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161 Cards in this Set

  • Front
  • Back
What is an occult fever?
a fever with no other localized findings on hx and PE
What is the MCC of an occult fever?
UTI
What bugs affects thos less than 3 months?
-E.coli
-Klebsiella
-enterococcus
-Grp B step
-listeria
What bug affect those 3-36 months?
encapsulated bacteria
-strep peumoniae
-Neisseria
-Hib
What bug tends to affect older children most often?
GABHS
In older kids, bacteremia is infrequent and most often caused by what?
Neisseria
What are some signs of a serious illness in a child?
-irritablity
-pooor eye contact
-failure to recognize parents
-porr interaction
What cqan be seen on PE for a very ill child?
-fever
-hypothermia
-tachypnea
-irregular respirations
-apnea
-tach or bradycardia
-hypotension
-cyanosis
-poor perfusion
-petechial or purpuric rash
What is the most common disase dx in children?
AOM
MCC of AOM is what?
strep pnemo
Name 5 risk factors for development of AOM
-6-18 months old
-bottle fed, pacifier use
-born in fall
-Native American
-lower socioeconamic class
Tympanocentesis should only be used in what pts?
immunocompromised pts with AOM
What is DOC for AOM?
-amoxicillin
What is the MCC of bacterial pharyngitis?
GABHS
Pharyngitis in 2-5 y/o is most often the result of what?
infection with respiratory viruses
What is the viral syndrome of viral pharyngitis?
-fever
-rhinorrhea
-cough
-mild pharyngitis
-fatigue
-anorexia
-ab pain
GABHS pharyngitis is manifested by what symptoms?
-acute fever
-headache
-sore throat
-ab pain
-NO cough or rhinorrhea
HSV-1 pharyngitis is characterized by what?
anterior protion of the mouth and lips are red
What is a finding of pharyngitis caused by EBV?
large tonsils (posterior adenopathy)
What often precedes a peritonsuillar abscess?
pharyngitis
A peritonsillar abscess is rarely _______/
bilateral
What is seen on PE for a peritonsillar abscess?
-high fever
-difficulty swallowing
-change in speech
-uvula is displaced
What bugs usually cause a peritonsillar abscess?

Tx?
-GABHS
-S. aureus
-aerobic and anerobic baceria

-tx with IV abx and sx drainage
Tell me about findings in a child with retropharyngeal abscesses.
-appear ill with high fever, difficulty swallowing, dyspnea
-swelling of posterior larynx
-lateral neck films reveal swelling
Acute epiglotitis is rare b/c of what?
Hib vaccine
What is the PE findings in acute epiglotitis?
-swollen, cherry red epiglottis with laryngoscopy
What is the tx for acute epiglottis?
-intubation and observation in an ICU and IV abx until swelling resolves
What does PFAPA stand for?
-periodic fever, aphthous stomatitis, pharyngitis, cervical adenitis
What are some PE finding in PFAPA?
-periodic high fever occuring q 3-4 weeks
-tonsils are moderately enlarged, erythemic, w/o exudate
-cervical adenopathy
-unknown etiology
What is the MCC viral agent associated with the cold?
rhinovirus
What are some airborne infections that cause URIs?
-rubeola
-varicella
-TB
What are some droplet transmission infections that cause URIs?
-adenovirus
-coronavirus
-influenza
What are some contact transmission infections that cause URIs?
-RSV
-parainfluenza
-enterovirus
-rhinovirus
What is bronchiolitis?
obstructive pulmonary disease of infants and young children
MCC of bronchiolitis?
RSV
RSV is most common in what children?
those younger than 1 with a peak incidence at 2-6 months
What are 2 other causes of bronchiolitis other than RSV?
-parainfluenza virus
-adenovirus
In bronchiolitis, viral proliferation causes what?
edema, necrosis of epithelium lining of the airway, sloughing of ciliated cells, and formation of mucous plugs
What is RSV season?
Nov-April
What are some risk factors for the development of RSV?
-premies
-congenital heart disease
-CF
-immunodeficient
Chilren with RSV present how?
-lethargy
-irritable
-apnea
-low grade fever
-tachypnea
-tachycardia
-dehydration
-dry or cyanotic mucous membranes
What is the medical tx for RSV or Bronchiolitis?
-admit ill looking children
-O2 and bronchiodilators
-Ribivarin
-steriod DO NOT help
Croup mainly affects who?
boys in first 3 years of life in late fall or early winter
What is the MCC of croup?
parainfluenza
What are some PE findings in croup?
-rhinorrhea
-hoarseness
-barky cough
-restlessness and agitation (hypoxia)
-fever
-tachypnea
-tachycardia
What is the tx for croup?
-supportive
-cool, humidified air
-nebulized racemic epi
-steroid decrease severity, duration and hospitilzation length
What kids have greatest attack rates of influenza?
school aged children
Influenza A is found where?
in lots of animals
Influenza B is found where?
humans
What is Antigenic shift?
abrupt change with influenza A. Disappears and comes back different
What is antigenic drift?
-occurs in both flu A and B and is what causes seasonal epidemics
What is seen in hx of flu in older children and adults?
-fever
-HA
-myalgia
-sore throat
-nonproductive cough
What symptoms are seen in chilren with the flu?
GI symptoms
What drugs can be used to tx flu A?

B?
-Amantadien or Rimantadine

-Zanamivir or Oseltamivir
What are the prodromal sx of viral pneumonia?
-rhinorrhea
-cough
-low grade fever
-pharyngitis
What is seen in the hx bacterial pneumonia?
-more abrupt onset than viral
-fever
-cough
-CP
-shaking chills
-initially non-productive cough
-neck pain and stiffness
What is seen on PE for viral pneumonia?
-irritable, nasal flaring, subcostal intercostal refractions, cyanotic membranes
-fever less than 102.2
-tachypnea
-tachycardia
-rales
-wheezes
-mild hepatosplenomegaly
What is seen on PE for bacterial pneumonia?
-ill looking or anxiousness
-high fever, tachycardia, tachypnea, hypotension
-nasal flaring and cyanosis
-fever, HA, and cough
-rash on occasion
-tactile fremitus
-dullness to percussion
-bronchophony
-egophony
-bronchial breath sounds
-rales
In babies less than 2-3 months, what bugs cause pneumonia?
-S. agalactiae
-gram negatives
-Listeria
-s. aureus
What is reactive adenopathy?
-diffuse mild inflammation of lymph nodes that occurs in response to systemic or local infection
In reactive adenopathy, how do nodes feel?
-rubbery, mobile with a diamter less than 2cm
What is lymphadenopathy?
infection of the nodes itself
What are the MCCs of lymphadenopathy?
GABHS or S. aureus
What is found on PE for lymphademopathy?
-poorly mobile, soft tissue edema, erythema greater than 2cm
-tonsillar and anterior cervical nodes are mainly involved
Tell me about the findings of atypical mycobaceria lymphadenopathy in those less than 4.
-submandibular, perauricular, anterior cervical, inguinal, or epitrochlear nodes
-bilateral adenitis isn't present
-no fever or other sx
-mildly tender, little warmth or inflammation
-after several weeks, nodes become fixed and discolorded
Moratility in bacterial meningitis is highest with what bug in children?
S. pneumoniae
What types of bugs infect infants and older infants and cause meningitis?
-enteric pathogens in infants and encapsulated bacteria in older infants and children
What is seen in the hx of of an infant and young child with bacterial meningitis?
-irritable
-anorexia
-vomiting
-inconsolable crying
-lethargy
-seizures
-focal neurological signs
What is seen in the hx of an older child with bacterial meningitis?
-HA
-back pain
-stiff neck
-photophobia
-confusion
-disorientation
What is often seen on PE for bacterial meningitis?
-fever, buth hypothermia in younger kids
-increased ICP, bradycardia and HTN
-Kernig and Brudzinki signs
In reactive adenopathy, how do nodes feel?
-rubbery, mobile with a diamter less than 2cm
What is lymphadenopathy?
infection of the nodes itself
What are the MCCs of lymphadenopathy?
GABHS or S. aureus
What is found on PE for lymphademopathy?
-poorly mobile, soft tissue edema, erythema greater than 2cm
-tonsillar and anterior cervical nodes are mainly involved
Tell me about the findings of atypical mycobaceria lymphadenopathy in those less than 4.
-submandibular, perauricular, anterior cervical, inguinal, or epitrochlear nodes
-bilateral adenitis isn't present
-no fever or other sx
-mildly tender, little warmth or inflammation
-after several weeks, nodes become fixed and discolorded
Moratility in bacterial meningitis is highest with what bug in children?
S. pneumoniae
What types of bugs infect infants and older infants and cause meningitis?
-enteric pathogens in infants and encapsulated bacteria in older infants and children
What is seen in the hx of of an infant and young child with bacterial meningitis?
-irritable
-anorexia
-vomiting
-inconsolable crying
-lethargy
-seizures
-focal neurological signs
What is seen in the hx of an older child with bacterial meningitis?
-HA
-back pain
-stiff neck
-photophobia
-confusion
-disorientation
What is often seen on PE for bacterial meningitis?
-fever, buth hypothermia in younger kids
-increased ICP, bradycardia and HTN
-Kernig and Brudzinki signs
What is seen in the CSF of bacterial meningitis pts?
-cloudy
-PMNs
-protein elevation
-low glucose
-gram stain positive
What virus is the leading cause of severe encephalitis?
HSV
What are arboviruses that can cause encephalitis?
-arboviruses are RNA viruses that cause either aseptic meningitis or encephalitis usually from a tick or mosquito virus
What are different types of encephalitis caused by tick or mosquito bites?
-St. Louis encephalitis
-Western Equine
-Eastern Equine
-California encephalitis
-West Nile Virus
Neurological sequelae are most often found in what types of encephalitis?
eastern equine and St. Louis
Moratlity is high in what type of encephalitis?
eastern equine
What is found in the hx for encephalitis?

ps-they are nonspecific for encephalitis alone
-fever
-irritablity
-lethargy
-anorexia
-rhinorrhea
-pharyngitis
-cough
-diarrhea
-vomiting
-rash
What can be seen on PE for encephalitis?
-LOC
-CN abnormalities
-hemiparesis
-ataxia
What is seen in the CSF for encephalitis?
-lymphocytic pleocytosis
-elevated protein
-normal or mild decrease in glucose
Pyogenic or septic arthritis is the result of what?
bacterial infection of the joint space
What is reactive arthritis?
an inflammatory response in the joint space that occrus at the result of infectin elsewhere
Infectious arthritis is most common in those under what age?
3
WHat joints are most often affected in infectious arthritis?
knees, hips, ankles
What bugs tend to cause infectious arthritis?
-GABHS
-N. miningitidis
-gonorrhea
-salmonella
Pyogenic arthris typically presents with what?
acute pain in the affected joint
What are some PE findings in infectious arthritis in children?
-affected joint is swollen, warm and tender
-ROM is decreased
Why is hip difficult to find PE findings on?
-no red, warm, or swelling, and pain may refer to the knee

-child may hold hip flexed, externally rotated, and abducted
What labs are elevated in infectious arthritis?
ESR, WBC, and CRP
What are some other tests you can do in infectious arthritis?
-X-rays
-US for fluid
-MRI
Osteomyelitis is usually caused by what?
bateria
Osteomyelitis:

-males_______ females

-lower extremities_____upper
males greater than females

lower extremities greater than upper
What is the most common bug to cause osteomyelitis?
S. aureus
What is often seen on hx for osteomyelitis?
fever and malaise and refusal to bear weight on affected limb
In osteomyelitis, palpation of the affected bone reveals what?
tenderness
MRubeola (measles) most often occur when?
winter or spring
What is seen in the hx of someone with rubeola?
-high fever
-dry cough
-coryza
-conjunctivitis with clear discharge
What is pathognomonic for rubeola?
Koplik spots
In rubeola when does the rash appear?
3-4 days after onset of prodromal sx
Tell me about the evolution of the rash in rubeola?
begins at hairline and psread to involve trunk, arms, legs and then hands and feet
Rubella/German Measles season is when?
winter or early spring
What are the most common complications of Rubella?
arthritis and arthralgia that mostly affects fingers, wrists, and knees
What is seen in the hx or Rubella?
-low grade fever
-malaise
-lymphadenopathy
-URI
What lymph nodes tend to be enlarged in Rubella?
post auricular, suboccipital, posterior cervical
In Rubella, the rash often begins how many days after symptoms start?

Their evolution?
1-5 days

-begin on face and progress caudally and DO NO coalesce
What are the 2 other names for Roseola?
-Exanthem Subitum
-6th disease
Roseola is uaully from what and remains latent where?
-usually from infected saliva from parents/siblings and remains latent in mononuclear cells
What is seen in the hx for Roseola?
-few prodromal sx and an abrupt onset of fever that lasts 3-7 days

-some GI sx
What is seen on PE for Roseola?
-high fever, but mainly normal otherwise
-cervical lymphadenopathy or AOM
-erythematous maculopapular rash that resolves spontaneously
Parvovirus B 19 is transmitted how?
contact with respiratory secretions
When are you most contagious in B19 infection?
in prodromal period
Why does B19 cause anemia in children?
because the virus affects RBC precursors
What is seen on the hx for B19 infection?
low grade fever, URI sx, and malaise
What is seen on PE for B19 infection?
red flat rash on the cheeks and lacy, reticular, often pruritic rash on the trunk and extremities
-may get worse with warm temps
B19 may cause an _____ crisis
aplastic
Varicella produces what kind of rash?
generalized pruitic vesicular rash
When is varicella contagious?
from 1-2 days before onset of the rash until lesions crust
What is seen on hx for varicellia?
fever and malaise
Tell me about the rash in Varicella?
begins on neck, face or uppper trunk and spreads outwards in 3-5 days
In Varicella, what does a Tzanck smear reveal?
multinulceated giant cells
The rash of scarlet fever results from what?
vascular effects of strep pyrogenic exotoxins A, B and C from GABHS
GABHS can cause what things?
-impetigo
-cellulitis
-erysipelas
-necrotizing fasciitis
What are the prodromal symptoms of scarlet fever?
-fever
-pharyngitis
-chills
-ab pain
-rash 1-2 days after sx
Tell me about the rash in scarlet fever
-erythematous and blanching, with fine sandpaper like papules on palpation
The rash in scarlet fever is prominent where?
warm, moist areash and spares the mouth (Pastia lines)
In scarlet fever fine desquamation starts on the face and spreads where?
to the trunk and extremities
Staph Aureus is an exfoliative toxin that causes what?
-bullous impentigo
-staph scalded skin syndrome
-scarlatiniform eruption
-cellulitis
-TSS
Rocky Mountain Spotted fever is caused by what?
-tick bite
What are the prodromal symptoms of RMSF?
-HA
-fever
-malaise
-N/V
-ab pain
-diarrhea
Tell me about the rash in RMSF.
-appears after 3rd day, begins peripherally on the wrists, ankles, and lower legs and speads centrally
What lab can be run for RMSF?
Rickettsial Group Specific Test
What drug is used to tx RMSF?
tetracyclines
N. Meningitidis can cause what things?
-chronic bacteremia
-acute bacteremia with sepsis
-meningitis
What is the prodrome of n. meningitidis?
fever, phryngitis, and HA
What may be seen on PE for N. Meningitidis?
-fever
-hypotension
-poor perfusion
-cyanosis
-petechiae or purpuric skin lesions
What is DOC for N. Meningitidis?
PCN
90% of Peds get HIV how?
perinatal transmission
In the first 2-3 months in peds HIV they can develop what?
PCP
Tell me about testing infants exposed to HIV.
-PCR for HIV viral DNA 48 hrs after birth and repeated at 1 and 3 months of age
If a child is over 18, how do you test for HIV?
-serologic tests are negative 3-4 weeks after acute infection

-do ELISA and confirm by Western blot
In adolescents with HIV viral RNA in plasma is negative for how long before test will be positive?
1-3 weeks
WHat increases and decreases in children with HIV?
-increased CD8

-decreased CD4 and lymphocytes
Tell me about treating HIV in children.
-two NRTIs plus either a protease inhibitor or an NNRTI
-babies born to HIV+ mothers should take AZT (can cause anemia)
-breastfeeding is not recommended
TB is transmitted how?
when an infected person releases infected droplets of mucus into the air
TB likes to infect what areas of the body?
-eyes
-ears
-skin and bone
-GU tract
What is seen on PE in TB?
-wt loss, fever, lymphadenitis, hepatosplenomegaly, abnormal neuro exam
What is the most common extra pumonary manifestation of TB?
TB lymphadenitis (scrofula)
What are some risk factors for the development of Lyme Disease?
-live in overgrowth with tick-infested brush as well as occupational or recretional exposure
What is the hallmark sign of Lyme Disease?
erythema chonicum migrans
What is seen on hx and PE for lyme disease?
-fever
-HA
-malaise
-lymphadenopathy
What happens in the 2nd stage of Lyme Disease?
Dissemination, arthralgia and cardiac abnormalities
What happens in the 3rd stage of Lyme Disease?
pauciarticular arthritis