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8 Cards in this Set
- Front
- Back
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Toxoplasmosis
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When: 1st-3rd TM (most severe in 1st)
Sx: Cerebral Ca++ Hydrocephalus and/or Microcephaly Chorioretinitis myocarditis hepatosplenomegaly jaundice vomiting IUGR maculopapular rash Labs: thrombocytopenia IgM - ELISA IgG for life isolate organism, culture Tx: pyrimethamine & sulfadiazine, leucovorin Later life: 70-90% aymp at birth effects may not manifest until 2nd-3rd decade up to 80% have learning and visual problems later |
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Rubella
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When: 1st TM
Sx: Cerebral Ca++ Hydrocephalus and/or Microcephaly Deafness Microphthalmia Cataracts PDA IUGR cyanotic w/petechial rash (blueberry muffin) Labs: thrombocytopenia IgM HI titer viral culture |
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CMV
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When: ALL
Sx: Cerebral Ca++ Microcephaly Convulsions Meningoencephalitis Deafness (often progressive) Chorioretinitis Hepatosplenomegaly jaundice IUGR Labs: PCR for CMV DNA viral culture 90% asymp) |
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HSV
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When: ALL, into PP
Sx: Hydranencephaly Microcephaly Chorioretinitis Microphthalmia cerebral Ca++ encephalitis pneumonia hepatosplenomegaly Cutaneous vesicles " scars Labs: PCR for HSV DNA viral culture MAY APPEAR SEPTIC |
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Varicella
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When: 1st TM & intrapartum
Sx: Microcephaly Chorioretinitis cataracts convulsions Microphthalmia myocarditis Horner's Cerebral Ca++ pneumonitis visceral lesions Cutaneous vesicles " scars unilat limb hypoplasia Labs: VZV Ab viral culture |
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Syphilis - Early (<2 y/o)
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MAJOR
MC Sx = periostitis Other Sx' snuffles, rash, condyloma lata, osteochondritis/myelitis, pneumonia alba (obliterative lung fibrosis) MINOR perioral fissures, mucous patches, hepatosplenomegaly, lymphadenopathy, hematolgic signs, hydrops, pseudoparalysis of Parrot, SNC problems |
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MC Sx Syphilis <2 y/o
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periostitis
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Syphilis -Late (>2 y/o)
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Hutchinson's TrIaD: teeth (peg-shaped upper central incisors), interstitial keratitis, deafness
frontal bossing, short maxillae, protruding mandible, saddle nose, Clutton's joints (bilat knee effusion), saber shins, sternoclavicular thickening, flaring scapulas |
