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55 Cards in this Set
- Front
- Back
what is the tx for the symtoms of change in mental status, hypoventilation?
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airway support
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__ and __ are used to treat the symptoms of hypotension
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IV fluids and vasopressors
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for the symptoms of HTN and agitiation r/t overdose, what is the tx?
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sedatives and benzos
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what the is tx for HTN cause by overdose?
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CCBs, or beta blockers, with vasodilator
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what are the 2 ways to decontaminate the gut?
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NG tube; charcoal
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what is the way to decontaminate the blood?
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hemodialysis
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what is the most common overdose in the ED?>
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tylenol
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what organ is impacted the greatest with Tylenol OD?
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liver
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what are the lcinical symptoms of tylenol OD in the 1st few hours?
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NV, anorexia
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what symptom of tylenol OD occurs 8-24 hours after ingestion?
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asymptomatic period
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what occurs 24-48 hours after tylenol OD?
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subclinical hepatotox, increased LFTs, RUQ pain, NV
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what occurs after 48 hours since tylenol OD?
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fulminant hepatic failure, jaundice, renal failure, cerebral edema, hypotension
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what labs are required following a tylenol OD?
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cbc, chem 20, PT/PTT, tylenol level, tox screen
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how are anticholingeric Ods dx?>
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clinically, no tox lab for this
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what are the symptoms of anticholinergic OD?
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dry mouth, flushed dry skin, mydriatic & unreactive pupils, blurred vision, constipation, urinary retention, tachycardia, confusion, disorientation, hallucinations, sz, coma
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what is the mnemonic for anticholinergic Ods?
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Dry as a bone; mad as a hatter; red as a beat; hot as hades; blind as a bat
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what is the ED management for anticholinergic OD?
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IV access, start charcoal if w/in 4 hours; glucose levels; intubate if in coma; sz give lorazepam 0.05-0.1mg/kg IV or diapzepam 0.1-0.3 mg/kg IV; wide complex tachycardia give bicarb 1mEq/kg IV
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what is the ED management for tylenol OD?
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if < 4 hours after ingestion give charcoal; mucomyst 140mg/kg PO followed by 70mg/kg q 4 hours x17 doses of mucomyst; IV antiemetics
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the goal of ed management of tylenol OD is to have a level ____
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< 10 ug/mL and normal ASTs
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what are the side effects of SSRIs?
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drowsiness, dry mouth, blurred vision, constpation, urinary retention and less cardiac side effects
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what are the common side effects of SSRIs?
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NV; dyspepsia, sex dysfunc; HA; insomnia; dizzy; anxiety; agitiation; tremor; sweating
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what are the OD symptoms from SSRIs?
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extreme of side effects: tachy with drowsiness; extreme seizures, prolonged QT; tachyarrythmias
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what are the symptoms of seratonin syndorm?
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mental status change; restlesness; myoclonus; hyper reflexia; sweating; shivering; tremor; diarrhea; incoordination; fever
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what are the complications of seratonin syndrome?
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sz, severe hypethermia, rhabdomyalysis, DIC, resp arrest, death
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when can charcoal be given for SSRI overdose?
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within 1 hour of OD
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what is the length of time to observe a person with SSRI overdose?
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4-6 hours
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what is given for sedation for SSRI OD?
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Diazepam 0.1-0.3 mg/kg
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how many tabs of antipsychotics does it take to OD a child?
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1
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what are the neuro symptoms of antipsychotic OD?
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sedation; CNS depression; lowers sz threshold, dystonia; actue akasthesia
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what are the cardiac symptoms of antipsyhcotic OD?
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hypotension; tachycardia; prolonged QT-torsades; peripheral vasodilation
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when can charcoal be given for antipsychotic OD?
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w/in 1 hour of ingestion
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what condition can you not give charcoal following antipsychotic OD?
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> 1hour or encephalopathic
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what are the tx for antipsychotic OD?
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IV line, ecg, tox screen, ASA, tylenol level, CBC, chem 20, CPK, CXR if CNS depression
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how do you tx the hypotension cause by antipsychotic OD?
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IV NS, if persists give Epi or Norepi gtt
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what is the tx for prolonged QT caused by antipsychotic OD?
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mag sulfate
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how do you tx the sz caused by antipsychotic OD?
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benzos
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what are the worst of the worst drugs to OD on?
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tricyclics
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what are the common tricyclics?
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tofranil, elavil, sinequan (doxepin)
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what is the pathophysiology of tricyclic OD?
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induced direct myocaridal depression, inhibition of norepi uptake and anticholingeric activity
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what are the clinical anticholinergic effects of tricyclic OD?
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tachycardia and confusion
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what are the peripheral alpha blockage clinical symptoms from tricyclic OD?
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hypotention
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what causes the widened QT from tricyclic OD?
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sodium channel blockage
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the gaba inhibition caused by tricyclic causes __
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seizures
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ToF: acidosis is a clinical presentation of tricyclic OD
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TRUE
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what are the mental status changes that occur from tricyclic OD?
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combativeness, delirium, hallucinations, lethargy, coma
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how do the cardiac symptoms of tricyclic OD progress?
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start with tachycardia and HTN, then get hypotensive; tachyarrythmias are the common cause of death (ventricular arrythmias)
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when do you suspect an OD of tricyclics?
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pt presenting with acute change of mental status, seizures, abnormal vital signs or an arrhythmia
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is the QRS is > ____ ms &/or has a __ ___ __ most likely tricyclic has been ingested
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>100; right axis deviation
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if the QRS wave is > ___ms with a __ wave or more than __ mm tall, think tricyclic
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40ms; R; 3
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how many hours after ingestion of tricyclics can charcoal be given?
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4
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what is the management for tricyclic OD when QRS > 100ms?
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give 1-2mEW/kg of sodium bicarb over 2 mins and repeate q 5 mins til ORS narrows < 10ms
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ToF: you must tx the hypternsion that is caused by tricyclic OD
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fALSE!! They will always become hypotensive
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how do you tx the hypotension of tricyclic OD?
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20mL/kg boluses; Norepi gtt 0.1-0.2 ug/kg/min titrate to b/p;
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for life threatening ventricular arrhythmias from tricyclic OD give __-
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lidocaine
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ToF: you must tx SVTs caused by tricyclic OD
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false; you may need to pace patient.
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