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10 Cards in this Set

  • Front
  • Back

Choline uptake is inhibited by

Hemicholinium

Prevents ACh release

Botulinum toxin

Reversible AChE Inhibitors

Edrophonium, Physostigmine, Neostigmine

Irreversible AChE Inhibitors

Echothiophate, Malathion, Parathion

Muscarinic (M1-5) receptor activations leads to

Decreased CV function


increase secreation


increase smooth muscle contraction

most common reported side effect of muscarinic agonists

excessive sweating


GI distress

Rivastigmine is used for

Alzheimer


Parkison

Donepezil is used for

Alzheimer



Signs of AChE poisioning

DUMBBELSS


Diarrhea


Urination


Miosis


Bradycardia


Bronchoconstriction


Lacrimation


Salivation


Sweating


CNS stimulation

Management of AChE poisioning

Mucarinic- Atropine


Regeneration of AChE- Palidoxime