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39 Cards in this Set
- Front
- Back
What's Epi/NE's location/effect on: vascular smooth mm.
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alpha1/beta2
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What's Epi/NE's location/effect on: Renal vasculature
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D1 (vasodilation)
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What's Epi/NE's location/effect on: heart
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beta-1
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What's Epi/NE's location/effect on: pulmonary bronchioles
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beta2
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What's Epi/NE's location/effect on: pre-synaptic neurons
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alpha2
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What's Epi/NE's location/effect on: pupillary sphincter
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alpha1 - mydriasis
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What's Epi/NE's location/effect on: kidney JGA
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Beta1 - renin release and decreased BP
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What's Epi/NE's location/effect on: Beta cells of pancreas
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alpha2 - inhibits insulin release
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What's Epi/NE's location/effect on: alpha cells of pancreas
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increased glucagon release
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What's Epi/NE's location/effect on: liver
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beta2 - glycogenolysis + gluconeogenesis
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Treatment for: alcohol withdrawal
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benzos
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Treatment for: anorexia/bulimia
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SSRIs
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Treatment for: anxiety
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Benzos, buspirone, SSRIs
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Treatment for:ADHD
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methylphenidate (ritalin)Amphetamines (dexedrine)dextroamphetamine (adderall)
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Methylphenidate uses
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ADHD, major depressive disorder, especially in elderly (as it has quick effect), narcolepsy, daytime sleepiness
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Treatment for: Atypical depression
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MAOI SSRIs Both better than TCAs
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Treatment for: Bipolar disorder
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Mood stabilizers: Lithium Valproic acid, Carbamazepine, Lamotrigine (these three anticonvulsants) Atypical antipsychotics: olanzapine, aripiprazole
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Treatment for: Depression
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SSRIs, NSRIs, TCAs
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Treatment for: Depression with insomnia
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Mirtazapine (tetracycline), Trazodone, Nefazodone (SNRI)
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Treatment for: OCD
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SSRIs, Clomipramine
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Treatment for: Panic Disorder
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SSRIs, TCAs, Benzos, beta-blockers, desensitization, CBT
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Treatment for: PTSD
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SSRIs, psychotherapy
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Treatment for: Schizophrenia
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Antipsychotics
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Treatment for: Tourette's Syndrome
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Antipsychotics (haloperidol)
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Withdrawal symptoms: Post-use crash, including depression, lethargy, headache, stomach cramps, hunger, hypersomnolence [suicidality, fatigue, malaise, severe psychological craving]
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Amphetamines, [cocaine]
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Intoxication symptoms: Psychomotor agitation, impaired judgment, pupillary dilation, tachycardia, hypertension, hallucinations
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amphetamines - inc. prolonged wakefulness and attention, cardiac arrhythmias, delusions, fever Cocaine - hallucinations includng tactile, paranoid ideations, angina, sudden cardiac death
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Intoxication symptoms: restlessnes, insomnia, arrhythmias
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caffeine - also: diuresis, muscle twitching Nicotine - anxiety
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Withdrawal symptoms: Headache, weight gain
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Caffeine - also lethargy, depression Nicotine - Irritability, anxiety, craving
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Intoxication Symptoms: respiratory depression, low safety margin
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Barbs - greater respiratory depression, lower safety margin Benzos - lesser respiratory depression, greater safety margin. Also: amnesia, ataxia, somnolence, additive effects with alcohol
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Intoxification Treatment: Barbs and Benzos
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Barbs - symptom management (assist respiration, increase BP) Benzos - Flumazenil (too much can induce withdrawal symptoms)
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Withdrawal symptoms: Anxiety, seizures, life-threatening
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Barbs - also delirium, cardiovascular collapse Benzos - rebound anxiety, tremor, insomnia
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Intoxication Symptoms: Pinpoint pupils, constipation, seizures, CNS depression, nausea, vomiting
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Opioids - OD is life-threatening b/c of seizures, no tolerance to constipation/pupillary constriction Tx: naloxone, naltrexone
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Withdrawal Sx: piloerection, rhinorrhea, yawning. Also: insomnia, anorexia, sweating, dilated pupils, fever, nausea, stomach cramps, diarrhea (flu-like symptoms)
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Opioids Tx: symptomatic, not life-threatening
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Intoxication Sx: serum gamma-glutamyltransferase is sensitive indicator of use
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Alcohol - also emotional lability, slurred speech, disinhibition, ataxia, coma, blackouts. AST>
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Withdrawal Sx: Life-threatening, tachycardia, hypertension, malaise, nausea, seizures, delirium tremens (DTs), tremulousness, agitation, hallucination (inc. tactile, like crawling bugs)
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Alcohol Tx: Benzos
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Intoxication Sx: belligerence, impulsiveness, homicidality, psychomotor agitation, vertical and horizontal nystagmus, tachycardia, ataxia, psychosis, delirium
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PCP
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Withdrawal Sx: depression, anxiety, irritability, restlessness, anergia, disturbances of thought and sleep
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PCP
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Intoxication Sx: flashbacks, visual hallucinations, marked anxiety or depression, delusions, pupillary dilation
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LSD - no other withdrawal Sx
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Intoxication Sx - increased appetite, hallucinations, conjunctivitis, euphoria, anxiety, paranoid delusions
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Marijuana - withdrawal - depression, irritability, insomnia, nausea, anorexia, most symptoms peak in 48 hours, last for 5-7 days, can be detected up to 1 month in urine.
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