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23 Cards in this Set

  • Front
  • Back
Risks for perinatal stroke
History of infertility
Vacuum extraction
Primiparity (first child)
Emergency c-section
Chorioamnionitis (placental infection)
Preeclampsia (hypertension plus kidney problems)
Infection during pregnancy
Twin gestation
Advanced maternal age
Common regions for perinatal stroke
left MCA - in term infants (identified by seizure or hemiplegia emering at 1 mont)
periventricular hemorrhage infarctions - in preterm infants (identified via routine ultrasound)
Fetal/neonatal risk factors for stroke
Fetal heart rat abnormalities during birth
Asphyxia
Low apgar scores
Resuscitation at birth
Cardiac anomalies
Polycythemia (excess red cells)
Infection
Coagulation abnormalities
Smallness for gestational age
Percent of term perinatal strokes that present with seizures
75%
Percent of perterm perinatal strokes that are discovered incidentally
70%
Percent of perinatal strokes with cerebral palsy
40-60%
Percent of perinatal strokes with epilepsy
40%
Percent of perinatal strokes with behavioral problems
20%
Percent of perinatal strokes who present as neurologically normal
30-50%
Risk factors for poor outcome in perinatal stroke
abnormal exam at discharge from nursery, neonatal seizures, abnormal EEG, blood clotting abnormalities, and late presentation of CP
Hemiplegic gait
CIRCUMDUCTING; that is the body position is crouched and the impaired legs lifts and swigs
MRI findings in perinatal stroke
Thinning of corpus callosum (could result in abnormalities for uninjured side as well)
Low white matter in lobar region contralateral to injury site
IQ changes over time in perinatal stroke
Tthe gap between IQ levels of children with PS and TD may be expected to widen over time as complexity demands increase
Language in perinatal stroke
Delays
Early RH injury resulted in greatest deficits in comprehension
Left posterior temporal damage was associated with deficits in word and grammatical production
However, show normal developmental course of language development
By middle school PS children perform in the low normal age
The "where" visual system in perinatal stroke
Occipital-parietal cortex
Left - dominant for categorical spatial relations
Right - dominant for coordinate spatial relations (precise metric information about location)
Deficits seen in PS children but with remarkable plasticity with normalization by the age of 5
Face processing in perinatal stroke
Affected by early LH or RH injury - face processing is established early and may not be so plastic, especially for children with RH lesions
Reorganization of the motor system after perinatal stroke
If small lesion, see intact crossing of corticospinal from injured hemisphere to paretic limb
(Sensory functions do not show same reorganization)
If large lesion, rely on that small portion of corticospinal track that does not cross
If intermediate lesion, see both
White matter abnormalities after perinatal stroke
Reduced corpus callosum size (related to sections that would have connected affect side to other hemisphere)
Reduced white matter volume in uninjured side
Language development after perinatal stroke
Order of emergence of skills is the same
Delays at each new level of linguistic challenge, regardless of which hemisphere is involved, later mastery and movement on to next challenge
Language lateralization after perinatal stroke
In RH stroke, left hemisphere remains dominant for language
In LH stroke, bilateral representations emerge; if the LH remains involved, rather than more RH involvement, the better the language functioning
Visual pattern processing after perinatal stroke
Visual pattern processing in RH stroke: Retention of local detail processing subserved by LH “what” network, not global processing
Visual pattern processing in LH stroke: Retention of global characteristics subserved by RH “what” network, with paucity of details (for example on Rey)
Lateralization of visual spatial processing after perinatal stroke
unlike language, it becomes lateralized to non-injured side
Effects of perinatal stroke on emotion expression
RH injury show increased negative affect and fewer/less fluent positive affect, as compared to LH stroke and controls