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7 Cards in this Set

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  • Back
Diphenhydramine
-Class: 1st Generation Anti-Histamine
-Therapeutic Use: Tx of H1-mediated allergic response (possible local anesthetic?)
-Important Side Effects: anti-cholinergic like effects, +++ Sedation
-Important Interactions: Paradoxical Stimulation in Children
Chlorpheneramine
-Class: 1st Generation Anti-Histamine
-Therapeutic Use: Tx of H1-mediated allergic response
-Important Side Effects: Anti-cholinergic like effects, +++ Sedation
-Important Interactions: Paradoxical stimulation in children
Promethazine:
-Class: D2 Antagonist – Phenothiazine antipsychotic
-Therapeutic Use: used as an Anti-emetic (anti-nausea and vomiting) (possible anesthetic)
-Important Side Effects: Hyperprolactinemia and EPS
-Important Interactions: Synergistic w/ CNS depressants
Fexofenadine:
-Class: 2nd Generation Anti-Histamine (Terfenadine is metabolized to form Fexofenadine)
-Therapeutic Use: Tx of H1-mediated allergic responses
-Important Side Effects: Some anti-cholinergic effects, + sedation.
-Important Interactions: few
Cetirizine:
-Class: 2nd Generation Anti-Histamine (Hydroxyzine is metabolized to form Cetirizine)
-Therapeutic Use: Tx of H1-mediated allergic response
-Important Side Effects: some anti-cholinergic effects, + sedation
-Important Interactions: synergistic effects w/ CNS depressants
Loratadine:
-Class: 2nd Generation Anti-Histamine
-Therapeutic Use: Tx of H1-mediated allergic response
-Important Side Effects: some anti-cholinergic effects, + sedation
-Important Interactions: few
Azelastine:
-Class: Nasal Anti-Histamine
-Therapeutic Use: Allergic Rhinitis
-Important Side Effects: Drowsiness and Sedation (headache, dry mouth, weight gain)
-Important Interactions: few