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55 Cards in this Set

  • Front
  • Back
what is the tx for the symtoms of change in mental status, hypoventilation?
airway support
__ and __ are used to treat the symptoms of hypotension
IV fluids and vasopressors
for the symptoms of HTN and agitiation r/t overdose, what is the tx?
sedatives and benzos
what the is tx for HTN cause by overdose?
CCBs, or beta blockers, with vasodilator
what are the 2 ways to decontaminate the gut?
NG tube; charcoal
what is the way to decontaminate the blood?
hemodialysis
what is the most common overdose in the ED?>
tylenol
what organ is impacted the greatest with Tylenol OD?
liver
what are the lcinical symptoms of tylenol OD in the 1st few hours?
NV, anorexia
what symptom of tylenol OD occurs 8-24 hours after ingestion?
asymptomatic period
what occurs 24-48 hours after tylenol OD?
subclinical hepatotox, increased LFTs, RUQ pain, NV
what occurs after 48 hours since tylenol OD?
fulminant hepatic failure, jaundice, renal failure, cerebral edema, hypotension
what labs are required following a tylenol OD?
cbc, chem 20, PT/PTT, tylenol level, tox screen
how are anticholingeric Ods dx?>
clinically, no tox lab for this
what are the symptoms of anticholinergic OD?
dry mouth, flushed dry skin, mydriatic & unreactive pupils, blurred vision, constipation, urinary retention, tachycardia, confusion, disorientation, hallucinations, sz, coma
what is the mnemonic for anticholinergic Ods?
Dry as a bone; mad as a hatter; red as a beat; hot as hades; blind as a bat
what is the ED management for anticholinergic OD?
IV access, start charcoal if w/in 4 hours; glucose levels; intubate if in coma; sz give lorazepam 0.05-0.1mg/kg IV or diapzepam 0.1-0.3 mg/kg IV; wide complex tachycardia give bicarb 1mEq/kg IV
what is the ED management for tylenol OD?
if < 4 hours after ingestion give charcoal; mucomyst 140mg/kg PO followed by 70mg/kg q 4 hours x17 doses of mucomyst; IV antiemetics
the goal of ed management of tylenol OD is to have a level ____
< 10 ug/mL and normal ASTs
what are the side effects of SSRIs?
drowsiness, dry mouth, blurred vision, constpation, urinary retention and less cardiac side effects
what are the common side effects of SSRIs?
NV; dyspepsia, sex dysfunc; HA; insomnia; dizzy; anxiety; agitiation; tremor; sweating
what are the OD symptoms from SSRIs?
extreme of side effects: tachy with drowsiness; extreme seizures, prolonged QT; tachyarrythmias
what are the symptoms of seratonin syndorm?
mental status change; restlesness; myoclonus; hyper reflexia; sweating; shivering; tremor; diarrhea; incoordination; fever
what are the complications of seratonin syndrome?
sz, severe hypethermia, rhabdomyalysis, DIC, resp arrest, death
when can charcoal be given for SSRI overdose?
within 1 hour of OD
what is the length of time to observe a person with SSRI overdose?
4-6 hours
what is given for sedation for SSRI OD?
Diazepam 0.1-0.3 mg/kg
how many tabs of antipsychotics does it take to OD a child?
1
what are the neuro symptoms of antipsychotic OD?
sedation; CNS depression; lowers sz threshold, dystonia; actue akasthesia
what are the cardiac symptoms of antipsyhcotic OD?
hypotension; tachycardia; prolonged QT-torsades; peripheral vasodilation
when can charcoal be given for antipsychotic OD?
w/in 1 hour of ingestion
what condition can you not give charcoal following antipsychotic OD?
> 1hour or encephalopathic
what are the tx for antipsychotic OD?
IV line, ecg, tox screen, ASA, tylenol level, CBC, chem 20, CPK, CXR if CNS depression
how do you tx the hypotension cause by antipsychotic OD?
IV NS, if persists give Epi or Norepi gtt
what is the tx for prolonged QT caused by antipsychotic OD?
mag sulfate
how do you tx the sz caused by antipsychotic OD?
benzos
what are the worst of the worst drugs to OD on?
tricyclics
what are the common tricyclics?
tofranil, elavil, sinequan (doxepin)
what is the pathophysiology of tricyclic OD?
induced direct myocaridal depression, inhibition of norepi uptake and anticholingeric activity
what are the clinical anticholinergic effects of tricyclic OD?
tachycardia and confusion
what are the peripheral alpha blockage clinical symptoms from tricyclic OD?
hypotention
what causes the widened QT from tricyclic OD?
sodium channel blockage
the gaba inhibition caused by tricyclic causes __
seizures
ToF: acidosis is a clinical presentation of tricyclic OD
TRUE
what are the mental status changes that occur from tricyclic OD?
combativeness, delirium, hallucinations, lethargy, coma
how do the cardiac symptoms of tricyclic OD progress?
start with tachycardia and HTN, then get hypotensive; tachyarrythmias are the common cause of death (ventricular arrythmias)
when do you suspect an OD of tricyclics?
pt presenting with acute change of mental status, seizures, abnormal vital signs or an arrhythmia
is the QRS is > ____ ms &/or has a __ ___ __ most likely tricyclic has been ingested
>100; right axis deviation
if the QRS wave is > ___ms with a __ wave or more than __ mm tall, think tricyclic
40ms; R; 3
how many hours after ingestion of tricyclics can charcoal be given?
4
what is the management for tricyclic OD when QRS > 100ms?
give 1-2mEW/kg of sodium bicarb over 2 mins and repeate q 5 mins til ORS narrows < 10ms
ToF: you must tx the hypternsion that is caused by tricyclic OD
fALSE!! They will always become hypotensive
how do you tx the hypotension of tricyclic OD?
20mL/kg boluses; Norepi gtt 0.1-0.2 ug/kg/min titrate to b/p;
for life threatening ventricular arrhythmias from tricyclic OD give __-
lidocaine
ToF: you must tx SVTs caused by tricyclic OD
false; you may need to pace patient.