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49 Cards in this Set

  • Front
  • Back
3 types of partial seizures
simple and complex partial and 2nd generalized seizure
describe simple partial and duration
small focal- twitching thub, no LOC, and 20-60 seconds
describe complex
impaired LOC, 1st motionless and 2nd- automatism- purpuseless movements- 45 -90 sec
describe grand mal
tonic-clonic, urination, cry, and postictal state afterwords (CNS depression) 90
describe absence
petit mal- LOC staring, 10-30
how long to qualify for status epilepticus and dangerous type
30 min and generalized convulsive
4 ways AEDs work
supress Na and Ca, (reducing AP) GABA potentiation, andantag glutamate
use pheytoin for what
grand mal and partial(better stuff for these) but not absence
use ethosuximide for
absence but not grand mal or partial
use valproic acid for
all types of seizures
how is determining dosage for absence different?
use journaling and behaviour bc they happen so frequently like 100 times a day
how to stop AEDs
slowly 6 wks to several months
therapeutic blood levels for phenytoin and other name
dilantin, 10-20 narrow range
adverse for pheyntoin
nystagmus, diplopia, sedation (esp, ETOH), ataxia, gum swelling, preg-vit k, iv-hypo and dysrhythmia
other name for tegerol
carbamazepine
tegerol useful for
partial and grand mal not absense
compare tegerol to pheyntoin
tegerol has less side effects, less cognitive effects
adverse for tegerol
visual disturbances and ataxia but improves with time, leukopenia, anemia, and thrombocyto
s x s of hematologic effects of tegerol and wbc for leukopenia and prevention
3000, fever sore throat pallor infection petechiae bruising
blood counts before and after
which antiseizure is addictive
pheynlbarb
how to minimize reaction to phenytoin IV
go slowly
another name for valproic acid
depakote
depakote used for
all seizures, bipolar, migraines
adverse effect of depakote
pancreatitous and hepatotoxity
which antiseizure is addictive
pheynlbarb
how to minimize reaction to phenytoin IV
go slowly
another name for valproic acid
depakote
depakote used for
all seizures, bipolar, migraines
adverse effect of depakote
pancreatitous and hepatotoxity, increased ammonia, birth defects
signs of a liver problem
reduced appitette, N, lethargy, ab pain, jaundice
drug used for absence seizures - 2 names
ethosuximide and zarontin
how does Phenobarb work?
intensify GABA
what class is phenobarn in?
anticonvolsant barbituites
pheno used for
all seizures axcept absent
pheno adverse
Can cause nystagmus and ataxia in excessive doses.
sedation
which drugs can decrease Vit K clotting factors?and with pregnant women?
Phenobarbital, phenytoin, carbamazepine and primidone
Pregnant women should have K supplement, 10 mg/daily and baby 1mg at birth
carbamazepine interactions
warfarin and Oral Contra
phenytoin and phenobarb
grapefruits- increase levels
what should women do with deprkote?
increase folic acid 5mg daily
only drug used for local muscle spasms
dantrolene
pheno adverse
Can cause nystagmus and ataxia in excessive doses.
sedation
which drugs can decrease Vit K clotting factors?and with pregnant women?
Phenobarbital, phenytoin, carbamazepine and primidone
Pregnant women should have K supplement, 10 mg/daily and baby 1mg at birth
carbamazepine interactions
warfarin and Oral Contra
phenytoin and phenobarb
grapefruits- increase levels
what should women do with deprkote?
increase folic acid 5mg daily
only drug used for local muscle spasms not in CNS
dantrolene
abrupt withdrawl from baclofen can cause
hallucinations, seizure and paranoia
adverse of dantrolene
cns depression, hepatic toxic- women over 35, muscle weakness
how does dantrolene work?
suppresses release of Ca++
uses of dantrolene?
spasticity and malignant hyperthermia
generic of baclofen
lioresal