Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
23 Cards in this Set
- Front
- Back
|
Alprazolam (Xanax)
|
Benzo
MOA: bind to GABAa1,a2 to open Na channel more frequenty, increase GABA inhibition Fast onset, medium duration Active metabolites Tx: Anxiety (panic disorder) MOC |
|
|
Diazepam (Valium)
|
Benzo-Fastest
MOA: bind to GABAa1,a2 to open Na channel more frequenty, increase GABA inhibition Fast-very fast onset, long duration Tx: Alcohol detox.; anxiety; M spasm; seizure; spasticity |
|
|
Triazolam (Halcion)
|
Benzo-Fastest
MOA: bind to GABAa1,a2 to open Na channel more frequenty, increase GABA inhibition Fast onset, short duration Tx: Insomnia (→ ↓CNS; dependence; ↓respiratory) |
|
|
Chlordiazepoxide (Librium)
|
Benzo-Slowest
MOA: bind to GABAa1,a2 to open Na channel more frequenty, increase GABA inhibition Fast-very fast(IV) onset, long duration Tx: Alcohol detox.; anxiety |
|
|
Flurazepam
|
Benzo-Slowest
MOA: bind to GABAa1,a2 to open Na channel more frequenty, increase GABA inhibition Fast onset, long duration Tx: Insomnia |
|
|
Chlorazepate
|
Benzo
MOA: bind to GABAa1,a2 to open Na channel more frequenty, increase GABA inhibition Prodrug, activated in stomach "chlora, hydrochloric" |
|
|
Clonazepam (klonopin)
|
Benzo
MOA: bind to GABAa1,a2 to open Na channel more frequenty, increase GABA inhibition Fast onset, medium duration. NO active metabolite. Tx: Anxiety (panic); seizure disorder |
|
|
Lorazepam (Ativan)
|
Benzo
MOA: bind to GABAa1,a2 to open Na channel more frequenty, increase GABA inhibition phase II conjugation) (safer in elderly) NO active metab Tx: Anxiety; seizures |
|
|
Oxazepam
|
Benzo
MOA: bind to GABAa1,a2 to open Na channel more frequenty, increase GABA inhibition phase II conjugation) (safer in elderly) NO active metab Tx: Anxiety |
|
|
Temazepam
|
Benzo
MOA: bind to GABAa1,a2 to open Na channel more frequenty, increase GABA inhibition phase II conjugation) (safer in elderly) NO active metab. Tx: Insomnia |
|
|
Amobarbital
|
Barb
MOA: bind to GABAa1,a2 to increase time Na channel is open, increase GABA inhibition Fast onset, medium duration NO active metab Tx: Insomnia |
|
|
Pentobarbital
|
Barb
MOA: bind to GABAa1,a2 to increase time Na channel is open, increase GABA inhibition Fast onset, short duration NO active metab Tx: Insomnia |
|
|
Phenobarbital
|
Barb
MOA: bind to GABAa1,a2 to increase time Na channel is open, increase GABA inhibition slow onset, long duration NO active metab Tx: Seizures |
|
|
Thiopental
|
Barb
MOA: bind to GABAa1,a2 to increase time Na channel is open, increase GABA inhibition very fast(IV) onset, short duration NO active metab Tx: Induction of anesthesia |
|
|
Diphenhydramine (Benadryl)
|
Antihistamine
MOA: binds H1 to decrease release of Ach Fast onset, medium duration NO active metab Tx: Insomnia |
|
|
Hydroxyzine
|
Antihistamine
MOA: binds H1 to decrease release of Ach Fast onset, long duration NO active metab Tx: Anxiety; sedation |
|
|
Ramelteon (Rozerem)
|
Melatonin Receptor agonist
Tx: Sleep onset insomnia (only) approved for LT use |
|
|
Eszopiclone (Lunesta)
|
Active stereoisomer of Zopiclone
MOA: binds BABA1a Na channel, increases GABA inhibition Tx: sleep-onset insomnia |
|
|
Zolpidem (Ambien)
|
MOA: binds BABA1a Na channel, increases GABA inhibition
Fast onset, short duration NO active metab Tx: Insomnia |
|
|
Zaleplon (Sonata)
|
MOA: binds BABA1a Na channel, increases GABA inhibition
Fast onset, very short duration NO active metab Tx: Insomnia |
|
|
Melatonin
|
Fast onset, medium duration
NO active metab Tx: Insomnia (jet lag) |
|
|
Buspirone (Buspar)
|
very slow onset, medium duration
MOA: partial agonist of 5HT1 (seratonin) NO active metab Tx: Chronic Anxiety can be used with depressants |
|
|
Propanolol
|
Fast onset, medium duration
Beta-Blocker Active metab Tx: Situational or performance anxiety |
