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35 Cards in this Set
- Front
- Back
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Advantages of aerosolized route of administration
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Immediate onset, directly to lungs, reduced side effects from systemic absorption, smaller dose, non invasive.
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Generic names of sympathomimetics
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Epinephrine, isoproteronol, isotherine, metaproterenol, terbutaline, bitolterol, albuterol, pirbuterol, salmeterol, levalbuterol,
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Which sympathomimetic is the strongest beta1 agonist
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Isoproteronol
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What breaks down 3,5 cAMP
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Phosphodiesterase
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Appropriate doses for ventolin
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0.25 - 0.5 cc in 2.5 cc in normal saline.
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Which bronchodilator has a pulmonary vasodilating effect?
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Isoproteronol
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Know metaproterenol
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Alupent, Metaprel
Dose: 0.2 - 0.3 cc Duration: 3-4 hours |
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Recommended breathing pattern for maximal deposition of aero meds
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Inhale slowly and hold at end of inspiration for 3 - 5 seconds
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Why use a space on an MDI
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Hold med in chamber and suspend medication
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If MDI floats on its side its
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empty
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Purpose of breath hold at end of inspiration during areo treatment
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Better absorbtion
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Primary goals of drugs that promote bronchodilation by relaxing smooth muscle by ______ Levels of ______
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Increasing, cAMP
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Which sympathomimetic is the strongest beta1 agonist
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Isoproteronol
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What breaks down 3,5 cAMP
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Phosphodiesterase
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other name for beta antagonist? other name for beta2 adrenergic
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parasympathomimetic / anti-anticholinergic
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proper sequence of instruction for activating and breathing for an MDI
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ativate MDI at beginning of inspiration, breath in fully and hold for 5 seconds
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Recommended flow range for SVN
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6-9 lpm for optimal time
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xanthines mech of action, how is drug administered
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inhibits function of phosphodiesterase increasing cAMP / IV, capsuls, tablets
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which "front door" is a strong alpha adrenergic agent
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sympathomimetic
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LVN diluents of choice
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?
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define bronchconstriction
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lumen of airway reduced due to bronchospasm, mucosal edema, or secretions
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know bland aerosoles
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?
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mech of action of NaHCO3
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increases sputum ph and destabalizes amino acid chains
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other names for Flunisolide
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Aerobid, bromolide
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biggest adverse effect of aerosolized steroids
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Adrenal suppresion
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pulmonary surfactant
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-phospholipid detergent that increases surface tension
-alveolar type 2 cells -Bovine(Beractant), Exosurf |
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know all alpha adrenergic drugs
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epinephrine(adrenaline), Isoproterenol(Isuprel), Isotherine(Bronkosol, Dilabron)Metaproterenol(Alupent, Metaprel), Terbutaline(bricanyl,brethine), Albuterol, Salmeterol, Levalbuterol, xopenex
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dose to administer for ethyl alcohol aerolized
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5-15 ml of 30-50% via SVN or IPPB
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name drugs that can used prophalaxis to treat asthma
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Cromylyn Sodium (Intal)
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Contra indications to administer surfactant replacement therapy
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NONE
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Surfactant is normally stimulated how
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stimulated by anything that normally activates the lungs stretch receptor ie: Sighing
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Why give steroids with BETA agonist
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to increase bronchdilation
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mech of action of Chromolyn Sodium
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prophylactic that stabalizes mast cell from breaking down
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advantages of aerolized steroids
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less serious side effects, no adrenal suppression, low risk of dependency, increase bronchodilation
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mast cell stabalizers (names of drugs)
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Steroids
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