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27 Cards in this Set

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A drug that affects both divisions of the autonomic system is going to bind to, or block, which type of neurotransmitter?

Nicotinic

A drug is called an agonist if it __________.

Acts like the endogenous neurotransmitter by binding to its receptor

Which type of drug would be an antidote to atropine poisoning?

Muscarinic agonist ie. Pilocarpine

Which kind of drug would have anti-anxiety effects?

muscarinic agonist

Which type of drug could be used to treat asthma by opening airways wider?

Sympathomimetic drug

Mimics affects of sympathetic nervous system stimulation.

Agonist

Any exogenous substance that binds to a receptor and produces a similar effect to the endogenous ligand.

Antagonist

Any exogenous substance that binds to a receptor and produces an opposing effect to the endogenous ligand.

Anticholinergic Drugs

Drugs that interrupt or reduce the function of the parasympathetic nervous system.

Endogenous Chemical

Substance produced and released within the body to interact with a receptor protein.

Exogenous Chemical

Substance from a source outside the body, whether it be another organism such as a plant or from the synthetic processes of a laboratory, that binds to a molecular drug target

Mydriasis

Dilation of the pupil

Parasympathomimetic drugs

Drugs that enhance and/or mimic the function of the parasympathetic nervous system

Sympatholytic drug

Drug that interrupts, or ‘lyses’ the function of the sympathetic nervous system

Sympathomimetic drug

Drug that enhances or mimics the function of the sympathetic nervous system.

Which drug can be used as an antidote for cholinesterase poisoning or poisoning by mushrooms containing muscadine?

Atropine

The main hormones of the adrenal medulla include:

Dopamine, Adrenaline & Noradrenaline

Fight or Flight response

Cholinergic

Pertaining to, activated by, or having the same function as acetylcholine.

Post synaptic neuron

The nerve cell the bears receptors for neurotransmitters release into the synaptic cleft by the presynaptic neuron

Ganglion

A cluster of interconnecting nerve cells outside the brain

Parasympathetic

Relating to the part of the autonomic nervous system that inhibits or opposes the effects

Cholinergic Crisis

Over stimulation at neuromuscular junction due to an excess of acetylcholine (AChE) as a result of the inactivity of AChE enzyme (acetylecholinesterase), which usually breaks down acetylcholine

Efferent

Neurons that send impulses from the central nervous system to limbs and organs.


ie. controls motor function

Efferent

Neurons that send impulses from the central nervous system to limbs and organs.


ie. controls motor function

Afferent

Neurons that receive information from our sensory organs (ie. skin, eyes) and transmit this input to central nervous system

Activation of the Sympathetic nervous system results in:

Fight/Flight response, pupil dilation, inhibition of digestion, increased hepatic glucose output, release of adrenaline/noradrenaline, contraction of rectum, release of bladder, bronchodilation, increased HR + BP

Activation of the Sympathetic nervous system results in:

Fight/Flight response, pupil dilation, inhibition of digestion, increased hepatic glucose output, release of adrenaline/noradrenaline, contraction of rectum, release of bladder, bronchodilation, increased HR + BP

Activation of the parasympathetic nervous system results in:

Rest and Digest, pupil constriction, stimulation of salivary glands, bronchial construction, decrease is HR + BP, stimulation of digestion