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39 Cards in this Set

  • Front
  • Back
What's Epi/NE's location/effect on: vascular smooth mm.
alpha1/beta2
What's Epi/NE's location/effect on: Renal vasculature
D1 (vasodilation)
What's Epi/NE's location/effect on: heart
beta-1
What's Epi/NE's location/effect on: pulmonary bronchioles
beta2
What's Epi/NE's location/effect on: pre-synaptic neurons
alpha2
What's Epi/NE's location/effect on: pupillary sphincter
alpha1 - mydriasis
What's Epi/NE's location/effect on: kidney JGA
Beta1 - renin release and decreased BP
What's Epi/NE's location/effect on: Beta cells of pancreas
alpha2 - inhibits insulin release
What's Epi/NE's location/effect on: alpha cells of pancreas
increased glucagon release
What's Epi/NE's location/effect on: liver
beta2 - glycogenolysis + gluconeogenesis
Treatment for: alcohol withdrawal
benzos
Treatment for: anorexia/bulimia
SSRIs
Treatment for: anxiety
Benzos, buspirone, SSRIs
Treatment for:ADHD
methylphenidate (ritalin)Amphetamines (dexedrine)dextroamphetamine (adderall)
Methylphenidate uses
ADHD, major depressive disorder, especially in elderly (as it has quick effect), narcolepsy, daytime sleepiness
Treatment for: Atypical depression
MAOI SSRIs Both better than TCAs
Treatment for: Bipolar disorder
Mood stabilizers: Lithium Valproic acid, Carbamazepine, Lamotrigine (these three anticonvulsants) Atypical antipsychotics: olanzapine, aripiprazole
Treatment for: Depression
SSRIs, NSRIs, TCAs
Treatment for: Depression with insomnia
Mirtazapine (tetracycline), Trazodone, Nefazodone (SNRI)
Treatment for: OCD
SSRIs, Clomipramine
Treatment for: Panic Disorder
SSRIs, TCAs, Benzos, beta-blockers, desensitization, CBT
Treatment for: PTSD
SSRIs, psychotherapy
Treatment for: Schizophrenia
Antipsychotics
Treatment for: Tourette's Syndrome
Antipsychotics (haloperidol)
Withdrawal symptoms: Post-use crash, including depression, lethargy, headache, stomach cramps, hunger, hypersomnolence [suicidality, fatigue, malaise, severe psychological craving]
Amphetamines, [cocaine]
Intoxication symptoms: Psychomotor agitation, impaired judgment, pupillary dilation, tachycardia, hypertension, hallucinations
amphetamines - inc. prolonged wakefulness and attention, cardiac arrhythmias, delusions, fever Cocaine - hallucinations includng tactile, paranoid ideations, angina, sudden cardiac death
Intoxication symptoms: restlessnes, insomnia, arrhythmias
caffeine - also: diuresis, muscle twitching Nicotine - anxiety
Withdrawal symptoms: Headache, weight gain
Caffeine - also lethargy, depression Nicotine - Irritability, anxiety, craving
Intoxication Symptoms: respiratory depression, low safety margin
Barbs - greater respiratory depression, lower safety margin Benzos - lesser respiratory depression, greater safety margin. Also: amnesia, ataxia, somnolence, additive effects with alcohol
Intoxification Treatment: Barbs and Benzos
Barbs - symptom management (assist respiration, increase BP) Benzos - Flumazenil (too much can induce withdrawal symptoms)
Withdrawal symptoms: Anxiety, seizures, life-threatening
Barbs - also delirium, cardiovascular collapse Benzos - rebound anxiety, tremor, insomnia
Intoxication Symptoms: Pinpoint pupils, constipation, seizures, CNS depression, nausea, vomiting
Opioids - OD is life-threatening b/c of seizures, no tolerance to constipation/pupillary constriction Tx: naloxone, naltrexone
Withdrawal Sx: piloerection, rhinorrhea, yawning. Also: insomnia, anorexia, sweating, dilated pupils, fever, nausea, stomach cramps, diarrhea (flu-like symptoms)
Opioids Tx: symptomatic, not life-threatening
Intoxication Sx: serum gamma-glutamyltransferase is sensitive indicator of use
Alcohol - also emotional lability, slurred speech, disinhibition, ataxia, coma, blackouts. AST&gt
Withdrawal Sx: Life-threatening, tachycardia, hypertension, malaise, nausea, seizures, delirium tremens (DTs), tremulousness, agitation, hallucination (inc. tactile, like crawling bugs)
Alcohol Tx: Benzos
Intoxication Sx: belligerence, impulsiveness, homicidality, psychomotor agitation, vertical and horizontal nystagmus, tachycardia, ataxia, psychosis, delirium
PCP
Withdrawal Sx: depression, anxiety, irritability, restlessness, anergia, disturbances of thought and sleep
PCP
Intoxication Sx: flashbacks, visual hallucinations, marked anxiety or depression, delusions, pupillary dilation
LSD - no other withdrawal Sx
Intoxication Sx - increased appetite, hallucinations, conjunctivitis, euphoria, anxiety, paranoid delusions
Marijuana - withdrawal - depression, irritability, insomnia, nausea, anorexia, most symptoms peak in 48 hours, last for 5-7 days, can be detected up to 1 month in urine.