Pharm

Front 1

If a patient is prescribed clopidogrel what should they be tested for and why?

Back 1

CYP2C19

its a 'prodrug' and has to be activated by allele

Front 2

ACh is synthesized from what?

Back 2

choline and acetylCoA

Front 3

NE is synthesized from what?

Back 3

tyrosine by the enzyme tyrosine hydroxylase

Front 4

Secretions are what?

Back 4

cholinergic

(parasympathetic)

Front 5

muscarinic antagonists compete with what?

Back 5

ACh

Front 6

Describe the agonist dobutamine

Back 6

B1 selective

for shock & heart failure

Front 7

Describe the agonist phenylephrine

Back 7

a1 selective

nasal decongestant

Front 8

Describe the agonist clonidine

Back 8

a2 selective

antihypertensive (works in CNS)

Front 9

Describe the agonist Albuterol

Back 9

B2 selective

for asthma

Front 10

Describe the indirect acting agonist amphetamine

Back 10

releases NE by reversing transporter

Front 11

Describe the indirect acting agonist tyramine

Back 11

releases NE

Front 12

Describe the indirect acting agonist ephedrine

Back 12

combination agonist

releases NE

Front 13

Describe the alpha receptor antagonist phenoxybenzamine

Back 13

alkylates receptor

for phenochromocytoma

Front 14

Describe the alpha receptor antagonist phentolamine

Back 14

competitive

for phenochromocytoma

Front 15

Describe the alpha receptor antagonist prazosin

Back 15

a1 selective

for hypertension

Front 16

Describe the alpha receptor antagonist terazosin

Back 16

a1 selective

for benign prostatic hyperplasia

Front 17

Describe the beta receptor antagonist propranolol

Back 17

competitive

for hypertension and angina

Front 18

Describe the beta receptor antagonist timolol

Back 18

competitive

for glaucoma

Front 19

Describe the beta receptor antagonist antenolol and metoprolol

Back 19

B1 selective

for angina and hypertension

Front 20

Describe the beta receptor antagonist pindolol

Back 20

B1 selective

partial agonist

Front 21

Describe the antihistamine cetirizine

Back 21

H1 antagonist

for urticaria

Front 22

Describe the antihistamine cimetidine

Back 22

H1 antagonist

for GERD/ulcers

Front 23

Describe the Proton pump inhibitor (PPI) omeprazole

Back 23

covalent binding to H+ K+ ATPase to decrease H+ secretions (acid)

Front 24

Describe the antacid aluminum hydroxide

Back 24

weak base that neutralizes gastric acid

Front 25

Describe the mucosal protectant sulfacrate

Back 25

binds to epithelial cells and prevents acid damage

Front 26

Describe the medication used to regulate Asthma/COPD albuterol

Back 26

short acting B2 agonist

Front 27

Describe the medication used to regulate Asthma/COPD triamcinolone

Back 27

corticosteroid

decreases inflammatory cells

Front 28

Describe the medication used to regulate Asthma/COPD montelukast

Back 28

leukotriene receptor antagonist

Front 29

Describe the medication used to regulate Asthma/COPD cromolyn

Back 29

inhibits degranulation of mast cells

Front 30

Describe the medication used to regulate Asthma/COPD ipratropium

Back 30

muscarinic receptor antagonist

Front 31

Describe the medication used to regulate Asthma/COPD theophylline

Back 31

inhibits phosphodiesterases to increase cAMP

Front 32

Describe the medication used to regulate Asthma/COPD omalizumab

Back 32

decreases release of histamine