Pharm 1.8 Clinical Uses Of Histamine And Serotonin And Ergot

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H1 first generation antagonist used as a sleep aid

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Tripelennamine

Front 2

H1 first generation antagonist used for motion sickness

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cyclizine

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H1 first generaition antagonist used for its sedative and antihistamine effects

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diphenhydramine

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H1 first generaition antagonist used for its antimuscarinic, sedative, and antiemetic effects

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promethazine

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H1 first generaition antagonist commonly used in cold medicines, but is less sedating

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chlorpheniramine

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H1 second generaition antagonist used as an antihistamine, and does not cause sedation

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Ioratidine

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H1 second generaition antagonist used as an antihistamine, and does not cause sedation

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Fexofenadine

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H1 second generaition antagonist used as an antihistamine in nasal sprays or eye drops

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azelastine

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Which H2 receptor antagonists that greatly inhibits the function of P450?

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cimetidine

Front 10

which H2 receptor antagonist slightly inhibits the action of P450 but also can lead to liver toxicity?

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Ranitidine

Front 11

Which H2 receptor antagonist leads to aynecomastia in men?

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Cimetidine

Front 12

Which H2 receptor antagonist blocks gastic acid secretion with the fewest side effects?

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Nizatidine

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Which H2 receptor antagonist blocks gastic acid secretion with moderate side effects but no effect on P450?

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Famotidine

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Which 5-HT receptor antagonist is used for skin allergies (antihistaminic) and diarrhea of carcinoid (antiserotinergic)?

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cyproheptadine

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Which 5-HT receptor antagonist is used in europe as an antihypertensive and antagonizes platelet aggregation?

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ketanserin

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which 5-HT receptor antagonist prevents N/V associated with chemotherapy?

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ondansetron

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Ergot derivative used for acute migranes

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ergotamine

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ergot alkaloid used in the treatment of chronic migranes

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methysergide

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ergot alkaloid used for postpartum hemorrhage

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ergonovine

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ergot derivative used for hyperplolactinemia

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bromocriptine