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15 Cards in this Set
- Front
- Back
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What are the common Host factors affecting Antibiotic selection? |
1) Allergies 2) Age 3) Pregnancy 4) Metabolic Abnormalities 5) Organ Dysfunction 6) Concomittant Drugs 7) Concomittant Diseases |
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Which antibiotics are contraindicated in pregnancy? |
Quinolones, Sulfa drugs, Trimethoprim, Aminoglycosides and Tetracyclines |
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How does Time dependent Killing affect antibiotic dosing?
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Dosing should aim to maximize time that drug concentration is above MIC |
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How does Concentration dependent Killing affect antibiotic dosing?
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Dosing should aim to achieve high peak serum drug concentrations relative to MIC of the pathogen |
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How does Concentration dependent with Time dependence affect antibioitc dosing?
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Dosing should aim to maximize the amount of drug relative to MIC
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Which antibiotics are examples of Time dependent killing?
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Penicillin, Cephalosporins, Carbapenem |
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Which antibiotics are examples of Cocentration dependent killing? |
Aminoglycosides, Fluroquinolones, Daptomycin, Metronidazole, Amphotercin B, Fungins
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Which antibiotics are examples of Concentration dependent with time dependence?
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Fluroquinolones, Macrolides, Clindamycin, Tetracyclines, Linezolid, Vancomycin and Azoles |
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"Every attempt should be made to obtain specimens for culture and sensitivity testing prior to initiating antibiotics" True or False
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True
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"Patients who have delayed derm reactions to penicillins can receive Cephalosporins" True or False?
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TRUE
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"Patients with Type 1 hypersensitivity to penicillins should receive Cephalosporins" True or False
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False, they cannot receive Cephalosporins |
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"Patients with Type 1 hypersensitivity to penicillins should not receive Carbapenems" True or False
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TRUE
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"Estimated renal function does not need to be calculated for every patient who is to receive antibiotics" True or False? |
FALSE |
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"All concomitant drugs and nutritional supplements should be reviewed when an antibiotic is added to a patients therapy" True or False
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TRUE |
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Assuming you know they will be effective, which is preferable: Narrow Spectrum Antibiotics or Broad Spectrum Antibiotics?
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Narrow Spectrum
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