Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
25 Cards in this Set
- Front
- Back
|
RBC cholinesterase is better or worse measure of synaptic inhibition?
|
Better
|
|
|
RBC cholinesterase regenerates more _____ than plasma cholinesterase
|
Slowly
|
|
|
Plasma cholinesterase falls _____ RBC cholinesterase?
|
Before
|
|
|
Type I pyrethroids
|
T syndrome (tremor)
Non-CN |
|
|
Type II pyrethroids
|
CS syndrome
alpha CN |
|
|
Lindane
|
GABA antagonist
|
|
|
DDT
|
Na Channel blockade
Neuroexcitation |
|
|
Amitraz
|
alpha 2 agonism
|
|
|
Fipronil
|
GABA antagonist
|
|
|
Imidacloprid
|
Nicotinic
|
|
|
Low toxicity rodenticides
|
Anticoagulants
Norbormide Bromethalin |
|
|
Hight toxicity rodenticides
|
SMFA/Fluoroacetamide
VACOR (PNU) Phosphine Strychnine |
|
|
VACOR (PNU)
|
Interferes with nicotinamide
Causes: Diabetes Orthostasis CNS tox GI perforation |
|
|
VACOR TREATMENT
|
GIVE
NIACIN and NICOTINAMIDE |
|
|
Phosphine
|
Inhibits ETC
Rotten fish/ garlic odor |
|
|
Phoshpine symptoms
|
Delayed ALI
Multisystem failure |
|
|
Strychnine
|
from nux vomica
glycine inhibition |
|
|
ATNU
|
Acute Lung Injury
Mechanism unknown |
|
|
Anticoagulants inhibit
|
Vit K epoxide reductase
Vit K quinone (reductase?) |
|
|
Bromethalin
|
Uncouples ox/phos
AMS, seizures, coma |
|
|
Norbormide
|
Norway rat selective smooth muscle constriction
|
|
|
Paraquat/Diquat
|
Depletion of NADPH, oxygen reoxidizes them and they deplete more NADPH
|
|
|
Chlorphenoxy compounds
|
Example is 2,4,5 triphenoxyacetic acid
Uncontrolled lethal growht |
|
|
Methyl bromide
|
Chlorpicrin additive
Skin: blistering Pulm: ALI, dyspnea CNS visual disturbance, seizure, coma |
|
|
Sulfuryl fluoride
|
HEaver than air
Chloropicrin Fluoride poisoning mechanism? |
