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34 Cards in this Set
- Front
- Back
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What are the pros of partial opioid agonists
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low resp. depression
low potential for physical dependence |
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What are the cons of partial opioid agonists
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decreases effect of other opioid
dysphoric reaction |
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What are two reasons that butorphanol is used in OB
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Mu receptors are blunted in labor (stadol likes kappa)
Less resp. depression in neonate |
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Good drug for reducing respiratory depression without counteracting analgesic effects of opioids
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nalbuphine
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Agonist-antagonist that is not reversed with naloxone
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buprenorphine
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Naloxone onset and duration
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1-2 minutes
30-45 minutes |
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Where is butorphanol's site of action
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Kappa
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Why is butorphanol a good OB drug
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Works on Kappa
(mu receptors depressed in pregnancy) Low neonatal resp depression |
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Onset and duration of naloxone
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1-2 minutes
30-45 minutes |
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Partial agonist that can be used for biliary spasm
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nubain
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How do you treat someone with DTs
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BZD
Precedex |
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What are the benefits of using epinephrine when giving intrathecal injections
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prevents absorption into venous sinus plexus
spinal pain reliever |
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When you see N/V with spinal anesthesia, this usually indicates
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hypotension
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First sign of respiratory depression with intrathecal opioid admin
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somnolence
due to hypercarbia |
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VP sevo
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157
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VP Iso
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240
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VP Des
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669
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VP NO2
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38,770
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Solubility coefficient sevo
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0.65
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Solubility coefficient des
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0.42
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Solubility coefficient Iso
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1.46
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Solubility coefficient NO2
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0.46
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Which of the gases is most soluble
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Isoflurane
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Boiling point of sevo
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59
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Boiling point of des
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24
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Boiling point of Iso
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49
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Boiling point NO2
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-88
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What kind of analgesia do you want to administer to someone who is on Naltrexone
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Regional or gas
narcotics will cause N/V |
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When will you see respiratory depression from cephalad spread of intrathecal administration of lipophillic opioids
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after 2 hours
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When will you see respiratory depression from cephalad spread of intrathecal administration of morphine opioids
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after 2 hours
usually in first 12 hours possible up to 24 hours later |
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Most common sign of respiratory depression
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sleepiness because of hypercarbia
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What must you do after administering a morphine spinal
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write an order for the patient not to receive any more opioid
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Will positioning affect your intrathecal opioids
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nope
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where do neuraxial opioids act
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lamina 2, 3, 5
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