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19 Cards in this Set

  • Front
  • Back
Common symptoms
poor oral intake, fever, vomiting, migratory abdominal pain
Pediatric appendicitis score
Migratory pain, nausea and vomiting, anorexia, fever, cough/percussion/hopping (2), RLQ tenderness (2), WBC > 10K, PMNs >7500
Meta-analyses comparing lap vs. open appendectomy
-Decreased length of stay 2.4 hours
-Decreased wound infection 1-2 vs 5-6%
-Operative time the same or shorter.
-Superior quality of life at 2 weeks.
-Reduces rate of postoperative small bowel obstructions.
-Also allows thorough inspection of the abdomen to address other etiologies of abdominal pain.
Treatment of perforated appendicitis (operative vs. nonoperative)
Early appendectomy was associated with significantly shorter time to return to normal activities (14 vs 19 d), reduced adverse events (abscess, small bowel obstruction, unplanned readmission, 30 vs. 55%).
Duration of antibiotics in perforated appendicitis
Limited data. Many use resolution of pain, return of bowel function, and normalization of WBC and fever.
Data for duration of therapy in perforated appendicitis
IV antibiotics for 3 days did not have an increased number of infectious complications compared to those treated for longer periods. However APSA recommends minimum 5 days.
Randomized data for IV vs PO abx for perforated appendicitis
IV for 5 days vs. IV until tolerating PO then Augmentin. No difference in postoperative abscess rate. Discharge before day 5 was possible in 42% in IV/PO group.
Rationale for nonoperative therapy in perforated appendicitis with abscess formation
Meta-analysis of 56,000 patients, 4% with abscess or phlegmon. 36% who underwent immediate surgery had morbidity, inc postop infection, intestinal fistula, SBO, or recurrence. OR 3.4 compared to the nonoperative group.
Number of cases per year
70,000
Risk lifetime
8.7% for boys, 6.7% for girls
Peak incidence
12 to 18 years
Rate of postoperative abscess
1% for acute, 20% for perforated
Causes of obstruction causing appendicitis
Lymphoid hyperplasia, inspissated fecal matter, foreign body, parasites
Next stage in evolution of appendicitis
Lymphoid and venous congestion, causing edema, and eventually blockage of arterial inflow. Eventually leads to necrosis and perforation.
Odd causes of appendicitis
Yersinia, Salmonella, Shigella, mumps, coxsackievirus B and adenovirus. CF kids can get painful distention of the appendix from abnormal mucus production.
Sensitivity/specificity of ultrasound
Sens 78% to 94%, specificity 89 to 98%.
CT sensitivity/specificity
95% or greater
DDx of appendicitis
tubo-ovarian process, Crohn disease, Meckel diverticulum, UTI, pneumonia, gastroenteritis,
Risk of recurrent appendicitis for nonoperatively managed appendicitis?
8 to 14% but is short term follow up only. Does not take into account the life expectancy of pediatric patients.