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19 Cards in this Set

  • Front
  • Back

Failure to thrive

physical sign not a final diagnosis




suspected if a child's growth below 3rd or 5th percentile in child less than 6 months old who does not gain weight for 2-3 months or in a child whose growth cross more than 2 major growth percentiles in a short time frame




usually in children less than 5 who are significantly smaller than their peers

Major causes of inadequate weight gain

p.20 Case files




inadequate caloric intake


altered growth potential


caloric wasting


increased caloric requirements

Healthy infants require how many calories per day in first year?


For FTT?

120kcal/kg/day

and 100 kcal/kg/day thereafter




FTT require 50-100 percent more

congenital CMV

developmental delay, IUGR (microcephaly), cataracts, seizures, HSM, prolonged neonatal jaundice, purura




periventricular calcified brain densities




toxo - scattered throughout cortex

premies

use appropriate growth chart

picky eaters

18-30 months


growth rates can plateau


counsel parents to avoid force feeding and snacks

renal tubular acidosis

low bicarb, low K, elevated chloride levels




type 2 - proximal - impaired tubular absorption of bicarb




distal - type 1 - impaired hydrogen ion secretion

substance abuse in adolescents

new-onset truant behavior, depression or euphoria, declining grades

Clinical features of substance abuse:


alcohol, marijuana, cocaine, meth and ecstasy, heroin, PCP, and barbituates

case files p.30

trisomy 18

clenched hands with overlapping digits, small palebral fissures, prominent occiput, short sternum, and cardiac defects (VSD, ASD, PDA, and coarct)

AV canal defect

slight cyanosis since mixing of deoxygenated with oxygenated




complete - ASD, VSD, common AV valve




partial - defects of the atrial septum, and separate and mitral and tricuspid orifices

trisomy 13

cutis aplasia, polydactyly, holoprosencephaly, cleft lip or palate, postaxial polydactyly, flexed and overlapping fingers, colobroma, cardiac defects (VSD, ASD, PDA, dextrocardia)

HIV infection

vertical transmission




dx in younger patients made by PCR


>18 months ELISA




PCP prophylaxis - TMP-SMX




exposed - receive 6 weeks of antiretroviral zidovudine




immunizations kept current

3 major categories of anti-retrovirals

NRTIs (didanosine, stavudine, zidovudine)


nonNRTIs (efavirenz, nevirapine)


protease inhibitors (indinavir, nelfinavir)




current pediatric (2 NRTIs, and 1 protease inhibitor)

immunosuppression

difficult to eradicate infections


FTT

Diabetes Mellitus -> immunosuppression

hyperglycemia -> neutrophil dysfunction -> ineffective neutrophil chemotaxis

leukocyte adhesion deficiency

inheritable disorder of leukocyte chemotaxis and adherence


recurrent sinopulmonary, oropharyngeal, and cutaneous infections with delayed wound healing


neutrophilia with WBCs greater 50,000




Stap, Enterobacteriaceae, and Candida

SCID

AR and X linked of both humoral and cellular immunity




IgG and T cells are diminished


thymic dysgenesis




recurrent cutaneous, GI, or pulmonary infections with CMV and Pneumocystis




death occurs in first 12-24 months of life if bone marrow transplantation not performed

DiGeorge Syndrome

22q11 microdeletion


decreased T cell production and recurring infection


VSD, tetralogy of fallot, thymic or parathyroid dysgenesis




hypocalcemia and seizures




developmental and speech delay are common in patients