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10 Cards in this Set
- Front
- Back
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PHARM 504: Neuroeffector Junctions I
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PHARM 504: Neuroeffector Junctions I
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Parasympathetic Nervous System
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Eyes: constriction of ciliary muscles and pupil.
Lungs: constriction of bronchi and trachea. Liver: decrease glycogenolysis Arteries & veins: decrease BP, and redistribution of blood flow to GI. |
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Parasympathetic nerves
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Long Pre: releases Ach
Short Post: also release Ach |
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Adrenal glands are innervated by?
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Preganglionic choinergic neuron--> at the chromaffin cells--> release EPI.
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How does EPI behave as?
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As a hormone moreso than a neurotransmitter.
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Effect of sympathetic on vessels?
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Constriction--> inc BP
while parasym causes DILATION reducing BP. |
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What receptors does ACh activate?
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1. nicotinic
2. muscurinic |
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What receptors does NE activate?
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1. alpha
2. beta |
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In the parasympathetic nerves, what receptors are involved and where?
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Nicotinic receptors: are cholinergic receptors that form ligand-gated ion channels in the plasma membranes of certain neurons and on the postsynaptic side of the neuromuscular junction
Muscarinic receptors: stimulated by acetylcholine released from postganglionic fibers in the parasympathetic nervous system. |
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In the sympathetic nerves, what receptors are involved and where?
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Nicotinic
Adrenergic (postgang terminal end): a class of G protein-coupled receptors that are targets of the catecholamines, especially noradrenaline (norepinephrine) and adrenaline (epinephrine). |
