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29 Cards in this Set
- Front
- Back
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OD treated with sodium bicarb
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weak acids
-aspirin |
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OD treated with ammonium chloride
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weak base
-amphetamines |
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MOA inhibits alcohol DH
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fomepizol
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MOA inhibits acetaldehyde DH
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disulfiram
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med ending in:
-azine |
phenothiazines
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med ending in:
-tropin |
pituitary hormone
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med ending in:
-operidol |
neuroleptics
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med ending in:
-phylline |
methylxanthine
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med ending in:
-terol |
B2 agonist
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what is pKa
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pH at which the amount of protonated equal non-protonates
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what happens when pH is less than pKa
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basic drugs get trapped
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what happens with pH is more than pKa
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acidic drugs get trapped
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eliminates linearly
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zero order
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eliminates exponentially
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first order
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elimination associated iwth half life
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first order
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drugs a.w zero order
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phenytoin
ethonal aspirin |
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which phase uses p450
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first
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which phase uses conjugation
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second
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which is lost in geriatric px
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first
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fomepizole is the antidote for what
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methonal
ethylene glycol |
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antidote for methonal
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ethonal
fomepizole |
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causes disulfiram rxn
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1st gen sulfonureas
cephalosporins carbazepine metronidazole procarbazine |
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toxic metabolite of:
ethylene glycol |
oxalic acid
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toxic metabolite of:
methonal |
formaldehyde
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toxic metabolite of:
ethonal |
acetaldehyde
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toxicity symptoms of:
methonal |
acidosis
retinal damage |
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toxicity symptoms of:
ethonal |
nausea
vomiting headache hypotension |
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toxicity symptoms of:
ethylene glycol |
acidosis
nephrotoxicity |
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px seen with a glow after drinking
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polymorphism in the gene that codes for acetaldehyde DH
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