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16 Cards in this Set
- Front
- Back
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Cardiac cells are positive or negative in the interior compared to the external?
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Net neg. charge compared to the outside of the cell
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SA node and purkinje fibers have seperate A.Potentials, T/F?
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T
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Speed of A.P @
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SA Node=slow
-Atrium=fast -AV node=slow -His-purkinge=fast -Ventrical=fast |
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Vaughan Williams Classification is
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Used to classify antidysrhythmia drugs, how they effect Act. pot.
-Class 1 (A-c) -Class II-IV |
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Vaughan Williams Classification Mech of action: Class I
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Membrane stabilizing agent
fast Na channel blockers |
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Vaughan Williams Classification Mech of action and indication:
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-General class agent
-character of all three classes -Used for ventricular and life threatening dysrhythmias |
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Vaughan Williams Classification Mech of action: Class Ia
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quinidine, procainamide, disopyramide
-Na channel blocker -Delay repol. -inc. the APD -used for A-fib,PAC's, PVC's, V-Tach, Vent tach., and wolff-Parkinson-White syndrome |
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Vaughan Williams Classification Mech of action: Class Ib
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Block Na channel
-Accelerates repolarization -Decre. APD -Vent dysrhyth. only -PVC's, Vent tach, Vent Fib |
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Vaughan Williams Classification Mech of action: Ic
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Flecainide, Propafenone
-Block Na channel -little effect on APD or repol. -For severe Vent dysrhyth. -can be used for A-fib and flutter |
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Vaughan Williams Classification Mech of action: Class II
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Beta-blockers: atenolo,asmolol, petaprolo, propanolol: reduce or block sympathetic NS stim., decreased transmission of impulses to the heart
-Depress phase 4 depolorization -Gen myocardial depressents for SV and Vent dysrhyth. |
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Vaughan Williams Classification Mech of action: Class III
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-Amiodarone, bretylium, sotalol, ibutilide
-Incr. APD -Prolong repol in phase 3 -used for difficult to tx dysrhyth. |
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Vaughan Williams Classification Mech of action: Class Iv
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Verapamil, diltiazem
-Ca channel blockers -dpress phase 4 depol. -Reduce AV conduction -used for PSVT, rate control, A-fib and flutter |
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Digoxin and adenosine..
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no class, they have properties of several classes
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Adenosine..
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Slows AV node
-used to convert PSVT -short Half life, <10 secs. -IVP fast only -asystole for a few seconds |
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Antidysrhythmics side effects
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-dysrhythmia
-Hypersens. -Nausea -Vomit -Diarrhea -Dizz -Blurr vision -Headache |
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Nursing implications:
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-Drug & med Hx
-Vitals (BP, P , I&O, Card rhythem -serum K= pretherapy -assess contraidications and drug interactions -Monitor during therapy, rythem, HR, BP, general wellbeing, color, temp. H and B sounds -plasma drug levels -toxicity -take as directed, don't skip -contact if missed dose -no crush or chew -For Class I look at QT interval, >50% -IV pump -Lidocaine w/Epi not to be given w/ IV |
