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81 Cards in this Set
- Front
- Back
ACE-I Side Effects
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cough
Hyperkalemia hypotension Renal dysfxn angioedema |
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ARBs
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valsartan, losartan
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ARB Side Effects
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Similar to ACE-I but less severe
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Selective Beta Blockers
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Metoprolol and Atenolol
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Non-Selective Beta Blockers
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Propanolol
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Beta Blockers Side Effects
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Fatigue
Bronchospasm Bradycardia Withdrawal syndrome with discontinuance Sleep disturbance |
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Dihdropyridines
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Amlodipine, Nifedipine
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Non-Dihydropyridines
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Verapamil, Diltiazem
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Calcium Channel Blockers - Side Effects
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Edema
Dizziness Worsened heart failure Low blood pressure Rash |
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Indications for ACEIs
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HTN, CHF, post MI
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Contraindications for ACEIs
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Pregnancy, renal dysfxn
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Indications for ARBs
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HTN, CHF, pts who can't tolerate CAPTOPRIL COUGH
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Contraindications to ARBs
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Pregnancy
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ARBs have _________ effect on bradykinin levels so produce ____________ vasodilation as ACEIs
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NO, less
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Indications for Beta Blockers
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HTN
CHF Tachyarrhythmias, Afib, Aflutter, angina and MI |
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Contraindications to Beta Blockers
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Asthma
2nd* heart block bradycardia Acute HF |
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Beta Blocker Side Effects
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Hypotension,
CHF Asthma Bradycardia and Heart block Raynauds Impotence |
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Causes Rebound Tachycardia with abrupt D/C
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beta blockers
|
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Non-DHP Indications
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Stable Angina,
Sinus Tachy, Atrial Tachy, Reentrant Tachy HTN |
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DHP Indications
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HTN
Prinzmental Angina Cerebral a spasm |
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Non-DHP Contraindications
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WPW
Hypotension Acute CHF AV blocks |
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DP Contraindications
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Pregnancy
CAD |
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Non-DHP Side Effects
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Bradycardia
HF Hypotension |
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DHP Side Effects
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Vasodilation
Dizziness HA Tachycardia |
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____ have greater selectivity for vasculature than the __________
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DHPs, Non DHPs
|
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Renin Inhibitor
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Aliskiren
|
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Aliskiren Indications
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HTN
|
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Aliskiren Contraindications
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Pregnancy
|
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Aliskiren Side Effects
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Diarrhea
Angioedema |
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Statins - Indications
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1st line for hyperlipidemia
|
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Statin - Contraindications
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Pregnancy
|
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Statin - Side Effects
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Myalgias
Myositis Rhabdomylosis |
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Bile Acid Sequestrants - Example
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Cholestyramine
|
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Bile Acid Sequestrants have a high number of ______ _____________
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drug interactions
|
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Bile Acid Sequestrants - Side Effects
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GI
Hyperchloremic Acidosis |
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Fibrates - Example and indications
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Gemfibrozil
Dyslipidemia |
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Fibrates - Contraindications
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Renal or hepatic failure
|
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Fibrates - Side Effects
|
Rash
GI (cholelithiasis) Hepatic Pancreatitis Myositis |
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Class I anti-arrhythmics - examples & main MOA
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Sodium Channel Blockers
1a: procainamide, quinidine 1b: Lidocaine 1c: Flecainide |
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Indication for Procainamide or quinidine
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Atrial and Ventricular arrhythmia
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Indication for Lidocaine
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Ventricular arrhythmia
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Indications for Flecainide
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Afib
|
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Class 1 side effects
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Pro-arrhythmics
Nervous system dysfunction |
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Quinidine interacts with ______________
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Digoxin
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First line drug for Vfib and Vtachy is __________
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Amiodarone
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Class II anti-arrhythmic. Main MOA and examples
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Depression of SA Node - Slows tachys
Depression of AV node - protects ventricles in Afib and Aflutter. Beta Blockers |
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Class III anti-arrhythmic. Main MOA and examples
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Potassium Channel Blockers - Amiodarone
|
|
Indications for Class III
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Acute tx & prevention of Afib, Aflutter, Vfib and Vtach
|
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Class III Contraindications
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Hypotension
2nd and 3rd* heart block |
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Class III antiarrhythmic Side Effects
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Bradycardia,
heart block, hypotension |
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Class IV anti-arrhythmic examples
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Non-DHPs: Diltiazem, verapamil
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Adenosine - Indications
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Dx and Tx of SVTs
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Adenosine - Side Effects
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Dyspnea
Angina Nausea Transient complete heart block VERY SEVERE BUT TRANSIENT ~3 mins |
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_________ blocks the effects of adenosine
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Caffeine
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Cardiac Glycoside: Example and 2 Main MOAs
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Digoxin. 1 Inotropic action and Increased parasympathetic activity
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Digoxin Indictations
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CHF (3rd line in adults, 1st in children)
Afib |
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Digoxin Side Effects
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GI,
CNS CV (arrhythmias and heart block) orange tinted vision |
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Treatment for digoxin toxicity
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Digibind
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Anticholinergics - Examples
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Atropine
Scopolamine |
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Anticholinergic Indications
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Sinus Bradycardia
Tx of anticholinesterase side effect |
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Anticholinergics Side Effects
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Tachycardia
Dry Mouth |
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Atropine Overdose
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Red
Hot Dry Confused |
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Nitrates - Nitro Indications
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Stable Angina
Acute Coronary Syndroms |
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Nitrates Contraindications
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Hypotension
Coadministration with PDE 5 inhibitors (viagra) |
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Nitro Side Effects
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HA
Flushing Ortho hypotension syncope |
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Steroids Examples
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Prednisone
Methylprednisone Dexamethasone |
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Beta 2 Agonists - Examples (short and long acting)
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Short Acting
Albuterol Levalbuterol Long Acting Salmeterol |
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Beta 2 Agonists
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Tachycardia
Palpitations Tremor Hypokalemia Hyperglycemia |
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Inhaled Anticholinergics
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Ipratropium
|
|
Inhaled Anticholinergics - Side Effects
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Minimal 2* to low systemic absorption
dry mouth nasal irritation nose bleeds |
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Leukotriene Receptor Antagonists - Example
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Montelukast
|
|
Montelukast Side Effects
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Churg Strauss Syndrome
|
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Methylxanthines - Examples
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Theophylline
|
|
Theophylline Contraindications
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Coronary Heart Disease
|
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Theophylline Side Effects
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HA
Insomnia Tremor Seizures Irrgeular Heart beat |
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Inhaled Corticosteroids - Examples
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Budesonide
Fluticasone |
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PDE5 Inhibitors - Examples
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Sildenafil
Tadalafil |
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PDE5 Inhibitor - Indications
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Erectile Dysfxn
Pulmonary HTN |
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PDE5 Inhibitor - Contraindication
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Renal Failure
NITRO!!! |
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PDE5 Inhibitor - Side Effects
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Flushing, HA, Hypotension
PRIAPISM Hearing and vision loss |
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Vascular Prostaglandins - Indications
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Pulmonary HTN
ARDS |