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11 Cards in this Set
- Front
- Back
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Alcohols
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CNS depressant
Ethanol Methanol Ethylene glycol Isopropyl alcohol |
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Barbiturates and Benzodiazepines
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Pentobarbital (‘downers’)
Flunitrazepam (Rohypnol, ‘roofies’) γ-hydroxybutyrate (‘GHB’) SE withdrawal: anxiety, insomnia, HTN, tachy, mm. twitches |
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Opioids
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Heroin (‘smack’, ‘H’)
Oxycodone (Oxycontin) SE withdrawal: vomiting and nausea, intense intestinal cramps, diarrhea, HR and BP increase, jerking TX: methadone, natrexone |
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Methamphetamine (meth)
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CNS Stimulant
less NE released than amphetamine, smoked, "tweeking" SE: toxic paranoid psychosis deaths due to cardiac arrhythmia and uncontrolled seizures |
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3,4 MDMA (ecstasy)
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CNS Stimulant
oral administration; club drug at ‘raves’ neurotoxic to serotonergic neurons SE: hyperthermia, cardiac arrhythmia, rhabdomyolosis, disseminated vascular coagulation |
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Cocaine (coke, crack)
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CNS Stimulant
MOA: blocks reuptake of NE, DA natural from coca plant smoked, snorted SE: cardiac arrhythmia and uncontrolled seizures |
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Caffeine (‘java’)
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CNS Stimulant
MOA: presynaptic adenosine receptor antagonist (increases dopamine release) increased mental alertness, anti-fatigue, mood elevation SE: ulcers, headache, fatigue, irritability |
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Nicotine (‘cancer stick’)
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CNS Stimulant
MOA: agonist at CNS nicotinic cholinergic receptors mild euphoria, increased arousal and concentration, improved memory, appetite suppression |
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Marijuana (‘weed’,’pot’, ‘grass’, ‘ganja’, ‘reefer’)
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Psychoactive drug
MOA: THC binds to GPCR called CB1 SE: dec. testosterone, lower birth weight, longer labor, malformation in offspring and learning deficits, schizophenia |
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Lysergic acid diethylamide (LSD, ‘acid’)
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Hallucinogen
one of most POTENT agents MOA: interaction at serotonin (5-HT) receptors SE: flashbacks (20 years later), "bad trip" (panic, loss of ego) no OD |
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Phencyclidine (PCP, ‘angel dust')
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Hallucinogen
MOA: binds to glutamate (NMDA) receptors as an antagonist slurred speach, ataxia, euphoria, violence SE: death from convulsions and coma no tolerance or dependence |
