Pep Sample Test Cards

Front 1

The action of acetylcholine is terminated primarily by

Back 1

Acetylcholinesterase

Front 2

Atropine would be classified as

Back 2

Direct acting cholinergic antagonist

Front 3

The rate limiting step in the synthesis of dopamine

Back 3

Tyrosine

Front 4

High tissue binding would be associated with a

Back 4

High volume of distribution

Front 5

The fraction or percentage of the administered dose of a drug reaching the systemic circulation is referred to:

Back 5

Bioavailability

Front 6

Parkinsonism is a degenerative disorder of

Back 6

Basal ganglia

Front 7

Which of the following is the most critical index of nervous system dysfunction:

Back 7

Pattern of breathing

Front 8

Synthesis and breakdown of all body substances is referred to as:

Back 8

Catabolism

Front 9

Creatine is constantly released from _________ and is excreted primarily by glomerular filtration.

Back 9

Skeletal muscle

Front 10

Autoreceptors normally

Back 10

open ion channels on the postsynaptic membrane

Front 11

Respiration

Back 11

heart rate

Front 12

Severe damage to the amygdala and hippocampus would result in

Back 12

Inability to form new memories.

Front 13

A shift in the dose response curve to the left would be indicative of

Back 13

Increased sensitivity

Front 14

Which form of a drug would most readily cross biological membranes:

Back 14

Unionized

Front 15

The most severe and potentially life threatening withdrawal syndrome is associated with

Back 15

Alcohol

Front 16

The type of drug reaction caused by penicillin is

Back 16

Autoimmune syndrome

Front 17

Following a large overdose of nortriptyline

Back 17

which of the following would b lease likely to be observed:

Front 18

Which of the following type of cells is part of the blood brain barrier

Back 18

Astrocyte

Front 19

Parkinson and Huntington diseases are associated with defects in which areas:

Back 19

Basal ganglia

Front 20

Body temperature is primarily regulated by

Back 20

Hypothalamus

Front 21

Enzyme-inducing anticonvulsant drugs (e.g. phenobarbital) would interact with which of the following to inhibit their actions

Back 21

Aspirin

Front 22

Neuroleptic malignant syndrome would be a symptom which is associated with:

Back 22

Antipsychotic

Front 23

Renal dysfunction would be detected by the following

Back 23

Elevated BUN

Front 24

The neurotransmitter released at the majority of sympathetic postganglionic synaptic is

Back 24

Norepinephrine

Front 25

Mania is associated with an increase in which neurotransmitter

Back 25

acetylcholine

Front 26

Initial treatment of alcoholism

Back 26

Long acting benzodiazepine

Front 27

“Water toxicity” has been reported with the abuse of

Back 27

Ecstasy

Front 28

Hepatic dysfunction would have which effect on a prodrug

Back 28

Decreased effect

Front 29

Constipation

Back 29

respiratory depression

Front 30

Addiction and abuse would be the most likely in which class of drugs

Back 30

Schedule I

Front 31

Baroreceptors are associated with

Back 31

Blood pressure control

Front 32

carbamazapine

Back 32

considered a mood stabilizer but also has the ability to induce liver enzymes

Front 33

Which of the following is released from mast cells

Back 33

Epinephrine

Front 34

First dose effect is associated with

Back 34

increased response

Front 35

methadone

Back 35

prevents withdrawal without producing euphoria

Front 36

Beta blockers are sometimes prescribe for the treatment of anxiety but should be used cautiously or not at all in patients with

Back 36

Asthma

Front 37

Serotonergic neurons originate predominately in what area of the brain stem

Back 37

raphe nuclei

Front 38

The most common limiting adverse effect of L-dopa

Back 38

dyskinesia

Front 39

Dose adjustments must be continually made for which of the following

Back 39

carbamazepine

Front 40

The tachycardia associated with the use of tricyclic antidepressants is due to blockade of which receptor

Back 40

muscarinic

Front 41

In adjusting a drug dosage in a patient with renal disease

Back 41

which of the following would be the best index to use

Front 42

Chronic use of which of the following should involve routine e blood glucose monitoring:

Back 42

atypical antidepressants

Front 43

Chronic renal disease would be the greatest concern

Back 43

lithium

Front 44

approved for the treatment of post traumatic syndrome disorder

Back 44

zoloft