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51 Cards in this Set

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Trizolam

Halcion, Short Acting 2-4H

Triad and H(alcion)iland

Midazolam

Versed, Short Acting, 1-2H


No Oral dosing

Mid(azolam)-verse(d)

Lorazepam

Ativan, Intermediate acting, 6-8H

Loraz in A-van

Alprazolam

Xanax, mid-long HL, 6-8H

Al(fred) with (X)an-AX

Diazepam

Valium (Oldest BZD), Longest HL (33H), 6-8H


Treatment of choice for lidocain induced seisures

Diaz gets valet

Zolpidem

Ambien, BZD like drug (but acts differently), Gaba-A agonist

Zol p(er)i-dem (62 Sports)

Phenobarbital

Treatment for seisures


Barbital (barbituate), Pheno

Thiopental

Induction for anesthesia, barbituate (tal)

Thio Epstine will induce anesthesia of Cubs

Chloral Hydrate

Used in pedo with H1 antag.


Low TI

Ch(ild)loral, H(H1antag)ydrate

Diphenhydramine

Benadryl H1R: Allergies, Motion sickness, and insomia

Hydroxyzine

Vistaril, H1R antag.: Selective Anxiolytic, and anti-emetic.


Causes Xerostomia

Zing,,,,zing,,,zing,,,zing


H1 Hummer

Buspirone

Buspar, selective anxiolytic, minimal sedation or CNS depression. Triggers 5HT1A receptors (serotonin)

Bus: Slow titrating, Pie: Serotonin, Non-sedating

Endorphins, Endomorphins, Enkelphalins, and Dynorphins

Endorphins: POMC


Endomorphins: CNS (pain)


Enkephalins: adrenal/CNS


Dynorphins: adverse opoids

Endorpnins: POMC


Endomorph: (become painful)


Enkephalins: keph=ceph=cns/adr


Dynorphins: Dyno=bad opoids

List the Opiates

Morphine, Codeine, Heroin

Dihydrocodeine

Similar strength to codeine

Oxycodone

High dependency


Oxycontin: sustained release


Stronger than Morphine

Hydrocodone

Similar strength to morphine

Give the strengths of opiates in ascending order

Codein=Hydrocodeine<Morphine=Hydrocodone<Oxycodone<Fentanyl

Fentanyl

80x more potent than morphine


Transdermal patch


Very Lipophilic


good analgesia/bad anesthesia

Daniel Fentalyn was potent!

Meperidine

Demerol


Bad interraction w/ MAOI,SSRI, TCA


Me in Perio Die: Life threatening interactions, Bad w/ TCA/SSRI

Tramadol

Ultram


Centrally acting, bind to mu-opoid


Can produce dependence


Less potent than morphine

Tram's use opoid's and SSRI's and die.....

Propoxyphene

Withdrawn due to MI/arrhy risk

Proxy, aka removed Ip address

Loperamide

used to tx diarrhea

Loper's when pooping

Dextromethorphan

Cough suppressant

Orphans get Whooping Cough

Naloxone

Treat overdose of opoid (antagonist)

OXO: IV, treat overdose of Opoid

Naltrexone

Oral, tx opoid toxicity (longer duration),

T-rex ate (oral)

Pentazocine

Mu/Delta antagonist, Kappa antagonist


Mixed acting

repent of zo sin fraternities!

Buprenorphine

Partial Mu/Delta antagonist


heroin/morphine antagonist

Hey Bu: Mixed antagonist

Propionic acid derivatives?

Ibuprofen


Naproxen (longer H/L)

PropIonic A.....IA.....Ib....Ibuprofen, Naproxen

Indole and Indene Derivatives

Indomethacin:


Etodolac

Pyrrole Derivatives

Ketorolac


Diclofenac

Indomethacine

More potent than ASA/ibuprofen, more side effects

Etodolac

Acetic acid derivative

Ketorolac

More potent than ASA/ibuprofen, bad side effects.


First injectable NSAID

Diclofenac

Combo with Misoprostol

Cox 2 Selective drugs

Celecoxib

Celecoxib

Fewer GI problems, manage RA/OA

Acetominophen

Antidote: N-acetylcycsteine

Naproxen:

Alieve: Long H/L, Good compliance (less dosing)

What drugs are used to treat gout?

Probenicide, allopurinol, colchicine

Halothane

Hepatotoxic, malignant hyperthermia,

Grandpa (Halo b/c angle) of Inhalation anesthesia

Enflurane

2-10% metabolized by liver


less hepatotoxic than halothane


Nephrotoxicity, convulsions

Flu: convulsions, nephrotoxicity

Isoflurane

Not hepato or nephro toxic


Sevoflurane

Rapid onset/recovery


Maintenance of anesthesia


Highly fluorinated

Stevo: Rapid onset/recovery

Methohexital

Barbituate


Common in dentistry


GABA-A activity

tal: barbituate


Hex: IV

Ketamine

non-competative NMDA


Dissociateive amnesia

Kettamin is NMDA and Diss. Amnesia

Propofol:

Non-barbituate, non-opoid. GABA-A agonist. Oil in water emulsion

Pro(pofol)tein binding

Fentanyl:

IV anesthesia


Fast onset/ short duration, poor anesthetic

Alfentanil

quick onset, short duration action

Ramifentanil

Same as alfentanil

Promethazine:

H1 antagonist, similar to diphenhydramine