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59 Cards in this Set
- Front
- Back
MOA of quinolones
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Inhibit DNA gyrase
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MOA of penicillin
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Block cell wall synthesis by inhibiting peptidoglycan cross-linkage
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Drug used for MRSA
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Vancomycin
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Vancomycin MOA
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Blocks peptidoglycan synthesis
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Type of resistance found with vancomycin
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Point mutation
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Meningitis prophylaxis in exposed patients
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Rifampin
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Technique used to diagnose perianal itching, and the drug used to treat it
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Scotch tape technique and mebendazole
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Two toxicities of aminoglycosides
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nephro and ototoxicity
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DOC for Legionnaires' disease
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Erythromycin
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MOA of sulfonamides
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Inhibit dihydropteroate synthase
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Penicillins active against penicillinase secreting bacteria
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Methicillin, nafcillin, and dicloxacillin
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Cheap wide spectrum antibiotic DOC of otitis media
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Amoxicillin
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Class of antibiotics that have 10% cross sensitivity with penicillins
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Cephalosporins
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PCN active against pseudomonas
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Carbenicillin, piperacillin and ticarcillin
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Antibiotic causing red-man syndrome, and prevention
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Vancomycin, infusion at a slow rate and antihistamines
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Drug causes teeth discoloration
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Tetracycline
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MOA of tetracycline
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Decreases protein synthesis by inhibiting 30S ribosome
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Drug that causes gray baby syndrome and aplastic anemia
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Chloramphenicol
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Drug notorious for causing pseudomembranous colitis
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Clindamycin
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DOC for tx of pseudomembranous colitis
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Metronidazole
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Treatment of resistant pseudomembranous colitis
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ORAL vancomycin
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Anemia caused by trimethoprim
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Megaloblastic anemia
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Reason fluoroquinolones are contraindicated in children and pregnancy
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Cartilage damage
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DOC for giardia, bacterial vaginosis, pseudomembranous colitis, and trichomonas
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Metronidazole
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Treatment for TB patients (think RIPE)
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Rifampin, Isoniazid, Pyrazinamide, and Ethambutol
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Metronidazole SE if given with alcohol
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Disulfiram-like reaction
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Common side effect of Rifampin
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Red urine discoloration
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MOA of nystatin
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Bind ergosterol in fungal cell membrane
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Neurotoxicity with isoniazid (INH) prevented by
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Administration of Vit. B6 (pyridoxine)
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Toxicity of amphotericin
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Nephrotoxicity
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SE seen only in men with administration of ketoconazole
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Gynecomastia
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Topical DOC in impetigo
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Topical mupirocin (Bactroban)
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DOC for influenza A
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Amantadine
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DOC for RSV
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Ribavirin
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DOC for CMV retinitis
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Ganciclovir
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SE for ganciclovir
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Neutro, leuko and thrombocytopenia
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Anti-viral agents associated with Stephen Johnson syndrome
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Nevirapine, amprenavir
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HIV antiviral class known to have severe drug interactions by causing inhibition of metabolism
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Protease inhibitors
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Antivirals that are teratogens
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Delavirdine, efavirenz, and ribavirin
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Antivirals associated with neutropenia
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Ganciclovir, zidovudine, saquinavir, and interferon
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HIV med used to reduce transmission during birth
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AZT (zidovudine)
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Drug used for African sleeping sickness
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Suramin
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Drug used in Chagas disease
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Nifurtimox
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Cephalosporins able to cross the BBB
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Cefuroxime (2nd generation) and Ceftazidime
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Cephalosporins that do NOT cross BBB
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Cefixime (3rd gen)
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Drug used for N. gonorrhea in females
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Ceftriaxone
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Cephalosporin causes kernicterus in neonates
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Ceftriaxone or cefuroxime
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SE of INH
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Peripheral neuritis and hepatitis
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Aminoglycoside that is least ototoxic
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Streptomycin
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Drug used in exoerythrocytic cycle of malaria
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Primaquine
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Oral antibiotic of choice for moderate inflammatory acne
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Minocycline
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Drug of choice for leprosy
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Dapsone
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DOC for herpes and its MOA
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Acyclovir; incorporated into viral DNA and chain termination
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Anti-microbials that cause hemolysis in G6PD-deficient patients
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Sulfonamides
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MOA of erythromycin
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Inhibition of protein synthesis at the 50s subunit of ribosome
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Anti-biotic frequently used for chronic UTI prophylaxis
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sulfamethoxazole/ trimethoprim
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Lactam that can be used in PCN allergic patients
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Aztreonam
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SE of imipenem
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Seizures
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Anti-viral with a dose limiting toxicity of pancreatitis
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Didanosine
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