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30 Cards in this Set
- Front
- Back
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1st generation antihistamine that produces sedation as a side effect and potentiates analgesia
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promethazine
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Fentanyl transmucosal system perioperative indications
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-preanesthetic used in children/adults
-conscious sedation prior to diagnostic or therapeutic procedures |
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boxed warning for Fentanyl transmucosal system
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-risk of hypoventilation
-use only as premedication or for conscious sedation in hospital setting |
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Fentanyl transmucosal system contraindicated for _________
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treatment of acute and chronic pain
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disadvantages of routine practice of "IM opioids as needed" for postoperative analgesia
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- 75% pts may still experience moderate to severe pain
- delay between pt request and dosing |
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advantage of patient-controlled analgesia
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-avoids peak and trough opioid concentrations between injections
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two types of patient-controlled analgesia
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1. continous infusion (basal delivery)
2. intermittent self-boluses (provision for "rescue" dose and breakthrough pain) |
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Fentanyl transdermal Sx indications post-op
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-indicated for short-term management of acute post-op pain in adults requiring opioid analgesia during hospitalization
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advantages of epidural opioid analgesia over parenteral therapy
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-superior pain relief
-less sedation and respiratory depression -continuous epidural infusion avoids peak and trough opioid concentrations |
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what two types of drugs can be administered epidurally for perioperative analgesia?
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1. opioids
2. local anesthetics |
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is the routine prophylaxis of postoperative N/V recommended?
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NO
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antiemetic agents that affect serotonergic receptors (2)
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1. ondansetron (Zofran)
2. granisetron |
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antiemetic agent that affects histaminic receptors (1)
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promethazine (phenergan)
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antiemetic agents that affect dopaminergic receptors (2)
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1. droperidol
2. metoclopramide (Reglan) |
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antiemetic agent that affects cholinergic receptors (1)
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scopalamine
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antiemetic agent that affects substanceP/neurokinin receptors
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aprepitant
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indication for aprepitant
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-prevention of N/V in emetogenic CA chemotherapy (acute and delayed syndromes)
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indication for ondansetron (Zofran)
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-prevention of post-op N/V
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indication for granisetron
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-prevention and tx of postoperative N/V
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indication for droperidol
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-prevention and tx of N/V
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boxed warning for droperidol
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-QT prolongation and production of torsades
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__________ has an unlabeled use for postoperative N/V
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metoclopramide (Reglan)
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promethazine can be used for prophylaxis and treatment of ?
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postop N/V
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scopolamine indicated for ?
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prevention of N/V associated with recovery from anesthesia and surgery
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anticholinergics are AKA ________
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antisialagogues
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which anticholinergic agent is the most potent antisialagogue and has the most significant sedation?
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scopolamine
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what is a potent antisialagogue for gastric, bronchial, and salivary secretions?
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glycopyrrolate
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what is a prokinetic agent used for prophylaxis of aspiration pneumonitis
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metoclopramide (Reglan)
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what is the MOA metoclopramide (Reglan) in the prophylaxis of aspiration pneumonia?
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-prokinetic agent (gastric motility stimulant)
-reduces gastric volume in predisposed pts by promoting gastric emptying |
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how are H2-receptor antagonists dosed in the prophylaxis of aspiration pneumonia?
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-give dose in the evening prior to surgery
-give another dose prior to surgery |
