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30 Cards in this Set

  • Front
  • Back
1st generation antihistamine that produces sedation as a side effect and potentiates analgesia
promethazine
Fentanyl transmucosal system perioperative indications
-preanesthetic used in children/adults
-conscious sedation prior to diagnostic or therapeutic procedures
boxed warning for Fentanyl transmucosal system
-risk of hypoventilation
-use only as premedication or for conscious sedation in hospital setting
Fentanyl transmucosal system contraindicated for _________
treatment of acute and chronic pain
disadvantages of routine practice of "IM opioids as needed" for postoperative analgesia
- 75% pts may still experience moderate to severe pain
- delay between pt request and dosing
advantage of patient-controlled analgesia
-avoids peak and trough opioid concentrations between injections
two types of patient-controlled analgesia
1. continous infusion (basal delivery)
2. intermittent self-boluses (provision for "rescue" dose and breakthrough pain)
Fentanyl transdermal Sx indications post-op
-indicated for short-term management of acute post-op pain in adults requiring opioid analgesia during hospitalization
advantages of epidural opioid analgesia over parenteral therapy
-superior pain relief
-less sedation and respiratory depression
-continuous epidural infusion avoids peak and trough opioid concentrations
what two types of drugs can be administered epidurally for perioperative analgesia?
1. opioids
2. local anesthetics
is the routine prophylaxis of postoperative N/V recommended?
NO
antiemetic agents that affect serotonergic receptors (2)
1. ondansetron (Zofran)
2. granisetron
antiemetic agent that affects histaminic receptors (1)
promethazine (phenergan)
antiemetic agents that affect dopaminergic receptors (2)
1. droperidol
2. metoclopramide (Reglan)
antiemetic agent that affects cholinergic receptors (1)
scopalamine
antiemetic agent that affects substanceP/neurokinin receptors
aprepitant
indication for aprepitant
-prevention of N/V in emetogenic CA chemotherapy (acute and delayed syndromes)
indication for ondansetron (Zofran)
-prevention of post-op N/V
indication for granisetron
-prevention and tx of postoperative N/V
indication for droperidol
-prevention and tx of N/V
boxed warning for droperidol
-QT prolongation and production of torsades
__________ has an unlabeled use for postoperative N/V
metoclopramide (Reglan)
promethazine can be used for prophylaxis and treatment of ?
postop N/V
scopolamine indicated for ?
prevention of N/V associated with recovery from anesthesia and surgery
anticholinergics are AKA ________
antisialagogues
which anticholinergic agent is the most potent antisialagogue and has the most significant sedation?
scopolamine
what is a potent antisialagogue for gastric, bronchial, and salivary secretions?
glycopyrrolate
what is a prokinetic agent used for prophylaxis of aspiration pneumonitis
metoclopramide (Reglan)
what is the MOA metoclopramide (Reglan) in the prophylaxis of aspiration pneumonia?
-prokinetic agent (gastric motility stimulant)
-reduces gastric volume in predisposed pts by promoting gastric emptying
how are H2-receptor antagonists dosed in the prophylaxis of aspiration pneumonia?
-give dose in the evening prior to surgery
-give another dose prior to surgery