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11 Cards in this Set
- Front
- Back
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What are the effects of smoking cessation for 2-3 weeks?
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Normal mucocilliary function
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What are the effects of pregnancy on PFTs?
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Lung volumes/capacities not effected, but FRC decreased 15-20%
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What effect does obesity have on PFTs?
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Restrictive pattern; Decreased ERV, VC, FRC, PaO2, Pulmonary compliance; Increased CO2 production/O2 consumption d/t increased biomass
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What is the effect of a general anesthetic on FRC?
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Decreases it by 15-20%
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How is obstructive disease dx'd w/ PFTs?
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Pre and post-albuterol measurements are taken, if a 12-15% or > change in measurements, suggests true obstructive disease.
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What is a normal HCO3-?
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22-27
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What is atmospheric N2 pressure?
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591 mmHg
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What is SaO2 at a PaO2 of 100 on a normal O2-dissociation curve?
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97%
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What is SaO2 at a PaO2 of 40 on a normal O2-dissociation curve?
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75%
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Describe renal control of acid/base balance
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In the proximal tubule (90%), H2O+CO2 -> H2CO3 -> H+ + HCO3-. H+ is traded for Na+ by a basolateral exchanger, and Na+ and HCO3- are pushed back into the blood
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Describe the role of NH3 secretion in acid/base balance
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Secreted NH3 + H+ -> NH4+, which cannot diffuse back accross the membrane, and thus serves as a H+ sink.
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