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9 Cards in this Set
- Front
- Back
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What are 4 classes of peripheral nerve diseases?
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1.) inflammatory neuropathies
2.) infectious neuropathies 3.) hereditary neuropathies 4.) acquired metabolic/toxic neuropathies |
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What type of neuropathy is guillan-barre syndrome?
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Inflammatory neuropathy
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What causes Guillan-Barre? What do these people experience?
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Life threatening disease of CNS with flu like illness and ascending paralysis. It is immune mediated demyelination that usually resolves with time. Widely distributed throughout the PNS. Rapid onset of weakness, loss of deep tendon reflexes, and some loss of sensation
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What type of neuropathy is Leprosy (Hansen disease)?
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It is an infectious neuropathy with slowly progressive infection of skin and nerves that's caused by mycobacterium leprae that's transmitted thru respiratory droplets and can cause disabling deformities. Lepromatous leprosy is the most severed and the patient's immune system does not respond. Tuberculoid leprosy is less severe and localized and body forms granulomas to fight bacteria
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What type of neuropathy is Varicella Zoster?
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Inflammatory neuropathy. Common viral infection of the PNS. Reactivation is painful, vesicular, dermatomal rash. histology shows neuronal destruction and multinucleated giant cells.
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What type of neuropathy is neuropathy type 1/Charcot Marie Tooth Disease?
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Hereditary neuropathy
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What happens with Charcot-Marie Tooth disease?
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Repetitive demyelination and remyelination and results in muscle loss where this is a loss of sensation but pain is intact
Symptoms start in childhood or early adulthood and people have high arches, hammer toes, and muscle atrophy patients have norma life spans One of the first symptoms is foot drop |
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What happens in peripheral neuropathy with diabetes?
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Very common and seen with symmetric sensory and motor neuropathy in distal nerves, such as feet. Occurs in stocking-glove distribution
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How can malignancies cause neuropathy?
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They are common cause of mononeuropathy with neoplasm pushing on nerve plexus
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