, impotence, dizzy, muscle twitch, drowsy, dry mouth, **don't use with TCA** dietary restriction (avoid HTN crisis) -high tyramine: aged cheese, red wine, beer, beef and chicken, liver, yeast, yogurt, soy sauce, chocolate, bananas s/sx HTN crisis: HA, palpitations, ^BP |
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SSRI
Fluoxetine (Prozac) Paroxetine (Paxil) Sertraline (Zoloft) Fluvoxamine (Luvox) Citalopram (Celexa) Escitalopram (Lexapro) |
use: depression, anxiety, panic Do, aggression, Anorexia, OCD
***don't use with MAOI--> HTN crisis wait 14 days after MAOI to start Prozac and 5 weeks after Prozac to restart MAOI HS if sedation occurs Serotonin syndrome s/sx: rapid AMS, agitation, myoclonus, hyperreflexia, fever, shivering, diaphoresis, ataxia, diarrhea **don't use St. John's Wort |
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Newer antidepresants (atypical)
trazodone (Desyrel) Mitrazpine (Remeron) Bupropion (Wellbutrin) |
use: depression
safer than MAOI/TCA 2-4weeks b4 tmt |
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Serotonin/norepinepherine reuptake inhibitor
Duloxetine (Cymbalta) Venlafixine (Effexor) |
use: depression, anxiety, panic Do, aggression, Anorexia, OCD
*don't w/drawal suddenly Dont' use with MAOI (wait 14 days post to admin new med) monitor BP |
